메뉴 건너뛰기




Volumn 34, Issue 2, 2015, Pages 271-276

The decline of venture capital investment in early-stage life sciences poses a challenge to continued innovation

Author keywords

[No Author keywords available]

Indexed keywords

NEW DRUG;

EID: 84922714689     PISSN: 02782715     EISSN: 15445208     Source Type: Journal    
DOI: 10.1377/hlthaff.2014.1051     Document Type: Article
Times cited : (41)

References (16)
  • 1
    • 84927749335 scopus 로고    scopus 로고
    • Cost to develop and win marketing approval for a new drug is $2.6 billion [Internet]
    • Boston (MA): Tufts University; 2014 Nov 18, cited, Dec 17, Available from
    • Tufts Center for the Study of Drug Development. Cost to develop and win marketing approval for a new drug is $2.6 billion [Internet]. Boston (MA): Tufts University; 2014 Nov 18 [cited 2014 Dec 17]. Available from: http://csdd.tufts.edu/news/complete_story/pr_tufts_csdd_2014_cost_study
    • (2014)
  • 2
    • 77149155968 scopus 로고    scopus 로고
    • Trends in risks associated with new drug development: success rates for investigational drugs
    • DiMasi JA, Feldman L, Seckler A, Wilson A. Trends in risks associated with new drug development: success rates for investigational drugs. Clin Pharmacol Ther. 2010;87(3):272-7.
    • (2010) Clin Pharmacol Ther. , vol.87 , Issue.3 , pp. 272-277
    • DiMasi, J.A.1    Feldman, L.2    Seckler, A.3    Wilson, A.4
  • 3
    • 84922707022 scopus 로고    scopus 로고
    • Patient capital 3.0: confronting the crisis and achieving the promise of venture-backed medical innovation [Internet]
    • Washington (DC): NCVA, cited 2014 Dec 17, Available from
    • National Venture Capital Association. Patient capital 3.0: confronting the crisis and achieving the promise of venture-backed medical innovation [Internet]. Washington (DC): NCVA; 2013 [cited 2014 Dec 17]. Available from: http://www.nvca.org/index.php?option=com_content&view=article&id=268 &Itemid=103
    • (2013)
  • 4
    • 84922697228 scopus 로고    scopus 로고
    • Putting a price on biotechnology. Bioentrepreneur [serial on the Internet]
    • Sep [cited 2015 Jan 5], Available from
    • Stewart JJ, Allison PN, Johnson RS. Putting a price on biotechnology. Bioentrepreneur [serial on the Internet]. 2001 Sep [cited 2015 Jan 5]. Available from: http://www.nature.com/bioent/2003/030101/full/nbt0901-813.html
    • (2001)
    • Stewart, J.J.1    Allison, P.N.2    Johnson, R.S.3
  • 5
    • 84922732295 scopus 로고    scopus 로고
    • Net present value approaches for drug delivery. Springerplus [serial on the Internet]
    • Apr 1 [cited 2015 Jan 5]. Available from
    • Svennebring AM, Wikberg JES. Net present value approaches for drug delivery. Springerplus [serial on the Internet]. 2013 Apr 1 [cited 2015 Jan 5]. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622797/
    • (2013)
    • Svennebring, A.M.1    Wikberg, J.E.S.2
  • 6
    • 84922756499 scopus 로고    scopus 로고
    • Year-to-date venture capital dollars invested eclipses total dollars invested in all of 2013 [Internet]
    • Washington (DC): NVCA, Oct 17 [cited 2014 Dec 17], Available from
    • National Venture Capital Association. Year-to-date venture capital dollars invested eclipses total dollars invested in all of 2013 [Internet]. Washington (DC): NVCA; 2014 Oct 17 [cited 2014 Dec 17]. Available from: https://www.pwcmoneytree.com/NewsFeed
    • (2014)
  • 7
    • 85060026468 scopus 로고    scopus 로고
    • Trends in healthcare investments and exits 2014 [Internet]
    • Santa Clara (CA): Silicon Valley Bank, cited 2014 Dec 17, Available from
    • Norris J. Trends in healthcare investments and exits 2014 [Internet]. Santa Clara (CA): Silicon Valley Bank; 2014 [cited 2014 Dec 17]. Available from: http://www.svb.com/healthcare-report/
    • (2014)
    • Norris, J.1
  • 8
    • 84922718700 scopus 로고    scopus 로고
    • Acceptance and filing reviews for premarket approval applications (PMAs): guidance for industry and Food and Drug Administration staff [Internet]
    • Silver Spring (MD): FDA; 2012 Dec 31 [cited 2014 Dec 17]. Available from
    • Food and Drug Administration. Acceptance and filing reviews for premarket approval applications (PMAs): guidance for industry and Food and Drug Administration staff [Internet]. Silver Spring (MD): FDA; 2012 Dec 31 [cited 2014 Dec 17]. Available from: http://www.fda.gov/downloads/medicaldevices/deviceregulationandguidance/guidance documents/ucm313368.pdf
  • 9
    • 84922701491 scopus 로고    scopus 로고
    • The FDA's drug review process: ensuring drugs are safe and effective [Internet]
    • Silver Spring (MD): FDA, cited, Dec 17, Available from
    • Food and Drug Administration. The FDA's drug review process: ensuring drugs are safe and effective [Internet]. Silver Spring (MD): FDA; [cited 2014 Dec 17]. Available from: http://www.fda.gov/drugs/resourcesforyou/consumers/ucm143534.htm
    • (2014)
  • 10
    • 85049243598 scopus 로고    scopus 로고
    • Personalized medicine and companion diagnostics go hand-in-hand [Internet]
    • Silver Spring (MD): Food and Drug Administration, Jul [cited 2014 Dec 17]. Available from
    • FDA Consumer Health Information. Personalized medicine and companion diagnostics go hand-in-hand [Internet]. Silver Spring (MD): Food and Drug Administration; 2014 Jul [cited 2014 Dec 17]. Available from: http://www.fda.gov/downloads/ForConsumers/ConsumerUpdates/UCM407452.pdf
    • (2014)
  • 11
    • 84904006604 scopus 로고    scopus 로고
    • Guidance for industry. Expedited programs for serious conditions drugs and biologics [Internet]
    • Silver Spring (MD): FDA, May [cited 2014 Dec 17], Available from
    • Food and Drug Administration. Guidance for industry. Expedited programs for serious conditions drugs and biologics [Internet]. Silver Spring (MD): FDA; 2014 May [cited 2014 Dec 17]. Available from: http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM358301.pdf
    • (2014)
  • 12
    • 84922696828 scopus 로고    scopus 로고
    • "Orphans" no more: renaissance in new drugs for rare diseases [Internet]
    • Washington (DC): ACS, May 13 [cited 2014 Dec 17]. Available from
    • American Chemical Society. "Orphans" no more: renaissance in new drugs for rare diseases [Internet]. Washington (DC): ACS; 2013 May 13 [cited 2014 Dec 17]. Available from: http://www.acs.org/content/acs/en/pressroom/newsreleases/2013/may/orphans-no-more-renaissancein-new-drugs-for-rare-diseases.html
    • (2013)
  • 13
    • 33750901702 scopus 로고    scopus 로고
    • National Childhood Vaccine Injury Act of 1986 [Internet]
    • Sterling (VA): NVIC, cited, Dec 17, Available from
    • National Vaccine Information Center. National Childhood Vaccine Injury Act of 1986 [Internet]. Sterling (VA): NVIC; [cited 2014 Dec 17]. Available from: http://www.nvic.org/Vaccine-Laws/1986-VaccineInjury-Law.aspx
    • (2014)
  • 14
    • 84922727107 scopus 로고
    • Rare Diseases Act of 2002
    • Stat
    • Rare Diseases Act of 2002, Pub. L. No. 107-280, 116 Stat. 1988-91.
    • (1988) Pub. L. , vol.116 , Issue.107-280
  • 15
    • 84922717683 scopus 로고    scopus 로고
    • GAIN: how a new law is stimulating the development of antibiotics [Internet]
    • Washington (DC): Pew Charitable Trusts, Nov 7 [cited 2014 Dec 17]. Available from
    • Pew Charitable Trusts. GAIN: how a new law is stimulating the development of antibiotics [Internet]. Washington (DC): Pew Charitable Trusts; 2013 Nov 7 [cited 2014 Dec 17]. Available from: http://www.pewtrusts.org/en/researchand-analysis/issue-briefs/2013/11/07/gain-how-a-new-law-isstimulating-the-development-ofantibiotics
    • (2013)
  • 16
    • 84922700062 scopus 로고    scopus 로고
    • SBIR Phase IIB Bridge Award [Internet]
    • Bethesda (MD): National Cancer Institute, cited, Dec 17, Available from
    • National Cancer Institute. SBIR Phase IIB Bridge Award [Internet]. Bethesda (MD): National Cancer Institute; [cited 2014 Dec 17]. Available from: http://sbir.cancer.gov/funding/phase2bridgeaward.asp#about
    • (2014)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.