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Volumn 33, Issue 6, 2015, Pages 651-653

Are all chimeric antigen receptors created equal?

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; FC RECEPTOR; IMMUNOGLOBULIN; T LYMPHOCYTE RECEPTOR; ANTINEOPLASTIC AGENT; CD19 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84923123144     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2014.57.5472     Document Type: Article
Times cited : (21)

References (26)
  • 1
    • 84923118622 scopus 로고    scopus 로고
    • Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor
    • Kochenderfer JN, Dudley ME, Kassim SH, et al: Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor. J Clin Oncol 33:540-549, 2015
    • (2015) J Clin Oncol , vol.33 , pp. 540-549
    • Kochenderfer, J.N.1    Dudley, M.E.2    Kassim, S.H.3
  • 2
    • 78549278144 scopus 로고    scopus 로고
    • Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
    • Kochenderfer JN, Wilson WH, Janik JE, et al: Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19. Blood 116:4099-4102, 2010
    • (2010) Blood , vol.116 , pp. 4099-4102
    • Kochenderfer, J.N.1    Wilson, W.H.2    Janik, J.E.3
  • 3
    • 84863337890 scopus 로고    scopus 로고
    • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
    • Kochenderfer JN, Dudley ME, Feldman SA, et al: B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 119:2709-2720, 2012
    • (2012) Blood , vol.119 , pp. 2709-2720
    • Kochenderfer, J.N.1    Dudley, M.E.2    Feldman, S.A.3
  • 4
    • 84923170365 scopus 로고    scopus 로고
    • T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukemia in children and young adults: A phase I dose-escalation trial
    • epub ahead of print on October 10, 2014
    • Lee DW, Kochenderfer JN, Stetler-Stevenson M, et al: T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukemia in children and young adults: A phase I dose-escalation trial. Lancet [epub ahead of print on October 10, 2014]
    • Lancet
    • Lee, D.W.1    Kochenderfer, J.N.2    Stetler-Stevenson, M.3
  • 5
    • 80455179612 scopus 로고    scopus 로고
    • Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
    • Brentjens RJ, Rivière I, Park JH, et al: Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 118:4817-4828, 2011
    • (2011) Blood , vol.118 , pp. 4817-4828
    • Brentjens, R.J.1    Rivière, I.2    Park, J.H.3
  • 6
    • 84876005284 scopus 로고    scopus 로고
    • CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
    • Brentjens RJ, Davila ML, Riviere I, et al: CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 5:177ra138, 2013
    • (2013) Sci Transl Med , vol.5 , pp. 177ra138
    • Brentjens, R.J.1    Davila, M.L.2    Riviere, I.3
  • 7
    • 84896335556 scopus 로고    scopus 로고
    • Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
    • Davila ML, Riviere I, Wang X, et al: Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia. Sci Transl Med 6:224ra225, 2014
    • (2014) Sci Transl Med , vol.6 , pp. 224ra225
    • Davila, M.L.1    Riviere, I.2    Wang, X.3
  • 8
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, et al: Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med 365:725-733, 2011
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3
  • 9
    • 84876325876 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
    • Grupp SA, Kalos M, Barrett D, et al: Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med 368:1509-1518, 2013
    • (2013) N Engl J Med , vol.368 , pp. 1509-1518
    • Grupp, S.A.1    Kalos, M.2    Barrett, D.3
  • 10
    • 80051775476 scopus 로고    scopus 로고
    • T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
    • Kalos M, Levine BL, Porter DL, et al: T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 3:95ra73, 2011
    • (2011) Sci Transl Med , vol.3 , pp. 95ra73
    • Kalos, M.1    Levine, B.L.2    Porter, D.L.3
  • 11
    • 84908073316 scopus 로고    scopus 로고
    • Chimeric antigen receptor T cells for sustained remissions in leukemia
    • Maude SL, Frey N, Shaw PA, et al: Chimeric antigen receptor T cells for sustained remissions in leukemia. N Engl J Med 371:1507-1517, 2014
    • (2014) N Engl J Med , vol.371 , pp. 1507-1517
    • Maude, S.L.1    Frey, N.2    Shaw, P.A.3
  • 12
    • 0037441593 scopus 로고    scopus 로고
    • T-cell clones can be rendered specific for CD19: Toward the selective augmentation of the graft-versus-B-lineage leukemia effect
    • Cooper LJ, Topp MS, Serrano LM, et al: T-cell clones can be rendered specific for CD19: toward the selective augmentation of the graft-versus-B-lineage leukemia effect. Blood 101:1637-1644, 2003
    • (2003) Blood , vol.101 , pp. 1637-1644
    • Cooper, L.J.1    Topp, M.S.2    Serrano, L.M.3
  • 13
    • 0028902765 scopus 로고
    • Signals through T cell receptor-zeta chain alone are insufficient to prime resting T lymphocytes
    • Brocker T, Karjalainen K: Signals through T cell receptor-zeta chain alone are insufficient to prime resting T lymphocytes. J Exp Med 181:1653-1659, 1995
    • (1995) J Exp Med , vol.181 , pp. 1653-1659
    • Brocker, T.1    Karjalainen, K.2
  • 14
    • 0037348324 scopus 로고    scopus 로고
    • Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15
    • Brentjens RJ, Latouche JB, Santos E, et al: Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15. Nat Med 9:279-286, 2003
    • (2003) Nat Med , vol.9 , pp. 279-286
    • Brentjens, R.J.1    Latouche, J.B.2    Santos, E.3
  • 15
    • 34848842554 scopus 로고    scopus 로고
    • Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts
    • Brentjens RJ, Santos E, Nikhamin Y, et al: Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts. Clin Cancer Res 13:5426-5435, 2007
    • (2007) Clin Cancer Res , vol.13 , pp. 5426-5435
    • Brentjens, R.J.1    Santos, E.2    Nikhamin, Y.3
  • 16
    • 50549096284 scopus 로고    scopus 로고
    • Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells
    • Till BG, Jensen MC, Wang J, et al: Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells. Blood 112:2261-2271, 2008
    • (2008) Blood , vol.112 , pp. 2261-2271
    • Till, B.G.1    Jensen, M.C.2    Wang, J.3
  • 17
    • 70350726110 scopus 로고    scopus 로고
    • Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo
    • Milone MC, Fish JD, Carpenito C, et al: Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo. Mol Ther 17:1453-1464, 2009
    • (2009) Mol Ther , vol.17 , pp. 1453-1464
    • Milone, M.C.1    Fish, J.D.2    Carpenito, C.3
  • 18
    • 33845294816 scopus 로고    scopus 로고
    • CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells
    • Kowolik CM, Topp MS, Gonzalez S, et al: CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells. Cancer Res 66:10995-11004, 2006
    • (2006) Cancer Res , vol.66 , pp. 10995-11004
    • Kowolik, C.M.1    Topp, M.S.2    Gonzalez, S.3
  • 19
    • 79955517235 scopus 로고    scopus 로고
    • CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
    • Savoldo B, Ramos CA, Liu E, et al: CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest 121:1822-1826, 2011
    • (2011) J Clin Invest , vol.121 , pp. 1822-1826
    • Savoldo, B.1    Ramos, C.A.2    Liu, E.3
  • 20
    • 62549097817 scopus 로고    scopus 로고
    • Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
    • Carpenito C, Milone MC, Hassan R, et al: Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains. Proc Natl Acad Sci U S A 106:3360-3365, 2009
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3360-3365
    • Carpenito, C.1    Milone, M.C.2    Hassan, R.3
  • 21
    • 76349087378 scopus 로고    scopus 로고
    • Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3-kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication
    • Zhong XS, Matsushita M, Plotkin J, et al: Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3-kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication. Mol Ther 18:413-420, 2010
    • (2010) Mol Ther , vol.18 , pp. 413-420
    • Zhong, X.S.1    Matsushita, M.2    Plotkin, J.3
  • 22
    • 74949124101 scopus 로고    scopus 로고
    • 4-1BB and CD28 signaling plays a synergistic role in redirecting umbilical cord blood T cells against B-cell malignancies
    • Tammana S, Huang X, Wong M, et al: 4-1BB and CD28 signaling plays a synergistic role in redirecting umbilical cord blood T cells against B-cell malignancies. Hum Gene Ther 21:75-86, 2010
    • (2010) Hum Gene Ther , vol.21 , pp. 75-86
    • Tammana, S.1    Huang, X.2    Wong, M.3
  • 23
    • 34548485103 scopus 로고    scopus 로고
    • Optimizing adoptive polyclonal T cell immunotherapy of lymphomas, using a chimeric T cell receptor possessing CD28 and CD137 costimulatory domains
    • Wang J, Jensen M, Lin Y, et al: Optimizing adoptive polyclonal T cell immunotherapy of lymphomas, using a chimeric T cell receptor possessing CD28 and CD137 costimulatory domains. Hum Gene Ther 18:712-725, 2007
    • (2007) Hum Gene Ther , vol.18 , pp. 712-725
    • Wang, J.1    Jensen, M.2    Lin, Y.3
  • 24
    • 84860333968 scopus 로고    scopus 로고
    • CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: Pilot clinical trial results
    • Till BG, Jensen MC, Wang J, et al: CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: Pilot clinical trial results. Blood 119:3940-3950, 2012
    • (2012) Blood , vol.119 , pp. 3940-3950
    • Till, B.G.1    Jensen, M.C.2    Wang, J.3
  • 25
    • 77955510549 scopus 로고    scopus 로고
    • Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans
    • Jensen MC, Popplewell L, Cooper LJ, et al: Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans. Biol Blood Marrow Transplant 16:1245-1256, 2010
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 1245-1256
    • Jensen, M.C.1    Popplewell, L.2    Cooper, L.J.3
  • 26
    • 77950475517 scopus 로고    scopus 로고
    • Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
    • Morgan RA, Yang JC, Kitano M, et al: Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 18:843-851, 2010
    • (2010) Mol Ther , vol.18 , pp. 843-851
    • Morgan, R.A.1    Yang, J.C.2    Kitano, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.