Effect of methotrexate on collagen-induced arthritis assessed by micro-computed tomography and histopathological examination in female rats

Biomolecules and Therapeutics

Volumn 23, Issue 2, 2015, Pages 195-200

  Kim, Young Hee ^a   Kang, Jin Seok ^a  

^a Namseoul University   (South Korea)

Author keywords

Arthritis; Collagen; Histopathology; Micro computed tomography

Indexed keywords

COLLAGEN TYPE 2; METHOTREXATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MASS; BONE STRUCTURE; CARTILAGE DEGENERATION; CELL INFILTRATION; COLLAGEN-INDUCED ARTHRITIS; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HISTOPATHOLOGY; INFLAMMATORY CELL; JOINT DESTRUCTION; KNEE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; RAT; TRABECULAR BONE;

RATTUS;

EID: 84923531872     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2014.125     Document Type: Article

References (24)

1. Afara, I. O., Prasadam, I., Crawford, R., Xiao, Y. and Oloyede, A. (2013) Near infrared (NIR) absorption spectra correlates with subchondral bone micro-CT parameters in osteoarthritic rat models. Bone53, 350-357.
2. Bevaart, L., Vervoordeldonk, M. J. and Tak, P. P. (2010) Evaluation of therapeutic targets in animal models of arthritis: how does it relate to rheumatoid arthritis? Arthritis Rheum. 62, 2192-2205.
3. Brand, D. D., Latham, K. A. and Rosloniec, E. F. (2007) Collagen-induced arthritis. Nat. Protoc. 2, 1269-1275.
4. Carvalheiro, H., da Silva, J. A. and Souto-Carneiro, M. M. (2013) Potential roles for CD8(+) T cells in rheumatoid arthritis. Autoimmun. Rev.12, 401-409.
5. Conway, J. R., Carragher, N. O. and Timpson, P. (2014) Developments in preclinical cancer imaging: innovating the discovery of therapeutics. Nat. Rev. Cancer14, 314-328.
6. Gerwin, N., Bendele, A. M., Glasson, S. and Carlson, C. S. (2010) The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rat. Osteoarthritis Cartilage18Suppl 3, S24-34.
7. Ishikawa, T., Nishigaki, F., Miyata, S., Hirayama, Y., Minoura, K., Imanishi, J., Neya, M., Mizutani, T., Imamura, Y., Naritomi, Y., Murai, H., Ohkubo, Y., Kagayama, A. and Mutoh, S. (2005) Prevention of progressive joint destruction in collagen-induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031. Br. J. Pharmacol.144, 133-143.
8. Koba, W., Jelicks, L. A. and Fine, E. J. (2013) MicroPET/SPECT/CT imaging of small animal models of disease. Am. J. Pathol.182, 319-324.
9. Maruotti, N., Cantatore, F. P., Crivellato, E., Vacca, A. and Ribatti, D. (2007) Macrophages in rheumatoid arthritis. Histol. Histopathol.22, 581-586.
10. Mello, S. B., Barros, D. M., Silva, A. S., Laurindo, I. M. and Novaes, G. S. (2000) Methotrexate as a preferential cyclooxygenase 2 inhibitor in whole blood of patients with rheumatoid arthritis. Rheumatology (Oxford)39, 533-536.
11. Myers, L. K., Rosloniec, E. F., Cremer, M. A. and Kang, A. H. (1997) Collagen-induced arthritis, an animal model of autoimmunity. Life Sci. 61, 1861-1878.
12. Nagase, H. and Woessner, J. F., Jr. (1999) Matrix metalloproteinases. J. Biol. Chem.274, 21491-21494.
13. Otero, M. and Goldring, M. B. (2007) Cells of the synovium in rheumatoid arthritis. Chondrocytes. Arthritis Res. Ther.9, 220.
14. Perkins, D. J., St Clair, E. W., Misukonis, M. A. and Weinberg, J. B. (1998) Reduction of NOS2 overexpression in rheumatoid arthritis patients treated with anti-tumor necrosis factor alpha monoclonal antibody (cA2). Arthritis Rheum. 41, 2205-2210.
15. Peterson, J. D., Labranche, T. P., Vasquez, K. O., Kossodo, S., Melton, M., Rader, R., Listello, J. T., Abrams, M. A. and Misko, T. P. (2010) Optical tomographic imaging discriminates between disease-modifying anti-rheumatic drug (DMARD) and non-DMARD efficacy in collagen antibody-induced arthritis. Arthritis Res. Ther.12, R105.
16. Ritsma, L., Vrisekoop, N. and van Rheenen, J. (2013) In vivo imaging and histochemistry are combined in the cryosection labelling and intravital microscopy technique. Nat. Commun. 4, 2366.
17. Ryu, J. H., Lee, A., Chu, J. U., Koo, H., Ko, C. Y., Kim, H. S., Yoon, S. Y., Kim, B. S., Choi, K., Kwon, I. C., Kim, K. and Youn, I. (2011) Early diagnosis of arthritis in mice with collagen-induced arthritis, using a fluorogenic matrix metalloproteinase 3-specific polymeric probe. Arthritis Rheum. 63, 3824-3832.
18. Schambach, S. J., Bag, S., Schilling, L., Groden, C. and Brockmann, M. A. (2010) Application of micro-CT in small animal imaging. Methods50, 2-13.
19. Scott, D. L. (2012) Biologics-based therapy for the treatment of rheumatoid arthritis. Clin. Pharmacol. Ther.91, 30-43.
20. Scott, D. L., Wolfe, F. and Huizinga, T. W. (2010) Rheumatoid arthritis. Lancet376, 1094-1108.
21. Segawa, Y., Yamaura, M., Aota, S., Omata, T., Tuzuike, N., Itokazu, Y., Oka, H., Tamaki, H. and Nakamura, T. (1997) Methotrexate maintains bone mass by preventing both a decrease in bone formation and an increase in bone resorption in adjuvant-induced arthritic rats. Bone20, 457-464.
22. Takaishi, H., Kimura, T., Dalal, S., Okada, Y. and D'Armiento, J. (2008) Joint diseases and matrix metalloproteinases: a role for MMP-13. Curr. Pharm. Biotechnol.9, 47-54.
23. Weinblatt, M. E., Kaplan, H., Germain, B. F., Merriman, R. C., Solomon, S. D., Wall, B., Anderson, L., Block, S., Small, R., Wolfe, F. and et al. (1991) Methotrexate in rheumatoid arthritis: effects on disease activity in a multicenter prospective study. J. Rheumatol. 18, 334-338.
24. Weinblatt, M. E., Weissman, B. N., Holdsworth, D. E., Fraser, P. A., Maier, A. L., Falchuk, K. R. and Coblyn, J. S. (1992) Long-term prospective study of methotrexate in the treatment of rheumatoid arthritis. 84-month update. Arthritis Rheum. 35, 129-137.