Long-term effects of contralesional rTMS in severe stroke: Safety, cortical excitability, and relationship with transcallosal motor fibers

NeuroRehabilitation

Volumn 36, Issue 1, 2015, Pages 51-59

  Demirtas Tatlidede, Asli ^a,b   Alonso Alonso, Miguel ^a   Shetty, Ravi P ^c   Ronen, Itamar ^c,d   Pascual Leone, Alvaro ^a   Fregni, Felipe ^a,e,f  

^a HARVARD MEDICAL SCHOOL   (United States)

^b ISTANBUL UNIVERSITY   (Turkey)

^c BOSTON UNIVERSITY   (United States)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e and Red Sox Foundation and Massachusetts General Hospital Home Base Program   (United States)

^f Department of Neurology Istanbul University Medical Faculty ^*  (United States)

Author keywords

cerebrovascular disease; cortical excitability; diffusion tensor imaging (DTI); neurorehabilitation; repetitive transcranial magnetic stimulation (rTMS); Severe stroke

Indexed keywords

PARACETAMOL;

ADULT; AGED; APPLICATION SITE DISCOMFORT; ARTICLE; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; DIFFUSION TENSOR IMAGING; DISEASE SEVERITY; EXCITABILITY; FEMALE; FOLLOW UP; FRACTIONAL ANISOTROPY; GRIP STRENGTH; HEADACHE; HUMAN; LONG TERM CARE; MALE; MIDDLE AGED; MOTOR CORTEX; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; PATIENT COMPLIANCE; PATIENT SAFETY; PRIMARY MOTOR CORTEX; REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION; STROKE PATIENT; THERAPY EFFECT; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME; TREATMENT RESPONSE; ADVERSE EFFECTS; BRAIN CORTEX; CORPUS CALLOSUM; HEMISPHERIC DOMINANCE; MOTONEURON; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; STROKE; TIME;

ADULT; AGED; CEREBRAL CORTEX; CORPUS CALLOSUM; DIFFUSION TENSOR IMAGING; FEMALE; FOLLOW-UP STUDIES; FUNCTIONAL LATERALITY; HUMANS; MALE; MIDDLE AGED; MOTOR CORTEX; MOTOR NEURONS; STROKE; TIME FACTORS; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME;

EID: 84922876412     PISSN: 10538135     EISSN: 18786448     Source Type: Journal    
DOI: 10.3233/NRE-141191     Document Type: Article

References (32)

1. Bütefisch, C. M., Wessling, M., Netz, J., Seitz, R. J., & Hömberg, V. (2008). Relationship between interhemispheric inhibition and motor cortex excitability in subacute stroke patients. Neurorehabilitation and Neural Repair, 22, 4-21
2. Caramia, M. D., Palmieri, M. G., Giacomini, P., Iani, C., Dally, L., & Silvestrini, M. (2000). Ipsilateral activation of the unaffected motor cortex in patients with hemiparetic stroke. Clinical Neurophysiology, 111, 1990-1996
3. Conforto, A. B., Anjos, S. M., Saposnik, G., Mello, E. A., Nagaya, E. M., Santos, W., Jr., Ferreiro, K. N., Melo, E. S., Reis, F. I., Scaff, M., & Cohen, L. G. (2012). Transcranial magnetic stimulation in mild to severe hemiparesis early after stroke: A proof of principle and novel approach to improve motor function. Journal of Neurology, 259, 1399-1405
4. Di Lazzaro, V., Pilato, F., Dileone, M., Ranieri, F., Ricci, V., Profice, P., Bria, P., Tonali, P. A.,&Ziemann, U. (2006). GABAA receptor subtype specific enhancement of inhibition in human motor cortex. Journal of Physiology, 575, 721-726
5. Fauth, C., Meyer, B. U., Prosiegel, M., Zihl, J., & Conrad, B. (1992). Seizure induction and magnetic brain stimulation after stroke. Lancet, 339, 362.
6. Ferbert, A., Priori, A., Rothwell, J. C., Day, B. L., Colebatch, J. G., & Marsden, C. D. (1992). Interhemispheric inhibition of the human motor cortex. Journal of Physiology, 453, 525-546
7. Fisher,C.M. (1992). Concerning the mechanism of recovery in stroke hemiplegia. Canadian Journal of Neurological Sciences, 19, 57-63
8. Fling, B. W., Benson, B. L., & Seidler, R. D. (2013). Transcallosal sensorimotor fiber tract structure-function relationships. Human Brain Mapping, 34, 384-395
9. Fregni, F., Boggio, P. S., Valle, A. C., Rocha, R. R., Duarte, J., Ferreira, M. J., Wagner, T., Fecteau, S., Rigonatti, S. P., Riberto, M., Freedman, S. D., & Pascual-Leone, A. (2006). A sham-controlled trial of a 5-day course of repetitive transcranial magnetic stimulation of the unaffected hemisphere in stroke patients. Stroke, 37, 2115-2122
10. Grefkes, C., Nowak, D. A., Eickhoff, S. B., Dafotakis, M., Küst, J., Karbe, H., & Fink, G. R. (2008). Cortical connectivity after subcortical stroke assessed with functional magnetic resonance imaging. Annals of Neurology, 63, 236-246
11. Groppa, S., Oliviero, A., Eisen, A., Quartarone, A., Cohen, L. G., Mall, V., Kaelin-Lang, A., Mima, T., Rossi, S., Thickbroom, G. W., Rossini, P. M., Ziemann, U., Valls-Solé, J., & Siebner, H. R. (2012).Apractical guide to diagnostic transcranial magnetic stimulation: Report of an IFCN committee. Clinical Neurophysiology, 123, 858-882
12. Hess, G., & Donoghue, J. P. (1994). Long-term potentiation of horizontal connections provides a mechanism to reorganize cortical motor maps. Journal of Neurophysiology, 71, 2543-2547
13. Hömberg, V., & Netz, J. (1989). Generalized seizures induced by transcranial magnetic stimulation of motor cortex. Lancet, 2, 1223.
14. Huynh,W., Vucic, S., Krishnan, A. V., Lin, C. S., Hornberger, M., & Kiernan, M. C. (2013). Longitudinal Plasticity Across the Neural Axis in Acute Stroke. Neurorehabilitation and Neural Repair, 27, 219-229
15. Jacobs, K. M.,&Donoghue, J. P. (1991). Reshaping the cortical motor map by unmasking latent intracortical connections. Science, 251, 944-947
16. Jang, S. H. (2009). A review of the ipsilateral motor pathway as a recovery mechanism in patients with stroke. NeuroRehabilitation, 24, 315-320
17. Jang, S. H. (2010). Prediction of motor outcome for hemiparetic stroke patients using diffusion tensor imaging: A review. NeuroRehabilitation, 27, 367-372
18. Jones, D. K., Simmons, A., Williams, S. C., & Horsfield, M. A. (1999). Non-invasive assessment of axonal fiber connectivity in the human brain via diffusion tensor MRI. Magnetic Resonance in Medicine, 42, 37-41
19. Liepert, J., Classen, J., Cohen, L. G., & Hallett, M. (1998). Taskdependent changes of intracortical inhibition. Experimental Brain Research, 118, 421-426
20. Lindenberg, R., Renga, V., Zhu, L. L., Betzler, F., Alsop, D., & Schlaug, G. (2010). Structural integrity of corticospinal motor fibers predicts motor impairment in chronic stroke. Neurology, 74, 280-287
21. Málly, J., & Dinya, E. (2008). Recovery of motor disability and spasticity in post-stroke after repetitive transcranial magnetic stimulation (rTMS). Brain Research Bulletin, 76, 388-395
22. Mansur, C. G., Fregni, F., Boggio, P. S., Riberto, M., Gallucci-Neto, J., Santos, C. M.,Wagner, T., Rigonatti, S. P.,Marcolin, M. A., & Pascual-Leone, A. (2005). A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients. Neurology, 64, 1802-1804
23. Murase, N., Duque, J., Mazzocchio, R., & Cohen, L.G. (2004). Influence of interhemispheric interactions on motor function in chronic stroke. Annals of Neurology, 55, 400-409
24. Sterr, A., Shen, S., Szameitat, A. J., & Herron, K. A. (2010). The role of corticospinal tract damage in chronic motor recovery and neurorehabilitation: A pilot study. Neurorehabilitation & Neural Repair, 24, 413-419
25. Stinear, C. M., Barber, P. A., Smale, P. R., Coxon, J. P., Fleming, M. K., & Byblow, W. D. (2007). Functional potential in chronic stroke patients depends on corticospinal tract integrity. Brain, 130, 170-180
26. Takeuchi, N., Chuma, T., Matsuo, Y., Watanabe, I., & Ikoma, K. (2005). Repetitive transcranial magnetic stimulation of contralesional primary motor cortex improves hand function after stroke. Stroke, 36, 2681-2686
27. Ugawa, Y., Hanajima, R., & Kanazawa, I. (1993). Interhemispheric facilitation of the hand area of the human motor cortex. Neuroscience Letters, 160, 153-155
28. Wahl, M., Lauterbach-Soon, B., Hattingen, E., Jung, P., Singer, O., Volz, S., Klein, J. C., Steinmetz, H., & Ziemann, U. (2007). Humanmotor corpus callosum:Topography, somatotopy, and link between microstructure and function. Journal of Neuroscience, 27, 12132-12138
29. Wang, L. E., Tittgemeyer, M., Imperati, D., Diekhoff, S., Ameli, M., Fink, G. R., & Grefkes, C. (2012). Degeneration of corpus callosum and recovery of motor function after stroke: A multimodal magnetic resonance imaging study. Human Brain Mapping, 33, 2941-2956
30. Werhahn, K. J., Mortensen, J., Kaelin-Lang, A., Boroojerdi, B., & Cohen, L. G. (2002). Cortical excitability changes induced by deafferentation of the contralateral hemisphere. Brain, 125, 1402-1413.
31. Yousry, T., Schmid, U., Alkadhi, H., Schmidt, D., Peraud, A., Buettner, A., & Winkler, P. (1997). Localization of the motor hand area to a knob on the precentral gyrus. Brain, 120, 141-157
32. Ziemann, U., Rothwell, J. C., & Ridding, M. C. (1996). Interaction between intracortical inhibition and facilitation in human motor cortex. Journal of Physiology, 496, 873-881