A prospective randomized phase II study comparing metronomic chemotherapy with chemotherapy (single agent cisplatin), in patients with metastatic, relapsed or inoperable squamous cell carcinoma of head and neck

Oral Oncology

Volumn 51, Issue 3, 2015, Pages 279-286

  Patil, Vijay Maruti ^a   Noronha, Vanita ^a   Joshi, Amit ^a   Muddu, Vamshi Krishna ^a   Dhumal, Sachin ^a   Bhosale, Bharatsingh ^a   Arya, Supreeta ^a   Juvekar, Shashikant ^a   Banavali, Shripad ^a   D'Cruz, Anil ^a   Bhattacharjee, Atanu ^b   Prabhash, Kumar ^a  

^a TATA MEMORIAL HOSPITAL   (India)

^b Malabar Cancer Centre ^*  (India)

Author keywords

Chemotherapy; Cisplatin; Head and neck cancer; Metronomic administration; Oral cancer; Palliative

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBOPLATIN; CELECOXIB; CETUXIMAB; CISPLATIN; CREATININE; ERLOTINIB; METHOTREXATE; PACLITAXEL; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE; CYCLOOXYGENASE 2 INHIBITOR; PYRAZOLE DERIVATIVE; SULFONAMIDE;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; ASPIRATION PNEUMONIA; CANCER COMBINATION CHEMOTHERAPY; CANCER PALLIATIVE THERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CEREBROVASCULAR ACCIDENT; CHEMOTHERAPY INDUCED ANEMIA; CHEMOTHERAPY INDUCED NAUSEA AND VOMITING; CLINICAL EFFECTIVENESS; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE CLEARANCE; DRUG EFFICACY; DRUG ERUPTION; DYSPHAGIA; ELECTROCORTICOGRAPHY; FATIGUE; FEMALE; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HYPOKALEMIA; HYPONATREMIA; INOPERABLE CANCER; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; METRONOMIC CHEMOTHERAPY; MUCOSA INFLAMMATION; MULTIMODALITY CANCER THERAPY; MULTIPLE CYCLE TREATMENT; NEUTROPENIA; OVERALL SURVIVAL; PARALLEL DESIGN; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTOPENIA; CARCINOMA, SQUAMOUS CELL; CLINICAL TRIAL; DISEASE FREE SURVIVAL; HEAD AND NECK NEOPLASMS; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; ORAL DRUG ADMINISTRATION; RISK FACTOR; TREATMENT OUTCOME;

ADMINISTRATION, INTRAVENOUS; ADMINISTRATION, ORAL; ADULT; AGED; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; CYCLOOXYGENASE 2 INHIBITORS; DISEASE-FREE SURVIVAL; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; METHOTREXATE; MIDDLE AGED; PROSPECTIVE STUDIES; PYRAZOLES; RISK FACTORS; SULFONAMIDES; TREATMENT OUTCOME;

EID: 84923106874     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2014.12.002     Document Type: Article

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