MicroRNA-148b is down-regulated in non-small cell lung cancer and associated with poor survival

International Journal of Clinical and Experimental Pathology

Volumn 8, Issue 1, 2015, Pages 800-805

  Ge, Hui ^a   Li, Bin ^a   Hu, Wen Xia ^a   Li, Rui Juan ^a   Jin, Hao ^a   Gao, Meng Meng ^a   Ding, Cui Min ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

MicroRNAs; MiR 148b; NSCLC; Survival

Indexed keywords

MICRORNA; TUMOR MARKER;

ADULT; AGED; BIOSYNTHESIS; DOWN REGULATION; FEMALE; GENETICS; HUMAN; KAPLAN MEIER METHOD; LUNG TUMOR; MALE; MIDDLE AGED; MORTALITY; NON SMALL CELL LUNG CANCER; PATHOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; REAL TIME POLYMERASE CHAIN REACTION;

ADULT; AGED; BIOMARKERS, TUMOR; CARCINOMA, NON-SMALL-CELL LUNG; DOWN-REGULATION; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; MALE; MICRORNAS; MIDDLE AGED; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84923116167     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90.
2. Ling H, Fabbri M and Calin GA. MicroRNAs and other non-coding RNAs as targets for anticancer drug development. Nat Rev Drug Discov 2013; 12: 847-865.
3. Krol J, Loedige I and Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 2010; 11: 597-610.
4. Ebert MS and Sharp PA. Roles for microRNAs in conferring robustness to biological processes. Cell 2012; 149: 515-524.
5. Zhao G, Zhang JG, Liu Y, Qin Q, Wang B, Tian K, Liu L, Li X, Niu Y, Deng SC and Wang CY. miR-148b functions as a tumor suppressor in pancreatic cancer by targeting AMPKalpha1. Mol Cancer Ther 2013; 12: 83-93.
6. Song YX, Yue ZY, Wang ZN, Xu YY, Luo Y, Xu HM, Zhang X, Jiang L, Xing CZ and Zhang Y. Micro-RNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation. Mol Cancer 2011; 10: 1.
7. Ueda T, Volinia S, Okumura H, Shimizu M, Ta-ccioli C, Rossi S, Alder H, Liu CG, Oue N, Yasui W, Yoshida K, Sasaki H, Nomura S, Seto Y, Ka-minishi M, Calin GA and Croce CM. Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis. Lancet Oncol 2010; 11: 136-146.
8. Yu T, Wang XY, Gong RG, Li A, Yang S, Cao YT, Wen YM, Wang CM and Yi XZ. The expression profile of microRNAs in a model of 7,12-dime-thyl-benz[a]anthrance-induced oral carcinogenesis in Syrian hamster. J Exp Clin Cancer Res 2009; 28: 64.
9. Schetter AJ, Leung SY, Sohn JJ, Zanetti KA, Bowman ED, Yanaihara N, Yuen ST, Chan TL, Kwong DL, Au GK, Liu CG, Calin GA, Croce CM and Harris CC. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008; 299: 425-436.
10. Bloomston M, Frankel WL, Petrocca F, Volinia S, Alder H, Hagan JP, Liu CG, Bhatt D, Taccioli C and Croce CM. MicroRNA expression patterns to differentiate pancreatic adenocarcinoma fr-om normal pancreas and chronic pancreatitis. JAMA 2007; 297: 1901-1908.
11. Liu GL, Liu X, Lv XB, Wang XP, Fang XS and Sang Y. miR-148b functions as a tumor suppressor in non-small cell lung cancer by targeting carcinoembryonic antigen (CEA). Int J Clin Exp Med 2014; 7: 1990-1999.
12. Marshall E. Cancer research and the $90 billion metaphor. Science 2011; 331: 1540-1541.
13. Dekker A, Vinod S, Holloway L, Oberije C, Geo-rge A, Goozee G, Delaney GP, Lambin P and Thwaites D. Rapid learning in practice: A lung cancer survival decision support system in routine patient care data. Radiother Oncol 2014; [Epub ahead of print].
14. Huang Y, Shen XJ, Zou Q, Wang SP, Tang SM and Zhang GZ. Biological functions of microRNAs: a review. J Physiol Biochem 2011; 67: 129-139.
15. Perera RJ and Ray A. MicroRNAs in the search for understanding human diseases. BioDrugs 2007; 21: 97-104.
16. Calin GA and Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-866.
17. Kong W, Zhao JJ, He L and Cheng JQ. Strategies for profiling microRNA expression. J Cell Physiol 2009; 218: 22-25.
18. Deng S, Calin GA, Croce CM, Coukos G and Zhang L. Mechanisms of microRNA deregulation in human cancer. Cell Cycle 2008; 7: 2643-2646.
19. Cimino D, De Pitta C, Orso F, Zampini M, Casara S, Penna E, Quaglino E, Forni M, Damasco C, Pinatel E, Ponzone R, Romualdi C, Brisken C, De Bortoli M, Biglia N, Provero P, Lanfranchi G and Taverna D. miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1. FASEB J 2013; 27: 1223-1235.
20. Wu Y, Liu GL, Liu SH, Wang CX, Xu YL, Ying Y and Mao P. MicroRNA-148b enhances the radiosensitivity of non-Hodgkin's Lymphoma ce-lls by promoting radiation-induced apoptosis. J Radiat Res 2012; 53: 516-525.
21. Zhang Z, Zheng W and Hai J. MicroRNA-148b expression is decreased in hepatocellular carcinoma and associated with prognosis. Med Oncol 2014; 31: 984.