-
1
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002;417(6892):949-54
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
2
-
-
77956030786
-
'Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty KT, Puzanov I, Kim KB, et al. 'Inhibition of mutated, activated BRAF in metastatic melanoma.' N Engl J Med 2010; 363(9):809-19
-
(2010)
' N Engl J Med
, vol.363
, Issue.9
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
-
3
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001; 344(14):1031-7
-
(2001)
N Engl J Med
, vol.344
, Issue.14
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
4
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Fong PC, Boss DS, Yap TA, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009;361(2):123-34
-
(2009)
N Engl J Med
, vol.361
, Issue.2
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
-
5
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
-
Rosell R, Carcereny E, Gervais R, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012;13(3): 239-46
-
(2012)
Lancet Oncol
, vol.13
, Issue.3
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
-
6
-
-
84904624695
-
Clinical activity of the mutant-selective EGFR inhibitor AZD9291 in patients (pts) with EGFR inhibitor-resistant non-small cell lung cancer (NSCLC)
-
Janne PA, Ramalingam SS, Chih-Hsin Yang J, et al. Clinical activity of the mutant-selective EGFR inhibitor AZD9291 in patients (pts) with EGFR inhibitor-resistant non-small cell lung cancer (NSCLC). J Clin Oncol 2014; 32(5 Suppl):abstr 8009
-
(2014)
J Clin Oncol
, vol.32
, Issue.5
, pp. 8009
-
-
Janne, P.A.1
Ramalingam, S.S.2
Chih-Hsin Yang, J.3
-
7
-
-
84904657511
-
First-in-human evaluation of CO-1686, an irreversible, highly selective tyrosine kinase inhibitor of mutations of EGFR (activating and T790M)
-
Sequist LV, Soria JC, Gadgeel SM, et al. First-in-human evaluation of CO-1686, an irreversible, highly selective tyrosine kinase inhibitor of mutations of EGFR (activating and T790M). J Clin Oncol 2014; 32(5 Suppl):abstr 8010
-
(2014)
J Clin Oncol
, vol.32
, Issue.5
, pp. 8010
-
-
Sequist, L.V.1
Soria, J.C.2
Gadgeel, S.M.3
-
8
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M, Rowan AJ, Horswell S, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012;366: 883-92
-
(2012)
N Engl J Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
-
9
-
-
84864450130
-
Tumour molecular profiling for deciding therapy - The French initiative
-
Nowak F, Soria JC, Calvo F. Tumour molecular profiling for deciding therapy-the French initiative. Nat Rev Clin Oncol 2012;9(8):479-86
-
(2012)
Nat Rev Clin Oncol
, vol.9
, Issue.8
, pp. 479-486
-
-
Nowak, F.1
Soria, J.C.2
Calvo, F.3
-
10
-
-
84923374984
-
Five-fold increase in recruitment of cancer patients to National Institute for Health Research cancer research network portfolio studies between 2001 and 2011
-
Cooper M, Poole K, Cameron DA, et al. Five-fold increase in recruitment of cancer patients to National Institute for Health Research cancer research network portfolio studies between 2001 and 2011. J Clin Oncol 2012;30(15 Suppl):abstr 6091
-
(2012)
J Clin Oncol
, vol.30
, Issue.15
, pp. 6091
-
-
Cooper, M.1
Poole, K.2
Cameron, D.A.3
|