De novo donor-specific HLA antibodies are associated with early and high-grade bronchiolitis obliterans syndrome and death after lung transplantation

Journal of Heart and Lung Transplantation

Volumn 33, Issue 12, 2014, Pages 1288-1294

  Morrell, Matthew R ^a   Pilewski, Joseph M ^a   Gries, Cynthia J ^a   Pipeling, Matthew R ^a   Crespo, Maria M ^a   Ensor, Christopher R ^b   Yousem, Samuel A ^a   D'Cunha, Jonathan ^a   Shigemura, Norihisa ^a   Bermudez, Christian A ^a   McDyer, John F ^a   Zeevi, Adriana ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

bronchiolitis obliterans syndrome; death; donor specific antibody; human leukocyte antigen; lung transplant

Indexed keywords

ALEMTUZUMAB; AZATHIOPRINE; CYCLOSPORIN; DE NOVO DONOR SPECIFIC HLA ANTIBODY; HLA ANTIBODY; MYCOPHENOLIC ACID; PANEL REACTIVE ANTIBODY; PREDNISONE; UNCLASSIFIED DRUG; VALGANCICLOVIR; VORICONAZOLE; ANTIIDIOTYPIC ANTIBODY; BIOLOGICAL MARKER; HLA ANTIGEN;

ACUTE GRAFT REJECTION; ADULT; ANTIBODY RESPONSE; ARTICLE; ASSAY; BRONCHIOLITIS OBLITERANS; BRONCHOSCOPY; CAUSE OF DEATH; COHORT ANALYSIS; COMPARATIVE STUDY; CROSS-SECTIONAL STUDY; CYTOMEGALOVIRUS INFECTION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; FORCED EXPIRATORY VOLUME; FUNGAL PROPHYLAXIS; GRAFT FAILURE; HUMAN; LUNG FUNCTION; LUNG TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PATIENT CARE; PRIORITY JOURNAL; PROPHYLAXIS; PROSPECTIVE STUDY; SINGLE ANTIGEN BEAD ASSAY; STUDY DESIGN; AGED; DONOR; IMMUNOLOGY; LUNG; METABOLISM; MIDDLE AGED; PATHOLOGY; POSTOPERATIVE PERIOD; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; RISK FACTOR; SURVIVAL RATE;

ADULT; AGED; ANTIBODIES, ANTI-IDIOTYPIC; BIOMARKERS; BRONCHIOLITIS OBLITERANS; BRONCHOSCOPY; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; HLA ANTIGENS; HUMANS; LUNG; LUNG TRANSPLANTATION; MALE; MIDDLE AGED; POSTOPERATIVE PERIOD; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE; TISSUE DONORS;

EID: 84922908736     PISSN: 10532498     EISSN: 15573117     Source Type: Journal    
DOI: 10.1016/j.healun.2014.07.018     Document Type: Article

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