(Re)solving atherosclerosis

Science Translational Medicine

Volumn 7, Issue 275, 2015, Pages

  Soehnlein, Oliver ^a,b,c  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AC2-26 PEPTIDE; COLLAGEN TYPE 4; FORMYLPEPTIDE RECEPTOR; FORMYLPEPTIDE RECEPTOR 2; LIPOCORTIN 1; NANOPARTICLE; PROSTAGLANDIN SYNTHASE INHIBITOR; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ANTIBODY; UNCLASSIFIED DRUG; PEPTIDE;

ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL WALL; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG MECHANISM; DRUG TARGETING; INFLAMMATION; MACROPHAGE; NONHUMAN; OXIDATIVE STRESS; SHORT SURVEY; ANIMAL; COMPLICATION; HYPERCHOLESTEROLEMIA;

ANIMALS; ANNEXIN A1; ATHEROSCLEROSIS; HYPERCHOLESTEROLEMIA; NANOPARTICLES; PEPTIDES;

EID: 84923089497     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa5355     Document Type: Short Survey

References (10)

1. G. Fredman, N. Kamaly, S. Spolitu, J. Milton, D. Ghorpade, R. Chiasson, G. Kuriakose, M. Perretti, O. Farokzhad, I. Tabas, Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice. Sci. Transl. Med. 7, 275ra20 (2015).
2. C. Silvestre-Roig, M. P. de Winther, C. Weber, M. J. Daemen, E. Lutgens, O. Soehnlein, Atherosclerotic plaque destabilization: Mechanisms, models, and therapeutic strategies. Circ. Res. 114, 214-226 (2014).
3. P. Libby, I. Tabas, G. Fredman, E. A. Fisher, Inflammation and its resolution as determinants of acute coronary syndromes. Circ. Res. 114, 1867-1879 (2014).
4. A. Ortega-Gómez, M. Perretti, O. Soehnlein, Resolution of inflammation: An integrated view. EMBO Mol. Med. 5, 661-674 (2013).
5. S. Arur, U. E. Uche, K. Rezaul, M. Fong, V. Scranton, A. E. Cowan, W. Mohler, D. K. Han, Annexin I is an endogenous ligand that mediates apoptotic cell engulfment. Dev. Cell 4, 587-598 (2003).
6. Y. Li, L. Cai, H. Wang, P. Wu, W. Gu, Y. Chen, H. Hao, K. Tang, P. Yi, M. Liu, S. Miao, D. Ye, Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2. Oncogene 30, 3887-3899 (2011).
7. M. Drechsler, R. J. de Jong, J. Rossaint, J. Viola, G. Leoni, J. M. Wang, J. Grommes, R. Hinkel, C. Kupatt, C. Weber, Y. Doering, A. Zarbock, O. Soehnlein. Annexin A1 counteracts chemokine-induced arterial myeloid cell recruitment. Circ. Res. CIRCRESAHA.114.305825 (2014).
8. M. Spite, L. V. Norling, L. Summers, R. Yang, D. Cooper, N. A. Petasis, R. J. Flower, M. Perretti, C. N. Serhan, Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature 461, 1287-1291 (2009).
9. T. Gobbetti, S. M. Coldewey, J. Chen, S. McArthur, P. le Faouder, N. Cenac, R. J. Flower, C. Thiemermann, M. Perretti, Nonredundant protective properties of FPR2/ ALX in polymicrobial murine sepsis. Proc. Natl. Acad. Sci. U.S.A. 111, 18685-18690 (2014).
10. O. Soehnlein, S. Wantha, S. Simsekyilmaz, Y. Döring, R. T. Megens, S. F. Mause, M. Drechsler, R. Smeets, S. Weinandy, F. Schreiber, T. Gries, S. Jockenhoevel, M. Möller, S. Vijayan, M. A. van Zandvoort, B. Agerberth, C. T. Pham, R. L. Gallo, T. M. Hackeng, E. A. Liehn, A. Zernecke, D. Klee, C. Weber, Neutrophil-derived cathelicidin protects from neointimal hyperplasia. Sci. Transl. Med. 3, 103ra98 (2011).