Interstitial lung disease-associated with amyopathic dermatomyositis and anti-MDA5 autoantibodies;Pneumopathie infiltrante diffuse associée à une dermatomyosite amyopathique avec auto-anticorps anti-MDA5

Revue des Maladies Respiratoires

Volumn 31, Issue 9, 2014, Pages 849-853

  Gerfaud Valentin, M ^a   Ahmad, K ^a   Piegay, F ^a   Fabien, N ^b   Raphanel, B ^c   Cordier, J F ^a   Cottin, V ^a  

^a UNIVERSITÉ LYON 1   (France)

^b CENTRE HOSPITALIER LYON SUD   (France)

^c Cabinet de Pneumologie   (France)

Author keywords

Anti MDA5 autoantibodies; Anti synthetase autoantibodies; Dermatomyositis; Interstitial lung disease; Organising pneumonia

Indexed keywords

ANTINUCLEAR ANTIBODY; AUTOANTIBODY; CARBON MONOXIDE; CORTICOSTEROID; CREATINE KINASE; FERRITIN; MDA5 AUTOANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; UNCLASSIFIED DRUG; DEAD BOX PROTEIN; IFIH1 PROTEIN, HUMAN;

ADULT; ARTHRITIS; ARTICLE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; COUGHING; CREATINE KINASE BLOOD LEVEL; DERMATOMYOSITIS; DISEASE ASSOCIATION; DYSPNEA; EARLY DIAGNOSIS; ELECTROMYOGRAPHY; FEMALE; FERRITIN BLOOD LEVEL; HUMAN; HYPOXEMIA; INTERSTITIAL LUNG DISEASE; LUNG AUSCULTATION; LUNG DIFFUSION CAPACITY; LUNG FUNCTION TEST; LUNG LAVAGE; MIDDLE AGED; NEUTROPHIL; ORGANIZING PNEUMONIA; PAPULE; RASH; SYSTEMIC THERAPY; TREATMENT OUTCOME; BLOOD; COMPLICATION; IMMUNOLOGY; LUNG DISEASES, INTERSTITIAL; THORAX RADIOGRAPHY;

AUTOANTIBODIES; DEAD-BOX RNA HELICASES; DERMATOMYOSITIS; ELECTROMYOGRAPHY; FEMALE; HUMANS; LUNG DISEASES, INTERSTITIAL; MIDDLE AGED; RADIOGRAPHY, THORACIC;

EID: 84922935871     PISSN: 07618425     EISSN: 17762588     Source Type: Journal    
DOI: 10.1016/j.rmr.2014.02.010     Document Type: Article

References (15)

1. Marie I, Hatron PY, Dominique S, et al. Short-term and long- term outcomes of interstitial lung disease in polymyositis and dermatomyositis: a series of 107 patients. Arthritis Rheum 2011; 63: 3439-47.
2. Cottin V, Thivolet-Béjui F, Reynaud-Gaubert M, et al. Interstitial lung disease in amyopathic dermatomyositis, dermatomyositis and polymyositis. Eur Respir J 2003; 22: 245-50.
3. Vij R, Strek ME. Diagnosis and treatment of connective tissue disease-associated interstitial lung disease. Chest 2013; 143: 814-24.
4. Hervier B, Devilliers H, Stanciu R, et al. Hierarchical cluster and survival analyses of antisynthetase syndrome: phenotype and outcome are correlated with anti-tRNA synthetase antibody specificity. Autoimmun Rev 2012; 12: 210-7.
5. Euwer RL, Sontheimer RD. Amyopathic dermatomyositis (der- matomyositis sine myositis). Presentation of six new cases and review of the literature. J Am Acad Dermatol 1991; 24: 959-66.
6. Suda T, Fujisawa T, Enomoto N, et al. Interstitial lung diseases associated with amyopathic dermatomyositis. Eur Respir J 2006; 28: 1005-12.
7. Mukae H, Ishimoto H, Sakamoto N, et al. Clinical differences between interstitial lung disease associated with clinically amyopathic dermatomyositis and classic dermatomyositis. Chest 2009; 136: 1341-7.
8. Gono T, Kawaguchi Y, Satoh T, et al. Clinical manifestation and prognostic factor in anti-melanoma differentiation- associated gene 5 antibody-associated interstitial lung disease as a complication of dermatomyositis. Rheumatology (Oxford) 2010; 49: 1713-9.
9. Tanizawa K, Handa T, Nakashima R, et al. HRCT features of interstitial lung disease in dermatomyositis with anti-CADM- 140 antibody. Respir Med 2011; 105: 1380-7.
10. Gono T, Sato S, Kawaguchi Y, et al. Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis. Rheumatology (Oxford) 2012; 51: 1563-70.
11. Hall JC, Casciola-Rosen L, Samedy LA, et al. Anti-MDA5- associated dermatomyositis: expanding the clinical spectrum. Arthritis Care Res 2013; 65: 1307-15.
12. Cottin V. Interstitial lung disease: are we missing formes frustes of connective tissue disease? Eur Respir J 2006; 28: 893-6.
13. Chen Z, Cao M, Plana MN, et al. Utility of anti-melanoma differentiation-associated gene 5 antibody measurement in identifying patients with dermatomyositis and a high risk for developing rapidly progressive interstitial lung disease: a review of the literature and a meta-analysis. Arthritis Care Res 2013; 65: 1316-24.
14. Uzunhan Y, Nunes H, Leroux G, et al. Dermato-pulmonary syn- drome associated with MDA-5 antibodies: report of the first French series. 2013 ERS congress; poster 1554.
15. Marie I, Mouthon L. Therapy of polymyositis and dermatomyo- sitis. Autoimmun Rev 2011; 11: 6-13.