Can HIV-1 entry sites be deduced by comparing bulk endocytosis to functional readouts for viral fusion?

Journal of Virology

Volumn 89, Issue 5, 2015, Pages 2985-2985

  Marin, Mariana ^a   Melikyan, Gregory B ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPID;

ARTICLE; CD4+ T LYMPHOCYTE; CELL SURFACE; CELLULAR DISTRIBUTION; ENDOCYTOSIS; ENDOSOME; HUMAN IMMUNODEFICIENCY VIRUS 1; LYSOSOME; MICROSCOPY; NONHUMAN; VESICULOVIRUS; VIRAL FUSION; VIRAL PHENOMENA AND FUNCTIONS; VIRUS ENTRY; VIRUS IMMUNITY; VIRUS PARTICLE; CELL MEMBRANE; HUMAN; PHYSIOLOGY; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

CD4-POSITIVE T-LYMPHOCYTES; CELL MEMBRANE; ENDOCYTOSIS; HIV-1; HUMANS; VIRUS INTERNALIZATION;

EID: 84923044655     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03352-14     Document Type: Article

References (10)

1. Herold N, Anders-Osswein M, Glass B, Eckhardt M, Muller B, Krausslich HG. 2014. HIV-1 entry in SupT1-R5, CEM-ss, and primary CD4+ T-cells occurs at the plasma membrane and does not require endocytosis. J Virol 88:13956-13970. http://dx.doi.org/10.1128/JVI.01543-14.
2. de la Vega M, Marin M, Kondo N, Miyauchi K, Kim Y, Epand RF, Epand RM, Melikyan GB. 2011. Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion. Retrovirology 8:99. http://dx.doi.org/10.1186/1742-4690-8-99.
3. Miyauchi K, Kim Y, Latinovic O, Morozov V, Melikyan GB. 2009. HIV enters cells via endocytosis and dynamin-dependent fusion with endosomes. Cell 137:433-444. http://dx.doi.org/10.1016/j.cell.2009.02.046.
4. Schaeffer E, Soros VB, Greene WC. 2004. Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes. J Virol 78:1375-1383. http://dx.doi.org/10.1128/JVI.78.3.1375-1383.2004.
5. Marechal V, Clavel F, Heard JM, Schwartz O. 1998. Cytosolic Gag p24 as an index of productive entry of human immunodeficiency virus type 1. J Virol 72:2208-2212.
6. Huotari J, Helenius A. 2011. Endosome maturation. EMBO J 30:3481-3500. http://dx.doi.org/10.1038/emboj.2011.286.
7. Baravalle G, Schober D, Huber M, Bayer N, Murphy RF, Fuchs R. 2005. Transferrin recycling and dextran transport to lysosomes is differentially affected by bafilomycin, nocodazole, and low temperature. Cell Tissue Res 320:99-113. http://dx.doi.org/10.1007/s00441-004-1060-x.
8. +-ATPase regulation of endosomal acidification in K562 erythroleukemia cells. Analysis via inhibition of transferrin recycling by low temperatures. J Biol Chem 266:3469-3474.
9. Sullivan PC, Ferris AL, Storrie B. 1987. Effects of temperature, pH elevators, and energy production inhibitors on horseradish peroxidase transport through endocytic vesicles. J Cell Physiol 131:58-63. http://dx.doi.org/10.1002/jcp.1041310110.
10. Fomina AF, Deerinck TJ, Ellisman MH, Cahalan MD. 2003. Regulation of membrane trafficking and subcellular organization of endocytic compartments revealed with FM1-43 in resting and activated human T cells. Exp Cell Res 291:150-166. http://dx.doi.org/10.1016/S0014-4827(03)00372-0.