Site-specific proteolytic degradation of IgG monoclonal antibodies expressed in tobacco plants

Plant Biotechnology Journal

Volumn 13, Issue 2, 2015, Pages 235-245

  Hehle, Verena K ^a   Lombardi, Raffaele ^b   van Dolleweerd, Craig J ^a   Paul, Mathew J ^a   Di Micco, Patrizio ^c   Morea, Veronica ^c   Benvenuto, Eugenio ^b   Donini, Marcello ^b   Ma, Julian K C ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b ENEA C R CASACCIA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Molecular farming; Monoclonal antibodies; N terminal sequencing; Proteolysis

Indexed keywords

NICOTIANA OBTUSIFOLIA;

IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY;

AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; GLYCOSYLATION; IMMUNOBLOTTING; METABOLISM; MOLECULAR GENETICS; PROTEIN DEGRADATION; SEQUENCE ANALYSIS; TOBACCO; TRANSGENIC PLANT;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; GLYCOSYLATION; IMMUNOBLOTTING; IMMUNOGLOBULIN G; MOLECULAR SEQUENCE DATA; PLANTS, GENETICALLY MODIFIED; PROTEOLYSIS; SEQUENCE ANALYSIS, PROTEIN; TOBACCO;

EID: 84922753792     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/pbi.12266     Document Type: Article

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