-
1
-
-
34547228831
-
Atypical mitogen-activated protein kinase: Structure, regulation and functions
-
PMID: 17161475
-
Coulombe P, Meloche S (2007) Atypical mitogen-activated protein kinase: Structure, regulation and functions. Biochim Biophys Acta 1773:1376-1387. PMID: 17161475
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1376-1387
-
-
Coulombe, P.1
Meloche, S.2
-
2
-
-
80755148776
-
MEK5/ERK5 pathway: The first fifteen years
-
PMID: 22020294
-
Drew BA, Burow ME, Beckman BS (2012) MEK5/ERK5 pathway: the first fifteen years. Biochim Biophys Acta 1825:37-48. doi: 10.1016/j.bbcan. 2011.10.002 PMID: 22020294
-
(2012)
Biochim Biophys Acta
, vol.1825
, pp. 37-48
-
-
Drew, B.A.1
Burow, M.E.2
Beckman, B.S.3
-
3
-
-
84865309012
-
ERK5: Structure, regulation and function
-
PMID: 22800864
-
Nithianandarajah-Jones GN, Wilm B, Goldring CE, Muller J, Cross MJ (2012) ERK5: structure, regulation and function. Cell Signal 24:2187-2196. doi: 10.1016/j.cellsig.2012.07.007 PMID: 22800864
-
(2012)
Cell Signal
, vol.24
, pp. 2187-2196
-
-
Nithianandarajah-Jones, G.N.1
Wilm, B.2
Goldring, C.E.3
Muller, J.4
Cross, M.J.5
-
4
-
-
37249007152
-
Activation of a C-terminal transcriptional activation domain of ERK5 by autophosphorylation
-
PMID: 17928297
-
Morimoto H, Kondoh K, Nishimoto S, Terasawa K, Nishida E (2007) Activation of a C-terminal transcriptional activation domain of ERK5 by autophosphorylation. J Biol Chem 282:35449-35456. PMID: 17928297
-
(2007)
J Biol Chem
, vol.282
, pp. 35449-35456
-
-
Morimoto, H.1
Kondoh, K.2
Nishimoto, S.3
Terasawa, K.4
Nishida, E.5
-
5
-
-
32144436881
-
Regulation of cellular functions by the ERK5 signalling pathway
-
PMID: 16376520
-
Wang X, Tournier C (2006) Regulation of cellular functions by the ERK5 signalling pathway. Cell Signal 18:753-760. PMID: 16376520
-
(2006)
Cell Signal
, vol.18
, pp. 753-760
-
-
Wang, X.1
Tournier, C.2
-
6
-
-
79151485634
-
Basic fibroblast growth factor promotes glial cell-derived neurotrophic factor gene expression mediated by activation of ERK5 in rat C6 glioma cells
-
PMID: 21130871
-
Obara Y, Nemoto W, Kohno S, Murata T, Kaneda N, et al. (2011) Basic fibroblast growth factor promotes glial cell-derived neurotrophic factor gene expression mediated by activation of ERK5 in rat C6 glioma cells. Cell Signal 23:666-672. doi: 10.1016/j.cellsig.2010.11.020 PMID: 21130871
-
(2011)
Cell Signal
, vol.23
, pp. 666-672
-
-
Obara, Y.1
Nemoto, W.2
Kohno, S.3
Murata, T.4
Kaneda, N.5
-
7
-
-
43349105734
-
(5y subunits of Gi/o suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced
-
PMID: 18407464
-
Obara Y, Okano Y, Ono S, Yamauchi A, Hoshino T, et al. (2008) (5y subunits of Gi/o suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced. Cell Signal 20:1275-1283. doi: 10.1016/j.cellsig.2008.02.016 PMID: 18407464
-
(2008)
Cell Signal
, vol.20
, pp. 1275-1283
-
-
Obara, Y.1
Okano, Y.2
Ono, S.3
Yamauchi, A.4
Hoshino, T.5
-
8
-
-
0032531881
-
Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor
-
PMID: 9790194
-
Kato Y, Tapping RI, Huang S, Watson MH, Ulevitch RJ, et al. (1998) Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor. Nature 395:713-716. PMID: 9790194
-
(1998)
Nature
, vol.395
, pp. 713-716
-
-
Kato, Y.1
Tapping, R.I.2
Huang, S.3
Watson, M.H.4
Ulevitch, R.J.5
-
9
-
-
0034804675
-
Neurotrophins use the Erk5 pathway to mediate a retrograde survival response
-
PMID: 11544482
-
Watson FL, Heerssen HM, Bhattacharyya A, Klesse L, Lin MZ, et al. (2001) Neurotrophins use the Erk5 pathway to mediate a retrograde survival response. Nat Neurosci 4:981-988. PMID: 11544482
-
(2001)
Nat Neurosci
, vol.4
, pp. 981-988
-
-
Watson, F.L.1
Heerssen, H.M.2
Bhattacharyya, A.3
Klesse, L.4
Lin, M.Z.5
-
10
-
-
33845978800
-
Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade
-
PMID: 17003042
-
Wang Y, Su B, Xia Z (2006) Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade. J Biol Chem 281:35965-35974. PMID: 17003042
-
(2006)
J Biol Chem
, vol.281
, pp. 35965-35974
-
-
Wang, Y.1
Su, B.2
Xia, Z.3
-
11
-
-
69949135616
-
ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells
-
PMID: 19581298
-
Obara Y, Yamauchi A, Takehara S, Nemoto W, Takahashi M, et al. (2009) ERK5 Activity Is Required for Nerve Growth Factor-induced Neurite Outgrowth and Stabilization of Tyrosine Hydroxylase in PC12 Cells. J Biol Chem 284:23564-23573. doi: 10.1074/jbc. M109.027821 PMID: 19581298
-
(2009)
J Biol Chem
, vol.284
, pp. 23564-23573
-
-
Obara, Y.1
Yamauchi, A.2
Takehara, S.3
Nemoto, W.4
Takahashi, M.5
-
12
-
-
0042163206
-
Activation of gp130transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes
-
PMID: 12855672
-
Nakaoka Y, Nishida K, Fujio Y, Izumi M, Terai K, et al. (2003) Activation of gp130transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes. Circ Res 93:221-229. PMID: 12855672
-
(2003)
Circ Res
, vol.93
, pp. 221-229
-
-
Nakaoka, Y.1
Nishida, K.2
Fujio, Y.3
Izumi, M.4
Terai, K.5
-
13
-
-
73549086743
-
The signaling pathway leading to extracellular signal-regulated kinase 5 (ERK5) activation via G-proteins and ERK5-dependent neurotrophic effects
-
PMID: 19858097
-
Obara Y, Nakahata N (2010) The signaling pathway leading to extracellular signal-regulated kinase 5 (ERK5) activation via G-proteins and ERK5-dependent neurotrophic effects. Mol Pharmacol 77:10-16. doi: 10.1124/mol.109.060236 PMID: 19858097
-
(2010)
Mol Pharmacol
, vol.77
, pp. 10-16
-
-
Obara, Y.1
Nakahata, N.2
-
14
-
-
12344333887
-
PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12cells
-
PMID: 15546918
-
Obara Y, Labudda K, Dillon TJ, Stork PJ (2004) PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12cells. J Cell Sci 117:6085-6094. PMID: 15546918
-
(2004)
J Cell Sci
, vol.117
, pp. 6085-6094
-
-
Obara, Y.1
Labudda, K.2
Dillon, T.J.3
Stork, P.J.4
-
15
-
-
0032499282
-
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
-
PMID: 9560161
-
York RD, Yao H, Dillon T, Ellig CL, Eckert SP, et al. (1998) Rap1 mediates sustained MAP kinase activation induced by nerve growth factor. Nature 392:622-626. PMID: 9560161
-
(1998)
Nature
, vol.392
, pp. 622-626
-
-
York, R.D.1
Yao, H.2
Dillon, T.3
Ellig, C.L.4
Eckert, S.P.5
-
16
-
-
12444285810
-
Role of the BMK1/ERK5 signaling pathway: Lessons from knockout mice
-
PMID: 15517128
-
Hayashi M, Lee JD (2004) Role of the BMK1/ERK5 signaling pathway: lessons from knockout mice. J Mol Med 82:800-808. PMID: 15517128
-
(2004)
J Mol Med
, vol.82
, pp. 800-808
-
-
Hayashi, M.1
Lee, J.D.2
-
17
-
-
70450182094
-
ERK5 and the regulation of endothelial cell function
-
PMID: 19909257
-
Roberts OL, Holmes K, Muller J, Cross DA, Cross MJ (2009) ERK5 and the regulation of endothelial cell function. BiochemSocTrans 37:1254-1259. doi: 10.1042/BST0371254 PMID: 19909257
-
(2009)
BiochemSocTrans
, vol.37
, pp. 1254-1259
-
-
Roberts, O.L.1
Holmes, K.2
Muller, J.3
Cross, D.A.4
Cross, M.J.5
-
18
-
-
84869988387
-
The maintenance of established remote contextual fear memory requires ERK5 MAP kinase and ongoing adult neurogenesis in the hippocampus
-
PMID: 23189204
-
Pan YW, Storm DR, Xia Z (2012) The Maintenance of Established Remote Contextual Fear Memory Requires ERK5 MAP Kinase and Ongoing Adult Neurogenesis in the Hippocampus. PLoS One 7:e50455. doi: 10.1371/journal.pone.0050455 PMID: 23189204
-
(2012)
PLoS One
, vol.7
, pp. e50455
-
-
Pan, Y.W.1
Storm, D.R.2
Xia, Z.3
-
19
-
-
84869755993
-
Inducible and targeted deletion of the ERK5 MAP kinase in adult neurogenic regions impairs adult neurogenesis in the olfactory bulb and several forms of olfactory behavior
-
PMID: 23185386
-
Pan YW, Kuo CT, Storm DR, Xia Z (2012) Inducible and Targeted Deletion of the ERK5 MAP Kinase in Adult Neurogenic Regions Impairs Adult Neurogenesis in the Olfactory Bulb and Several Forms of Olfactory Behavior. PLoS One 7:e49622. doi: 10.1371/journal.pone.0049622 PMID: 23185386
-
(2012)
PLoS One
, vol.7
, pp. e49622
-
-
Pan, Y.W.1
Kuo, C.T.2
Storm, D.R.3
Xia, Z.4
-
20
-
-
84860668053
-
Inhibition of adult neurogenesis by inducible and targeted deletion of ERK5 mitogen-activated protein kinase specifically in adult neurogenic regions impairs contextual fear extinction and remote fear memory
-
PMID: 22573667
-
Pan YW, Chan GC, Kuo CT, Storm DR, Xia Z (2012) Inhibition of adult neurogenesis by inducible and targeted deletion of ERK5 mitogen-activated protein kinase specifically in adult neurogenic regions impairs contextual fear extinction and remote fear memory. J Neurosci 32:6444-6455. doi: 10.1523/JNEUROSCI.6076-11.2012 PMID: 22573667
-
(2012)
J Neurosci
, vol.32
, pp. 6444-6455
-
-
Pan, Y.W.1
Chan, G.C.2
Kuo, C.T.3
Storm, D.R.4
Xia, Z.5
-
21
-
-
77950909970
-
Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart
-
PMID: 20075332
-
Kimura TE, Jin J, Zi M, Prehar S, Liu W, et al. (2010) Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart. Circ Res 106:961-970. doi: 10.1161/CIRCRESAHA.109.209320 PMID: 20075332
-
(2010)
Circ Res
, vol.106
, pp. 961-970
-
-
Kimura, T.E.1
Jin, J.2
Zi, M.3
Prehar, S.4
Liu, W.5
-
22
-
-
77956551578
-
Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein
-
PMID: 20832753
-
Yang Q, Deng X, Lu B, Cameron M, Fearns C, et al. (2010) Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein. Cancer Cell 18:258-267. doi: 10.1016/j.ccr.2010.08.008 PMID: 20832753
-
(2010)
Cancer Cell
, vol.18
, pp. 258-267
-
-
Yang, Q.1
Deng, X.2
Lu, B.3
Cameron, M.4
Fearns, C.5
-
23
-
-
33846782998
-
Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells
-
PMID: 17275785
-
Sharma G, Goalstone ML (2007) Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells. Biochem Biophys ResCommun 354:1078-1083. PMID: 17275785
-
(2007)
Biochem Biophys ResCommun
, vol.354
, pp. 1078-1083
-
-
Sharma, G.1
Goalstone, M.L.2
-
24
-
-
36048949007
-
Oncostatin M-induced effects on EMT in human proximal tubular cells: Differential role of ERK signaling
-
PMID: 17881458
-
Pollack V, Sarkozi R, Banki Z, Feifel E, Wehn S, et al. (2007) Oncostatin M-induced effects on EMT in human proximal tubular cells: differential role of ERK signaling. Am J Physiol Renal Physiol 293:F1714-1726. PMID: 17881458
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. F1714-F1726
-
-
Pollack, V.1
Sarkozi, R.2
Banki, Z.3
Feifel, E.4
Wehn, S.5
-
25
-
-
44849114794
-
ERK5/BMK1 is indispensable for optimal colony-stimulating factor 1 (CSF-1)-induced proliferation in macrophages in a Src-dependent fashion
-
PMID: 18322228
-
Rovida E, Spinelli E, Sdelci S, Barbetti V, Morandi A, et al. (2008) ERK5/BMK1 is indispensable for optimal colony-stimulating factor 1 (CSF-1)-induced proliferation in macrophages in a Src-dependent fashion. J Immunol 180:4166-4172. PMID: 18322228
-
(2008)
J Immunol
, vol.180
, pp. 4166-4172
-
-
Rovida, E.1
Spinelli, E.2
Sdelci, S.3
Barbetti, V.4
Morandi, A.5
-
26
-
-
77949912964
-
Erk5is necessary for sustained PDGF-induced Akt phosphorylation and inhibition of apoptosis
-
PMID: 20138986
-
Lennartsson J, Burovic F, Witek B, Jurek A, Heldin CH (2010) Erk5is necessary for sustained PDGF-induced Akt phosphorylation and inhibition of apoptosis. Cell Signal 22:955-960. doi: 10.1016/j. cellsig.2010.01.020 PMID: 20138986
-
(2010)
Cell Signal
, vol.22
, pp. 955-960
-
-
Lennartsson, J.1
Burovic, F.2
Witek, B.3
Jurek, A.4
Heldin, C.H.5
-
27
-
-
30044435224
-
Dominant negative FTase (DNFTalpha) inhibits ERK5, MEF2C and CREB activation in adipogenesis
-
PMID: 16356629
-
Sharma G, Goalstone ML (2005) Dominant negative FTase (DNFTalpha) inhibits ERK5, MEF2C and CREB activation in adipogenesis. Mol Cell Endocrinol 245:93-104. PMID: 16356629
-
(2005)
Mol Cell Endocrinol
, vol.245
, pp. 93-104
-
-
Sharma, G.1
Goalstone, M.L.2
-
28
-
-
33750447266
-
Neuroprotective role of ERK1/2 and ERK5 in a dopaminergic cell line under basal conditions and in response to oxidative stress
-
PMID: 16941494
-
Cavanaugh JE, Jaumotte JD, Lakoski JM, Zigmond MJ (2006) Neuroprotective role of ERK1/2 and ERK5 in a dopaminergic cell line under basal conditions and in response to oxidative stress. J Neurosci Res 84:1367-1375. PMID: 16941494
-
(2006)
J Neurosci Res
, vol.84
, pp. 1367-1375
-
-
Cavanaugh, J.E.1
Jaumotte, J.D.2
Lakoski, J.M.3
Zigmond, M.J.4
-
29
-
-
79961210010
-
ERK1/2 and ERK5 have distinct roles in the regulation of brain-derived neurotrophic factor expression
-
PMID: 21647938
-
Su C, Underwood W, Rybalchenko N, Singh M (2011) ERK1/2 and ERK5 have distinct roles in the regulation of brain-derived neurotrophic factor expression. J Neurosci Res 89:1542-1550. doi: 10.1002/jnr.22683 PMID: 21647938
-
(2011)
J Neurosci Res
, vol.89
, pp. 1542-1550
-
-
Su, C.1
Underwood, W.2
Rybalchenko, N.3
Singh, M.4
-
30
-
-
0033543549
-
Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus
-
PMID: 10473620
-
Kamakura S, Moriguchi T, Nishida E (1999) Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus. J Biol Chem 274:26563-26571. PMID: 10473620
-
(1999)
J Biol Chem
, vol.274
, pp. 26563-26571
-
-
Kamakura, S.1
Moriguchi, T.2
Nishida, E.3
-
31
-
-
0032524356
-
Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation
-
PMID: 9604935
-
Khokhlatchev AV, Canagarajah B, Wilsbacher J, Robinson M, Atkinson M, et al. (1998) Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation. Cell 93:605-615. PMID: 9604935
-
(1998)
Cell
, vol.93
, pp. 605-615
-
-
Khokhlatchev, A.V.1
Canagarajah, B.2
Wilsbacher, J.3
Robinson, M.4
Atkinson, M.5
-
32
-
-
0035815665
-
Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains
-
PMID: 11139578
-
Yan C, Luo H, Lee JD, Abe J, Berk BC (2001) Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains. J Biol Chem 276:10870-10878. PMID: 11139578
-
(2001)
J Biol Chem
, vol.276
, pp. 10870-10878
-
-
Yan, C.1
Luo, H.2
Lee, J.D.3
Abe, J.4
Berk, B.C.5
-
33
-
-
77956910145
-
Multisite phosphorylation of Erk5 in mitosis
-
PMID: 20736311
-
Diaz-Rodriguez E, Pandiella A (2010) Multisite phosphorylation of Erk5 in mitosis. J Cell Sci 123:3146-3156. doi: 10.1242/jcs.070516 PMID: 20736311
-
(2010)
J Cell Sci
, vol.123
, pp. 3146-3156
-
-
Diaz-Rodriguez, E.1
Pandiella, A.2
-
34
-
-
0030694387
-
BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C
-
PMID: 9384584
-
Kato Y, Kravchenko VV, Tapping RI, Han J, Ulevitch RJ, et al. (1997) BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C. Embo J 16:7054-7066. PMID: 9384584
-
(1997)
Embo J
, vol.16
, pp. 7054-7066
-
-
Kato, Y.1
Kravchenko, V.V.2
Tapping, R.I.3
Han, J.4
Ulevitch, R.J.5
-
35
-
-
33747792064
-
MAPK signalling: ERK5 versus ERK1/2
-
PMID: 16880823
-
Nishimoto S, Nishida E (2006) MAPK signalling: ERK5 versus ERK1/2. EMBO Rep 7:782-786. PMID: 16880823
-
(2006)
EMBO Rep
, vol.7
, pp. 782-786
-
-
Nishimoto, S.1
Nishida, E.2
-
36
-
-
13244291607
-
The unique C-terminal tail of the mitogen-activated protein kinase ERK5 regulates its activation and nuclear shuttling
-
PMID: 15548525
-
Buschbeck M, Ullrich A (2005) The unique C-terminal tail of the mitogen-activated protein kinase ERK5 regulates its activation and nuclear shuttling. J Biol Chem 280:2659-2667. PMID: 15548525
-
(2005)
J Biol Chem
, vol.280
, pp. 2659-2667
-
-
Buschbeck, M.1
Ullrich, A.2
-
37
-
-
33644537037
-
Regulation of nuclear translocation of extracellular signal-regulated kinase 5 by active nuclear import and export mechanisms
-
PMID: 16478989
-
Kondoh K, Terasawa K, Morimoto H, Nishida E (2006) Regulation of nuclear translocation of extracellular signal-regulated kinase 5 by active nuclear import and export mechanisms. Mol Cell Biol 26:1679-1690. PMID: 16478989
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1679-1690
-
-
Kondoh, K.1
Terasawa, K.2
Morimoto, H.3
Nishida, E.4
-
38
-
-
34447326686
-
Brain-derived neurotrophic factor stimulates the transcriptional and neuroprotective activity of myocyte-enhancer factor 2C through an ERK1/2-RSK2 signaling cascade
-
PMID: 17630987
-
Wang Y, Liu L, Xia Z (2007) Brain-derived neurotrophic factor stimulates the transcriptional and neuroprotective activity of myocyte-enhancer factor 2C through an ERK1/2-RSK2 signaling cascade. J Neurochem 102:957-966. PMID: 17630987
-
(2007)
J Neurochem
, vol.102
, pp. 957-966
-
-
Wang, Y.1
Liu, L.2
Xia, Z.3
-
39
-
-
0027165150
-
The mitogen-activated protein kinase signal transduction pathway
-
PMID: 8325833
-
Davis RJ (1993) The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268:14553-14556. PMID: 8325833
-
(1993)
J Biol Chem
, vol.268
, pp. 14553-14556
-
-
Davis, R.J.1
|