Each small antral follicle in ovaries of women with polycystic ovary syndrome produces more antimüllerian hormone than its counterpart in a normal ovary: An observational cross-sectional study

Fertility and Sterility

Volumn 103, Issue 2, 2015, Pages 537-541

  Bhide, Priya ^a   Dilgil, Merve ^a   Gudi, Anil ^a   Shah, Amit ^a   Akwaa, Charity ^a   Homburg, Roy ^a  

^a HOMERTON UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Antimuullerian hormone (AMH); antral follicle count (AFC); polycystic ovarian morphology (PCOM); polycystic ovarian syndrome (PCOS)

Indexed keywords

MUELLERIAN INHIBITING FACTOR; BIOLOGICAL MARKER;

ADULT; ARTICLE; BODY MASS; CELL COUNT; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; IN VIVO STUDY; MAJOR CLINICAL STUDY; MORPHOLOGY; OBSERVATIONAL STUDY; OVARY FOLLICLE CELL; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROTEIN SECRETION; SMOKING; BLOOD; COMPARATIVE STUDY; INFERTILITY, FEMALE; METABOLISM; OVARY; OVARY FOLLICLE; POLYCYSTIC OVARY SYNDROME;

ADULT; ANTI-MULLERIAN HORMONE; BIOLOGICAL MARKERS; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INFERTILITY, FEMALE; OVARIAN FOLLICLE; OVARY; POLYCYSTIC OVARY SYNDROME;

EID: 84923190463     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2014.10.033     Document Type: Article

References (21)

1. L.J. Webber, S. Stubbs, J. Stark, G.H. Trew, R. Margara, and K. Hardy Formation and early development of follicles in the polycystic ovary Lancet 362 2003 1017 1021
2. C.L. Cook, Y. Siow, A.G. Brenner, and M.E. Fallat Relationship between serum müllerian-inhibiting substance and other reproductive hormones in untreated women with polycystic ovarian syndrome and normal women Fertil Steril 77 2002 141 146
3. J.S. Laven, A.M. Mulders, J. Visser, A.P. Themmen, F.H. de Jong, and B.C. Fauser Anti-müllerian hormone serum concentrations in normoovulatory and anovulatory women of reproductive age J Clin Endocrinol Metab 89 2004 318 323
4. P. Pigny, S. Jonard, Y. Robert, and D. Dewailly Serum antimüllerian hormone as a surrogate marker for antral follicle count for definition of the polycystic ovarian syndrome J Clin Endocrinol Metab 91 2006 941 945
5. R. Homburg, A. Ray, P. Bhide, A. Gudi, A. Shah, and P. Timms The relationship of serum anti-müllerian hormone with polycystic ovarian morphology and polycystic ovary syndrome: a prospective cohort study Hum Reprod 28 2013 1077 1083
6. C. Weenen, J.S. Laven, A.R. von Bergh, M. Cranfield, N.P. Groome, and J.A. Visser Anti-müllerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment Mol Hum Reprod 10 2004 77 83
7. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome Fertil Steril 81 2004 19 25
8. A. la Marca, G. Stabile, A.C. Artenisio, and A. Volpe Serum anti-müllerian hormone throughout the human menstrual cycle Hum Reprod 21 2006 3103 3107
9. I. Streuli, T. Fraisse, C. Pillet, V. Ibecheole, P. Bischof, and D. de Ziegler Serum antimüllerian hormone levels remain stable throughout the menstrual cycle and after oral or vaginal administration of synthetic sex steroids Fertil Steril 90 2008 395 400
10. K. Jayaprakasan, B.K. Campbell, J.S. Clewes, I.R. Johnson, and N.J. Raine-Fenning Three-dimensional ultrasound improves the interobserver reliability of antral follicle counts and facilitates increased clinical work flow Ultrasound Obstet Gynecol 31 2008 439 444
11. H.I. Su, M.D. Sammel, E.W. Freeman, H. Lin, T. DeBlasis, and C.R. Gracia Body size affects measures of ovarian reserve in late reproductive age women Menopause 15 2008 857 861
12. T. Freour, D. Masson, S. Mirallie, M. Jean, K. Bach, and T. Dejoie Active smoking compromises IVF outcome and affects ovarian reserve Reprod Biomed Online 16 2008 96 102
13. L. Pellatt, L. Hanna, M. Brincat, R. Galea, H. Brain, and S. Whitehead Granulosa cell production of anti-müllerian hormone is increased in polycystic ovaries J Clin Endocrinol Metab 92 2007 240 245
14. S. Catteau-Jonard, S.P. Jamin, A. Leclerc, J. Gonzales, D. Dewailly, and N. di Clemente Anti-müllerian hormone, its receptor, FSH receptor and androgen receptor genes are overexpressed by granulosa cells from stimulated follicles in women with polycystic ovary syndrome J Clin Endocrinol Metab 93 2008 4456 4461
15. J.V. Jeppesen, R.A. Anderson, T.W. Kelsey, S.L. Christiansen, S.G. Kristensen, and K. Jayaprakasan Which follicles make the most anti-müllerian hormone in humans? Evidence for an abrupt decline in AMH production at the time of follicle selection Mol Hum Reprod 19 2013 519 527
16. L. Pellatt, S. Rice, N. Dilaver, A. Heshri, R. Galea, and M. Brincat Anti-müllerian hormone reduces follicle sensitivity to follicle-stimulating hormone in human granulosa cells Fertil Steril 96 2011 1246 1251
17. Pellatt L, Rice S, Brincat M, Galea R, Mason H. Anti-müllerian hormone (AMH) inhibits aromatase expression in granulosa cells from human ovaries. Proceedings of the Endocrine Society USA, 89th Annual Meeting, Toronto, Canada; 2007. Oral presentation 48-4.
18. N. di Clemente, B. Goxe, J. Remmy, R. Cate, N. Josso, and B. Vigier Inhibitory effect of MAH upon the expression of aromatase and LH receptors by cultured granulose cells of rat and porcine immature ovaries Endocrine 2 1994 553 558
19. T. Eldar-Geva, E.J. Margalioth, M. Gai, A. Ben-Chetrit, N. Algur, and E. Zylber-Haran Serum anti-müllerian hormone levels during controlled ovarian hyperstimulation in women in polycystic ovaries with and without hyperandrogenism Hum Reprod 20 2005 1814 1819
20. A. La Marca, R. Orvieto, S. Giulini, V.M. Jasonni, A. Volpe, and V. de Leo Müllerian-inhibiting substance in women with polycystic ovary syndrome: relationship with hormonal and metabolic characteristics Fertil Steril 82 2004 970 972
21. S.M. Carlsen, E. Vanky, and R. Fleming Anti-müllerian hormone concentrations in androgen-suppressed women with polycystic ovary syndrome Hum Reprod 24 2009 1732 1738