Colonic motor abnormalities in slow transit constipation defined by high resolution, fibre-optic manometry

Neurogastroenterology and Motility

Volumn 27, Issue 3, 2015, Pages 379-388

  Dinning, P G ^a,b   Wiklendt, L ^a   Maslen, L ^a   Patton, V ^b,c   Lewis, H ^a   Arkwright, J W ^a   Wattchow, D A ^a   Lubowski, D Z ^b,c   Costa, M ^a   Bampton, P A ^a  

^a FLINDERS UNIVERSITY   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c ST GEORGE HOSPITAL   (Australia)

Author keywords

Colonic pathophysiology; High resolution manometry; Slow transit constipation; Slow waves

Indexed keywords

ADULT; AGED; ANORECTAL PRESSURE; ARTICLE; CALORIC INTAKE; CLINICAL ARTICLE; COLON DISEASE; COLON MOTILITY; COLONIC CATHETER; COLONIC MOTOR ABNORMALITY; COLONOSCOPY; CONSTIPATION; CONTROLLED STUDY; DESCENDING COLON; FEMALE; FIBER OPTIC MANOMETRY; FIBEROPTIC MANOMETRY CATHETER; HUMAN; MALE; MANOMETRY; MEAL; POSTPRANDIAL STATE; PRIORITY JOURNAL; SENSOR; SIGMOID; COLON; FIBER OPTICS; GASTROINTESTINAL TRANSIT; MIDDLE AGED; PATHOPHYSIOLOGY; PROCEDURES; YOUNG ADULT;

ADULT; AGED; COLON; CONSTIPATION; FEMALE; FIBER OPTIC TECHNOLOGY; GASTROINTESTINAL TRANSIT; HUMANS; MALE; MANOMETRY; MIDDLE AGED; YOUNG ADULT;

EID: 84923264532     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/nmo.12502     Document Type: Article

References (54)

1. Bassotti G, Gaburri M, Imbimbo BP, Rossi L, Farroni F, Pelli MA, Morelli A. Colonic mass movements in idiopathic chronic constipation. Gut 1988; 29: 1173-9.
2. Rao SS, Sadeghi P, Beaty J, Kavlock R. Ambulatory 24-hour colonic manometry in slow-transit constipation. Am J Gastroenterol 2004; 99: 2405-16.
3. Di Lorenzo C, Flores AF, Reddy SN, Hyman PE. Use of colonic manometry to differentiate causes of intractable constipation in children. J Pediatr 1992; 120: 690-5.
4. Dinning PG, Zarate N, Hunt LM, Fuentealba SE, Mohammed SD, Szczesniak MM, Lubowski DZ, Preston SL et al. Pancolonic spatiotemporal mapping reveals regional deficiencies in, and disorganization of colonic propagating pressure waves in severe constipation. Neurogastroenterol Motil 2010; 22: e340-9.
5. Bassotti G, Villanacci V, Maurer CA, Fisogni S, Di Fabio F, Cadei M, Morelli A, Panagiotis T et al. The role of glial cells and apoptosis of enteric neurones in the neuropathology of intractable slow transit constipation. Gut 2006; 55: 41-6.
6. He C, Burgart L, Wang L, Pemberton J, Young-Fadok T, Szurszewski J, Farrugia G. Decreased interstitial cell of cajal volume in patients with slow-transit constipation. Gastroenterology 2000; 118: 14-21.
7. Farrugia G. Interstitial cells of Cajal in health and disease. Neurogastroenterol Motil 2008; 20(Suppl. 1): 54-63.
8. Lyford GL, He CL, Soffer E, Hull TL, Strong SA, Senagore AJ, Burgart LJ, Young-Fadok T et al. Pan-colonic decrease in interstitial cells of Cajal in patients with slow transit constipation. Gut 2002; 51: 496-501.
9. Porter AJ, Wattchow DA, Hunter A, Costa M. Abnormalities of nerve fibres in the circular muscle of patients with slow transit constipation. Int J Colorect Dis 1998; 13: 208-16.
10. Wattchow D, Brookes S, Murphy E, Carbone S, de Fontgalland D, Costa M. Regional variation in the neurochemical coding of the myenteric plexus of the human colon and changes in patients with slow transit constipation. Neurogastroenterol Motil 2008; 20: 1298-305.
11. Herve S, Savoye G, Behbahani A, Leroi AM, Denis P, Ducrotte P. Results of 24-h manometric recording of colonic motor activity with endoluminal instillation of bisacodyl in patients with severe chronic slow transit constipation. Neurogastroenterol Motil 2004; 16: 397-402.
12. Leroi AM, Lalaude O, Antonietti M, Touchais JY, Ducrotte P, Menard JF, Denis P. Prolonged stationary colonic motility recording in seven patients with severe constipation secondary to antidepressants. Neurogastroenterol Motil 2000; 12: 149-54.
13. De Schryver AM, Samsom M, Smout AI. Effects of a meal and bisacodyl on colonic motility in healthy volunteers and patients with slow-transit constipation. Dig Dis Sci 2003; 48: 1206-12.
14. Snape WJ, Wright SH, Battle WM, Cohen S. The gastrocolonic response: evidence for a neural mechanism. Gastroenterology 1979; 77: 1235-40.
15. Snape WJ, Matarazzo SA, Cohen S. Effect of eating and gastrointestinal hormones on human colonic myoelectrcal and motor activity. Gastroenterology 1978; 75: 373-8.
16. Wiley J, Tatum D, Keinath R, Chung OY. Participation of gastric mechanoreceptors and intestinal chemoreceptors in the gastrocolonic response. Gastroenterology 1988; 94: 1144-9.
17. Dinning PG, Wiklendt L, Maslen L, Gibbins I, Patton V, Arkwright JW, Lubowski DZ, O'Grady G et al. Quantification of in vivo colonic motor patterns in healthy humans before and after a meal revealed by high-resolution fibre-optic manometry. Neurgastroenterol Motil 2014; 26: 1442-57.
18. Singh S, Heady S, Coss-Adame E, Rao SS. Clinical utility of colonic manometry in slow transit constipation. Neurogastroenterol Motil 2013; 25: 487-95.
19. Bjornsson ES, Chey WD, Hooper F, Woods ML, Owyang C, Hasler WL. Impaired gastrocolonic reponse and peristaltic reflex in slow transit constipation: role of 5HT3 pathways. Am J Physiol Gastrointest Liver Physiol 2002; 283: G400-7.
20. Knowles CH, Thin N, Gill K, Bhan C, Grimmer K, Lunniss PJ, Williams NS, Scott SM. Prospective randomized double-blind study of temporary sacral nerve stimulation in patients with rectal evacuatory dysfunction and rectal hyposensitivity. Ann Surg 2012; 255: 643-9.
21. Sullivan MA, Cohen S, Snape WJ Jr. Colonic myoelectrical activity in irritable-bowel syndrome. Effect of eating and anticholinergics. N Engl J Med 1978; 298: 878-83.
22. Wright SH, Snape WJ Jr, Battle W, Cohen S, London RL. Effect of dietary components on gastrocolonic response. Am J Physiol 1980; 238: G228-32.
23. Bassotti G, Betti C, Imbimbo BP, Pelli MA, Morelli A. Colonic motor response to eating: a manometric investigation in proximal and distal portions of the viscus in man. Am J Gastroenterol 1989; 84: 118-22.
24. Rao SS, Kavelock R, Beaty J, Ackerson K, Stumbo P. Effects of fat and carbohydrate meals on colonic motor response. Gut 2000; 46: 205-11.
25. Bjornsson ES, Chey WD, Ladabaum U, Woods ML, Hooper FG, Owyang C, Hasler WL. Differential 5-HT3 mediation of human gastrocolonic response and colonic peristaltic reflex. Am J Physiol 1998; 275: G498-505.
26. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, Cook IJ. Prolonged multi-point recording of colonic manometry in the unprepared human colon: providing insight into potentially relevant pressure wave parameters. Am J Gastroenterol 2001; 96: 1838-48.
27. Dinning PG, Wiklendt L, Gibbins I, Patton V, Bampton PA, Lubowski DZ, Cook IJ, Arkwright JW. Low-resolution colonic manometry leads to a gross mis-interpretation of the frequency and polarity of propagating sequences: initial results from fibre-optic high-resolution manometry studies. Neurogastroenterol Motil 2013; 25: e640-9.
28. Patton V, Wiklendt L, Arkwright JW, Lubowski DZ, Dinning PG. The effect of sacral nerve stimulation on distal colonic motility in patients with faecal incontinence. Br J Surg 2013; 100: 959-68.
29. Dinning PG, Hunt L, Arkwright JW, Patton V, Szczesniak MM, Wiklendt L, Davidson JB, Lubowski DZ et al. Pancolonic motor response to subsensory and suprasensory sacral nerve stimulation in patients with slow-transit constipation. Br J Surg 2012; 99: 1002-10.
30. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006; 130: 1480-91.
31. McLean RG, Smart RC, Lubowski DZ, King DW, Barbagallo S, Talley NA. Oral colon transit scintigraphy using Indium-111 DTPA: variability in healthy subjects. Int J Colorectal Dis 1992; 7: 173-6.
32. Simpson RR, Kennedy ML, Nguyen MH, Dinning PG, Lubowski DZ. Anal manometry: a comparison of techniques. Dis Colon Rectum 2006; 49: 1033-8.
33. Arkwright JW, Underhill ID, Maunder SA, Blenman N, Szczesniak MM, Wiklendt L, Cook IJ, Lubowski DZ et al. Design of a high-sensor count fibre optic manometry catheter for in-vivo colonic diagnostics. Opt Express 2009; 17: 22423-31.
34. Dinning PG, Fuentealba SE, Kennedy ML, Lubowski DZ, Cook IJ. Sacral nerve stimulation induces pan-colonic propagating pressure waves and increases defecation frequency in patients with slow-transit constipation. Colorectal Dis 2007; 9: 123-32.
35. Wiklendt L, Mohammed SD, Scott SM, Dinning PG. Classification of normal and abnormal colonic motility based on cross-correlations of pancolonic manometry data. Neurogastroenterol Motil 2013; 25: e215-23.
36. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, deCarle D, Cook IJ. Spatial and temporal organization of pressure patterns throughout the unprepared colon during spontaneous defecation. Am J Gastroenterol 2000; 95: 1027-35.
37. Jones E, Oliphant T, Peterson P. SciPy: Open source scientific tools for Python, 2001-2008. Available at: http://www.scipy.org.
38. Gilks WR, Richardson S, Spiegelhalter DJ. Markov Chain Monte Carlo in Practice. London: Chapman and Hall, 1996.
39. Lange KL, Little RJA, Taylor JMG. Robust statistical modeling using the t distribution. Journal of the American Statistical Association 1989; 84: 881-96.
40. Meredith M, Kruschke J. K. Bayesian estimation supersedes the t test. J Exp Psychol Gen 2013; 142: 573-603.
41. Hertz AF, Newton A. The normal movements of the colon in man. J Physiol 1913; 47: 57-65.
42. Rao SS, Sadeghi P, Beaty J, Kavlock R, Ackerson K. Ambulatory 24-h colonic manometry in healthy humans. Am J Physiol Gastrointest Liver Physiol 2001; 280: G629-39.
43. Bassotti G, Gaburri M. Manometric investigation of high-amplitude propagated contractile activity of the human colon. Am J Physiol 1988; 255: G660-4.
44. Welch PB, Plant OH. A graphic study of the muscular activity of the colon, with special reference to its response to feeding. Am J Med Sci 1926; 172: 261-8.
45. Kumar D, Williams NS, Waldron D, Wingate DL. Prolonged manometric recording of anorectal motor activity in ambulant human subjects: evidence of periodic activity. Gut 1989; 30: 1007-11.
46. Rao SS, Welcher K. Periodic rectal motor activity: the intrinsic colonic gatekeeper? Am J Gastroenterol 1996; 91: 890-7.
47. Rae MG, Fleming N, McGregor DB, Sanders KM, Keef KD. Control of motility patterns in the human colonic circular muscle layer by pacemaker activity. J Physiol 1998; 510(Pt 1): 309-20.
48. Carbone SE, Dinning PG, Costa M, Spencer NJ, Brookes SJ, Wattchow DA. Ascending excitatory neural pathways modulate slow phasic myogenic contractions in the isolated human colon. Neurogastroenterol Motil 2013; 25: 670-6.
49. Costa M, Wiklendt L, Arkwright JW, Spencer NJ, Omari T, Brookes SJ, Dinning PG. An experimental method to identify neurogenic and myogenic active mechanical states of intestinal motility. Front Syst Neurosci 2013; 7: 7.
50. Huizinga JD, Martz S, Gil V, Wang XY, Jimenez M, Parsons S. Two independent networks of interstitial cells of cajal work cooperatively with the enteric nervous system to create colonic motor patterns. Front Neurosci 2011; 5: 93.
51. Sanders KM, Koh SD, Ward SM. Interstitial cells of Cajal as pacemakers in the gastrointestinal tract. Ann Review Physiol 2006; 68: 307-43.
52. Aaronson MJ, Freed MM, Burakoff R. Colonic myoelectric activity in persons with spinal cord injury. Dig Dis Sci 1985; 30: 295-300.
53. O'Grady G, Angeli TR, Du P, Lahr C, Lammers WJ, Windsor JA, Abell TL, Farrugia G et al. Abnormal initiation and conduction of slow-wave activity in gastroparesis, defined by high-resolution electrical mapping. Gastroenterology 2012; 143: 589-98, e581-583.
54. Di Lorenzo C, Flores AF, Reddy SN, Snape WJ, Bazzochi G, Hyman PE. Colonic manometry in children with chronic intestinal pseudo-obstruction. Gut 1993; 34: 803-7.