메뉴 건너뛰기




Volumn 457, Issue 3, 2015, Pages 461-466

Inhibition of Mer and Axl receptor tyrosine kinases leads to increased apoptosis and improved chemosensitivity in human neuroblastoma

Author keywords

Axl; Chemosensitivity; Mer; Receptor tyrosine kinase; Targeted therapy

Indexed keywords

AXL RECEPTOR TYROSINE KINASE; CISPLATIN; FAK PROTEIN; GROWTH ARREST SPECIFIC PROTEIN 6; MER RECEPTOR TYROSINE KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; VINCRISTINE; GROWTH ARREST-SPECIFIC PROTEIN 6; LIGAND; MERTK PROTEIN, HUMAN; ONCOPROTEIN; SIGNAL PEPTIDE;

EID: 84922715769     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.01.017     Document Type: Article
Times cited : (24)

References (23)
  • 1
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: Biological insights into a clinical enigma
    • G.M. Brodeur, Neuroblastoma: biological insights into a clinical enigma, Nat. Rev. Cancer 3 (2003) 203-216.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 4
    • 0021261878 scopus 로고
    • Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
    • G.M. Brodeur, R.C. Seeger, M. Schwab, H.E. Varmus, J.M. Bishop, Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage, Science 224 (1984) 1121-1124.
    • (1984) Science , vol.224 , pp. 1121-1124
    • Brodeur, G.M.1    Seeger, R.C.2    Schwab, M.3    Varmus, H.E.4    Bishop, J.M.5
  • 7
    • 84927145873 scopus 로고    scopus 로고
    • Targeting receptor tyrosine kinases and their downstream signaling with cellpenetrating peptides in human pulmonary artery smooth muscle and endothelial cells
    • J. Yu, C. Rupasinghe, J.L. Wilson, L. Taylor, N. Rahimi, D. Mierke, P. Polgar, Targeting receptor tyrosine kinases and their downstream signaling with cellpenetrating peptides in human pulmonary artery smooth muscle and endothelial cells, Chem. Biol. Drug Des. (2014), http://dx.doi.org/10.1111/cbdd.12446.
    • (2014) Chem. Biol. Drug Des.
    • Yu, J.1    Rupasinghe, C.2    Wilson, J.L.3    Taylor, L.4    Rahimi, N.5    Mierke, D.6    Polgar, P.7
  • 8
    • 84907443858 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the receptor tyrosine kinases: Promising tools for targeted cancer therapies
    • M. Hojjat-Farsangi, Small-molecule inhibitors of the receptor tyrosine kinases: promising tools for targeted cancer therapies, Int. J. Mol. Sci. 15 (2014) 13768-13801.
    • (2014) Int. J. Mol. Sci. , vol.15 , pp. 13768-13801
    • Hojjat-Farsangi, M.1
  • 9
    • 84890794931 scopus 로고    scopus 로고
    • TAM receptor tyrosine kinases: Expression, disease and oncogenesis in the central nervous system
    • A.M. Pierce, A.K. Keating, TAM receptor tyrosine kinases: expression, disease and oncogenesis in the central nervous system, Brain Res. 1542 (2014) 206-220.
    • (2014) Brain Res. , vol.1542 , pp. 206-220
    • Pierce, A.M.1    Keating, A.K.2
  • 11
  • 17
    • 77957092501 scopus 로고    scopus 로고
    • Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors
    • R.M. Linger, A.K. Keating, H.S. Earp, D.K. Graham, Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors, Expert Opin. Ther. Targets 14 (2010) 1073-1090.
    • (2010) Expert Opin. Ther. Targets , vol.14 , pp. 1073-1090
    • Linger, R.M.1    Keating, A.K.2    Earp, H.S.3    Graham, D.K.4
  • 19
    • 85047698138 scopus 로고    scopus 로고
    • Akt is required for Axl-Gas6 signaling to protect cells from E1A-mediated apoptosis
    • W.P. Lee, Y. Wen, B. Varnum, M.C. Hung, Akt is required for Axl-Gas6 signaling to protect cells from E1A-mediated apoptosis, Oncogene 21 (2002) 329-336.
    • (2002) Oncogene , vol.21 , pp. 329-336
    • Lee, W.P.1    Wen, Y.2    Varnum, B.3    Hung, M.C.4
  • 20
    • 0030981120 scopus 로고    scopus 로고
    • Identification of Gas6 as a ligand for Mer, a neural cell adhesion molecule related receptor tyrosine kinase implicated in cellular transformation
    • J. Chen, K. Carey, P.J. Godowski, Identification of Gas6 as a ligand for Mer, a neural cell adhesion molecule related receptor tyrosine kinase implicated in cellular transformation, Oncogene 14 (1997) 2033-2039.
    • (1997) Oncogene , vol.14 , pp. 2033-2039
    • Chen, J.1    Carey, K.2    Godowski, P.J.3
  • 21
    • 70349705633 scopus 로고    scopus 로고
    • Axl as a potential therapeutic target in cancer: Role of Axl in tumor growth, metastasis and angiogenesis
    • Y. Li, X. Ye, C. Tan, J.A. Hongo, J. Zha, J. Liu, D. Kallop, M.J. Ludlam, L. Pei, Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis, Oncogene 28 (2009) 3442-3455.
    • (2009) Oncogene , vol.28 , pp. 3442-3455
    • Li, Y.1    Ye, X.2    Tan, C.3    Hongo, J.A.4    Zha, J.5    Liu, J.6    Kallop, D.7    Ludlam, M.J.8    Pei, L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.