Platelets from children are hyper-responsive to activation by thrombin receptor activator peptide and adenosine diphosphate compared to platelets from adults

British Journal of Haematology

Volumn 168, Issue 4, 2015, Pages 526-532

  Yip, Christina ^a,b   Linden, Matthew D ^c   Attard, Chantal ^b   Monagle, Paul ^a,b,d   Ignjatovic, Vera ^a,b  

^a MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

Agonists; Children; Flow cytometry; Monocyte platelet aggregates; Platelet activation

Indexed keywords

ADENOSINE DIPHOSPHATE; DUAL SPECIFICITY PHOSPHATASE 2; MEMBRANE PROTEIN; PADGEM PROTEIN; THROMBIN RECEPTOR ACTIVATOR PEPTIDE; UNCLASSIFIED DRUG; (4-BENZYLPIPERAZIN-1-YL)ACETIC ACID (3-ALLYL-2-HYDROXYBENZYLIDENE)HYDRAZINE; ARACHIDONIC ACID; HYDRAZONE DERIVATIVE; OLIGOPEPTIDE; PIPERAZINE DERIVATIVE; THROMBIN RECEPTOR;

ADULT; ARTICLE; CELL DIFFERENTIATION; CHILD; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FLOW CYTOMETRY; HUMAN; NORMAL HUMAN; PATHOGENESIS; PLATELET REACTIVITY; PROTEIN BINDING; PROTEIN EXPRESSION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; AGING; AGONISTS; BLOOD; CELL ADHESION; CYTOLOGY; DRUG EFFECTS; METABOLISM; MONOCYTE; THROMBOCYTE;

ADENOSINE DIPHOSPHATE; ADULT; AGING; ARACHIDONIC ACID; BLOOD PLATELETS; CELL ADHESION; CHILD; HUMANS; HYDRAZONES; MONOCYTES; OLIGOPEPTIDES; P-SELECTIN; PIPERAZINES; PLATELET ACTIVATION; RECEPTORS, THROMBIN;

EID: 84923072552     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13153     Document Type: Article

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