-
1
-
-
0002352160
-
Chronic lymphocytic leukemia, epidemiological, familial, and genetic aspects
-
Second Edition, Revised and Expanded, ed Cheson B (Marcel Dekker, New York)
-
Sgambati M, Linet M, Devesa S (2001) Chronic Lymphocytic Leukemia, Epidemiological, Familial, and Genetic Aspects. Chronic Lymphocytic Leukemias, Second Edition, Revised and Expanded, ed Cheson B (Marcel Dekker, New York) pp. 33-62.
-
(2001)
Chronic Lymphocytic Leukemias
, pp. 33-62
-
-
Sgambati, M.1
Linet, M.2
Devesa, S.3
-
2
-
-
84870763388
-
High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations
-
Edelmann J, et al. (2012) High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations. Blood 120(24):4783-4794.
-
(2012)
Blood
, vol.120
, Issue.24
, pp. 4783-4794
-
-
Edelmann, J.1
-
3
-
-
0034727833
-
Genomic aberrations and survival in chronic lymphocytic leukemia
-
Döhner H, et al. (2000) Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 343(26):1910-1916.
-
(2000)
N Engl J Med
, vol.343
, Issue.26
, pp. 1910-1916
-
-
Döhner, H.1
-
4
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, et al. (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99(24):15524-15529.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.24
, pp. 15524-15529
-
-
Calin, G.A.1
-
5
-
-
42449152333
-
MiR-15a and miR-16-1 cluster functions in human leukemia
-
Calin GA, et al. (2008) MiR-15a and miR-16-1 cluster functions in human leukemia. Proc Natl Acad Sci USA 105(13):5166-5171.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.13
, pp. 5166-5171
-
-
Calin, G.A.1
-
6
-
-
33846190181
-
Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181
-
Pekarsky Y, et al. (2006) Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res 66(24):11590-11593.
-
(2006)
Cancer Res
, vol.66
, Issue.24
, pp. 11590-11593
-
-
Pekarsky, Y.1
-
7
-
-
80052939685
-
MiR-181b is a biomarker of disease progression in chronic lymphocytic leukemia
-
Visone R, et al. (2011) miR-181b is a biomarker of disease progression in chronic lymphocytic leukemia. Blood 118(11):3072-3079.
-
(2011)
Blood
, vol.118
, Issue.11
, pp. 3072-3079
-
-
Visone, R.1
-
9
-
-
31444446831
-
TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state
-
Herling M, et al. (2006) TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state. Leukemia 20(2):280-285.
-
(2006)
Leukemia
, vol.20
, Issue.2
, pp. 280-285
-
-
Herling, M.1
-
10
-
-
23144442026
-
The TCL1 family of oncoproteins: Co-activators of transformation
-
Teitell MA (2005) The TCL1 family of oncoproteins: Co-activators of transformation. Nat Rev Cancer 5(8):640-648.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.8
, pp. 640-648
-
-
Teitell, M.A.1
-
11
-
-
0037076279
-
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression
-
Bichi R, et al. (2002) Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression. Proc Natl Acad Sci USA 99(10):6955-6960.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.10
, pp. 6955-6960
-
-
Bichi, R.1
-
12
-
-
77952424509
-
CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation
-
Efanov A, et al. (2010) CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation. Leukemia 24(5): 970-975.
-
(2010)
Leukemia
, vol.24
, Issue.5
, pp. 970-975
-
-
Efanov, A.1
-
13
-
-
33746817989
-
B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia
-
Yan XJ, et al. (2006) B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia. Proc Natl Acad Sci USA 103(31):11713-11718.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.31
, pp. 11713-11718
-
-
Yan, X.J.1
-
14
-
-
73349098730
-
Chronic lymphocytic leukemia of Emu-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression
-
Enzler T, et al. (2009) Chronic lymphocytic leukemia of Emu-TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression. Blood 114(20):4469-4476.
-
(2009)
Blood
, vol.114
, Issue.20
, pp. 4469-4476
-
-
Enzler, T.1
-
16
-
-
78149309123
-
HS1 has a central role in the trafficking and homing of leukemic B cells
-
Scielzo C, et al. (2010) HS1 has a central role in the trafficking and homing of leukemic B cells. Blood 116(18):3537-3546.
-
(2010)
Blood
, vol.116
, Issue.18
, pp. 3537-3546
-
-
Scielzo, C.1
-
17
-
-
84863529042
-
Novel insights in molecular mechanisms of CLL
-
Zanesi N, Balatti V, Bottoni A, Croce CM, Pekarsky Y (2012) Novel insights in molecular mechanisms of CLL. Curr Pharm Des 18(23):3363-3372.
-
(2012)
Curr Pharm des
, vol.18
, Issue.23
, pp. 3363-3372
-
-
Zanesi, N.1
Balatti, V.2
Bottoni, A.3
Croce, C.M.4
Pekarsky, Y.5
-
18
-
-
0034724199
-
Tcl1 enhances Akt kinase activity and mediates its nuclear translocation
-
Pekarsky Y, et al. (2000) Tcl1 enhances Akt kinase activity and mediates its nuclear translocation. Proc Natl Acad Sci USA 97(7):3028-3033.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.7
, pp. 3028-3033
-
-
Pekarsky, Y.1
-
19
-
-
58149376457
-
Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL
-
Pekarsky Y, et al. (2008) Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL. Proc Natl Acad Sci USA 105(50):19643-19648.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.50
, pp. 19643-19648
-
-
Pekarsky, Y.1
-
20
-
-
84863138658
-
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)
-
Palamarchuk A, et al. (2012) Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL). Proc Natl Acad Sci USA 109(7):2555-2560.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.7
, pp. 2555-2560
-
-
Palamarchuk, A.1
-
21
-
-
84904011188
-
Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia
-
Claus R, et al. (2014) Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia. Blood 124(1):42-48.
-
(2014)
Blood
, vol.124
, Issue.1
, pp. 42-48
-
-
Claus, R.1
-
22
-
-
79951568817
-
Discovery of novel human breast cancer microRNAs from deep sequencing data by analysis of pri-microRNA secondary structures
-
Ryu S, et al. (2011) Discovery of novel human breast cancer microRNAs from deep sequencing data by analysis of pri-microRNA secondary structures. PLoS ONE 6(2): e16403.
-
(2011)
PLoS ONE
, vol.6
, Issue.2
, pp. e16403
-
-
Ryu, S.1
-
23
-
-
84864071185
-
Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia
-
Claus R, et al. (2012) Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia. J Clin Oncol 30(20):2483-2491.
-
(2012)
J Clin Oncol
, vol.30
, Issue.20
, pp. 2483-2491
-
-
Claus, R.1
-
24
-
-
77955435090
-
Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression
-
Santanam U, et al. (2010) Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression. Proc Natl Acad Sci USA 107(27):12210-12215.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.27
, pp. 12210-12215
-
-
Santanam, U.1
-
25
-
-
25444520537
-
MiR-15 and miR-16 induce apoptosis by targeting BCL2
-
Cimmino A, et al. (2005) miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102(39):13944-13949.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.39
, pp. 13944-13949
-
-
Cimmino, A.1
-
26
-
-
56549129538
-
Chromatin structure analyses identify miRNA promoters
-
Ozsolak F, et al. (2008) Chromatin structure analyses identify miRNA promoters. Genes Dev 22(22):3172-3183.
-
(2008)
Genes Dev
, vol.22
, Issue.22
, pp. 3172-3183
-
-
Ozsolak, F.1
-
28
-
-
77952988986
-
Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells
-
Canella D, Praz V, Reina JH, Cousin P, Hernandez N (2010) Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells. Genome Res 20(6):710-721.
-
(2010)
Genome Res
, vol.20
, Issue.6
, pp. 710-721
-
-
Canella, D.1
Praz, V.2
Reina, J.H.3
Cousin, P.4
Hernandez, N.5
-
29
-
-
66149187105
-
Transcription termination by nuclear RNA polymerases
-
Richard P, Manley JL (2009) Transcription termination by nuclear RNA polymerases. Genes Dev 23(11):1247-1269.
-
(2009)
Genes Dev
, vol.23
, Issue.11
, pp. 1247-1269
-
-
Richard, P.1
Manley, J.L.2
-
30
-
-
79954999804
-
Understanding and managing ultra high-risk chronic lymphocytic leukemia
-
Stilgenbauer S, Zenz T (2010) Understanding and managing ultra high-risk chronic lymphocytic leukemia. Hematology (Am Soc Hematol Educ Program) 2010:481-488.
-
(2010)
Hematology (Am Soc Hematol Educ Program)
, vol.2010
, pp. 481-488
-
-
Stilgenbauer, S.1
Zenz, T.2
-
31
-
-
84882602512
-
Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment
-
Hallek M (2013) Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment. Am J Hematol 88(9):803-816.
-
(2013)
Am J Hematol
, vol.88
, Issue.9
, pp. 803-816
-
-
Hallek, M.1
-
32
-
-
84934442378
-
TP53 aberrations in chronic lymphocytic leukemia
-
Trbusek M, Malcikova J (2013) TP53 aberrations in chronic lymphocytic leukemia. Adv Exp Med Biol 792:109-131.
-
(2013)
Adv Exp Med Biol
, vol.792
, pp. 109-131
-
-
Trbusek, M.1
Malcikova, J.2
-
33
-
-
52249091511
-
Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic leukemia
-
Gunn SR, et al. (2008) Whole-genome scanning by array comparative genomic hybridization as a clinical tool for risk assessment in chronic lymphocytic leukemia. J Mol Diagn 10(5):442-451.
-
(2008)
J Mol Diagn
, vol.10
, Issue.5
, pp. 442-451
-
-
Gunn, S.R.1
-
34
-
-
77950202393
-
Human tRNA-derived small RNAs in the global regulation of RNA silencing
-
Haussecker D, et al. (2010) Human tRNA-derived small RNAs in the global regulation of RNA silencing. RNA 16(4):673-695.
-
(2010)
RNA
, vol.16
, Issue.4
, pp. 673-695
-
-
Haussecker, D.1
-
35
-
-
72749089855
-
A novel class of small RNAs: TRNAderived RNA fragments (tRFs)
-
Lee YS, Shibata Y, Malhotra A, Dutta A (2009) A novel class of small RNAs: tRNAderived RNA fragments (tRFs). Genes Dev 23(22):2639-2649.
-
(2009)
Genes Dev
, vol.23
, Issue.22
, pp. 2639-2649
-
-
Lee, Y.S.1
Shibata, Y.2
Malhotra, A.3
Dutta, A.4
-
36
-
-
84891849709
-
Loss of p53 and altered miR15-A/16-1 MCL-1 pathway in CLL: Insights from TCL1-Tg:p53(-/-) mouse model and primary human leukemia cells
-
Liu J, et al. (2014) Loss of p53 and altered miR15-a/16-1 MCL-1 pathway in CLL: insights from TCL1-Tg:p53(-/-) mouse model and primary human leukemia cells. Leukemia 28(1):118-128.
-
(2014)
Leukemia
, vol.28
, Issue.1
, pp. 118-128
-
-
Liu, J.1
-
37
-
-
84888440844
-
B cell receptor signaling in chronic lymphocytic leukemia
-
Burger JA, Chiorazzi N (2013) B cell receptor signaling in chronic lymphocytic leukemia. Trends Immunol 34(12):592-601.
-
(2013)
Trends Immunol
, vol.34
, Issue.12
, pp. 592-601
-
-
Burger, J.A.1
Chiorazzi, N.2
-
38
-
-
84863011553
-
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo
-
Ponader S, et al. (2012) The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Blood 119(5):1182-1189.
-
(2012)
Blood
, vol.119
, Issue.5
, pp. 1182-1189
-
-
Ponader, S.1
-
39
-
-
27244434788
-
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
-
Calin GA, et al. (2005) A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 353(17):1793-1801.
-
(2005)
N Engl J Med
, vol.353
, Issue.17
, pp. 1793-1801
-
-
Calin, G.A.1
-
40
-
-
84891882468
-
Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia
-
Allegra D, et al. (2014) Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia. Leukemia 28(1):98-107.
-
(2014)
Leukemia
, vol.28
, Issue.1
, pp. 98-107
-
-
Allegra, D.1
|