The use of fondaparinux in pregnancy

British Journal of Haematology

Volumn 168, Issue 5, 2015, Pages 762-764

  Elsaigh, Esra ^a   Thachil, Jecko ^b   Nash, Michael J ^b   Tower, Clare ^c   Hay, Charles R M ^b   Bullough, Sian ^c   Byrd, Louise ^c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^c St Mary's Hospital   (United Kingdom)

Author keywords

Allergy; Fondaparinux; Heparin; Pregnancy

Indexed keywords

ANTIHISTAMINIC AGENT; DALTEPARIN; ENOXAPARIN; FONDAPARINUX; NADROPARIN; STEROID; TINZAPARIN; ANTICOAGULANT AGENT; POLYSACCHARIDE;

ALLERGY; ANTICOAGULATION; ARTICLE; BLOOD PLACENTA BARRIER; DEEP VEIN THROMBOSIS; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FETAL WELL BEING; FETUS DISEASE; FETUS MOVEMENT; FIRST TRIMESTER PREGNANCY; HEALTH CARE PLANNING; HEALTH IMPACT ASSESSMENT; HIGH RISK PATIENT; HUMAN; LOW DRUG DOSE; MATERNAL WELFARE; OPERATION DURATION; PREGNANCY; PREGNANCY TERMINATION; PREGNANT WOMAN; RECOMMENDED DRUG DOSE; RECURRENT DISEASE; SECOND TRIMESTER PREGNANCY; SKIN DEFECT; SPONTANEOUS ABORTION; THIRD TRIMESTER PREGNANCY; TREATMENT FAILURE; UMBILICAL CORD BLOOD; VENOUS THROMBOEMBOLISM; PREGNANCY COMPLICATIONS, HEMATOLOGIC;

ANTICOAGULANTS; FEMALE; HUMANS; POLYSACCHARIDES; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; VENOUS THROMBOEMBOLISM;

EID: 84922950419     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13147     Document Type: Article

References (10)

1. Bank, I., Libourel, E., Middeldorp, S., Van Der Meer, J. & Büller, H. (2003) High rate of skin complications due to low-molecular-weight heparins in pregnant women. Journal of Thrombosis and Haemostasis, 1, 859-861.
2. Ciurzynski, M., Jankowski, K., Pietrzak, B., Mazanowska, N., Rzewuska, E. & Pruszczyk, P. (2011) Use of fondaparinux in a pregnant woman with pulmonary embolism and heparin-induced thrombocytopeniaMedical Science Monitor, 17, Cs56-Cs59.
3. Dempfle, C. (2004) Minor transplacental passage of fondaparinux in vivo. New England Journal of Medicine, 350, 1914-1915.
4. Efird, L.E. & Kockler, D.R. (2006) Fondaparinux for thromboembolic treatment and prophylaxis of heparin-induced thrombocytopenia. Annals of Pharmacotherapy, 40, 1383-1387.
5. Knol, H., Schultinge, L., Erwich, J. & Meijer, K. (2010) Fondaparinux as an alternative anticoagulant therapy during pregnancy. Journal of Thrombosis and Haemostasis, 8, 1876-1879.
6. Mazzolai, L., Hohlfeld, P., Spertini, F., Hayoz, D., Schapira, M. & Duchosal, M. (2006) Fondaparinux is a safe alternative in case of heparin intolerance during pregnancy. Blood, 108, 1569-1570.
7. RCOG (1995). Report of the RCOG Working Party on Prophylaxis Against Thromboembolism in Gynaecology and Obstetrics. Royal College of Obstetricians and Gynaecologists, London, UK.
8. Rubin, N. & Rubin, J. (2003) Treatment of heparin induced thrombocytopenia with thrombosis (HITT) in pregnancy with fondaparinux [abstract]. Blood, 102, 4190.
9. Schindewolf, M., Gobst, C., Kroll, H., Recke, A., Louwen, F., Wolter, M., Kaufmann, R., Boehncke, W.-H., Lindhoff-Last, E. & Ludwig, R.J. (2013) High incidence of heparin-induced allergic delayed-type hypersensitivity reactions in pregnancy. The Journal of Allergy and Clinical Immunology, 132, 131-139.
10. Wijesiriwardana, A., Lees, D. & Lush, C. (2006) Fondaparinux as anticoagulant in a pregnant woman with heparin allergy. Blood Coagulation & Fibrinolysis, 17, 147-149.