Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities

Infection and Immunity

Volumn 83, Issue 3, 2015, Pages 1030-1038

  Frandoloso, Rafael ^a,b   Martínez Martínez, Sonia ^b   Calmettes, Charles ^c   Fegan, Jamie ^d   Costa, Estela ^d   Curran, Dave ^d   Yu, Rong Hua ^d   Gutiérrez Martín, César B ^b   Rodríguez Ferri, Elías F ^b   Moraes, Trevor F ^c   Schryvers, Anthony B ^d  

^a UNIVERSITY OF PASSO FUNDO   (Brazil)

^b UNIVERSITY OF LEÓN   (Spain)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFERRIN BINDING PROTEIN B; BACTERIUM ANTIBODY; HAEMOPHILUS VACCINE; IMMUNOGLOBULIN M; IRON; RECOMBINANT PROTEIN; TRANSFERRIN;

ACTINOBACILLUS SUIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; EXPERIMENTAL PIG; HAEMOPHILUS INFECTION; HAEMOPHILUS PARASUIS; HAEMOPHILUS PARASUIS INFECTION; HELPER CELL; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; MENINGITIS; MOUSE; NONHUMAN; POLYARTHRITIS; POLYSEROSITIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; T LYMPHOCYTE; VACCINATION; ANIMAL; BIOSYNTHESIS; CELLULAR IMMUNITY; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HAEMOPHILUS INFECTIONS; HUMORAL IMMUNITY; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PIG;

ANIMALS; ANTIBODIES, BACTERIAL; B-LYMPHOCYTES; GENE EXPRESSION; HAEMOPHILUS INFECTIONS; HAEMOPHILUS PARASUIS; HAEMOPHILUS VACCINES; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNOGLOBULIN M; IRON; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT PROTEINS; SWINE; T-LYMPHOCYTES; TRANSFERRIN; TRANSFERRIN-BINDING PROTEIN B; VACCINATION;

EID: 84922971951     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.02572-14     Document Type: Article

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