Pathophysiology and aetiology of obesity

Medicine (United Kingdom)

Volumn 43, Issue 2, 2015, Pages 73-76

  Baqai, Najah ^a   Wilding, John P H ^b  

^a ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Appetite; genetics; ghrelin; hypothalamus; leptin; metabolic rate; obesity Prader Willi syndrome; pro opiomelanocortin satiety

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; INSULIN; MELANOCORTIN 4 RECEPTOR; NEUROLEPTIC AGENT; ORAL ANTIDIABETIC AGENT; PROOPIOMELANOCORTIN; PROTEINASE INHIBITOR; SEX HORMONE;

ADENOMA; APPETITE; ARTICLE; BASAL METABOLIC RATE; BODY MASS; CALORIC INTAKE; CENTRAL NERVOUS SYSTEM; CHILDHOOD OBESITY; DISEASE SEVERITY; EATING DISORDER; ENDOCRINE DISEASE; ENERGY BALANCE; ENERGY EXPENDITURE; FAILURE TO THRIVE; FOOD INTAKE; GENE MUTATION; GENETIC DISORDER; GENETIC SUSCEPTIBILITY; HUMAN; HYPERPHAGIA; HYPOTHALAMUS; LEPTIN DEFICIENCY; LIFESTYLE; METABOLIC RATE; METABOLIC REGULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OVARY POLYCYSTIC DISEASE; PATHOPHYSIOLOGY; PHYSICAL ACTIVITY; PHYSICAL INACTIVITY; PRIORITY JOURNAL; RISK FACTOR; SHORT STATURE; WEIGHT GAIN;

EID: 84923193826     PISSN: 13573039     EISSN: 13654357     Source Type: Journal    
DOI: 10.1016/j.mpmed.2014.11.016     Document Type: Review

References (11)

1. G. Whitlock, S. Lewington, and P. Sherliker Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies Lancet 373 2009 1083 1096
2. R.J. Hancox, B.J. Milne, and R. Poulton Association between child and adolescent television viewing and adult health: a longitudinal birth cohort study Lancet 364 2004 257 262
3. M.A. Pereira, A.I. Kartashov, and C.B. Ebbeling Fast-food habits, weight gain, and insulin resistance (the CARDIA study): 15-year prospective analysis Lancet 365 2005 36 42
4. K.A. Fawcett, and I. Barroso The genetics of obesity: FTO leads the way Trends Genet 26 2010 266 274
5. I. Sadaf Farooqi Defining the neural basis of appetite and obesity: from genes to behaviour Clin Med 14 2014 286 289
6. Foresight. Tackling obesities: future choices-project report. Available from: http://www.bis.gov.uk/assets/bispartners/foresight/docs/obesity/ 17.pdf (accessed 5 Oct 2010).
7. T.J. Frayling Are the causes of obesity primarily environmental? No BMJ 345 2012 http://dx.doi.org/10.1136/bmj.e5844
8. K.D. Hall, G. Sacks, and D. Chandramohan Quantification of the effect of energy imbalance on bodyweight Lancet 378 2011 826 837
9. M. Huda, J.P.H. Wilding, and J.H. Pinkney Gut peptides in the regulation of appetite Obes Rev 7 2006 163 182
10. J.P.H. Wilding BMJ debate head to head: the causes of obesity are largely environmental: yes BMJ 345 2012 http://dx.doi.org/10.1136/bmj.e5843
11. G. Williams, and G. Fruhbeck Obesity: science and practice 2009 Wiley Oxford