DC-SCRIPT is a novel regulator of the tumor suppressor gene CDKN2B and induces cell cycle arrest in ERα-positive breast cancer cells

Breast Cancer Research and Treatment

Volumn 149, Issue 3, 2015, Pages 693-703

  Ansems, Marleen ^a   Søndergaard, Jonas Nørskov ^a   Sieuwerts, Anieta M ^b   Looman, Maaike W G ^a   Smid, Marcel ^b   de Graaf, Annemarie M A ^a   de Weerd, Vanja ^b   Zuidscherwoude, Malou ^a   Foekens, John A ^b   Martens, John W M ^b   Adema, Gosse J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MC CANCER INSTITUTE   (Netherlands)

Author keywords

Breast cancer; CDKN2B; Cell cycle; DC SCRIPT; G1 arrest; ZNF366

Indexed keywords

CYCLIN DEPENDENT KINASE 6; DOXYCYCLINE; ESTROGEN RECEPTOR ALPHA; MESSENGER RNA; CARRIER PROTEIN; CDKN2B PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 2B; ESTROGEN RECEPTOR ALPHA, HUMAN; TUMOR MARKER; TUMOR PROTEIN; ZNF366 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST CARCINOMA; CANCER CELL; CANCER GROWTH; CANCER PATIENT; CDK6 GENE; CDKN2B GENE; CELL COUNT; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL VIABILITY; CYP26B1 GENE; DC SCRIPT GENE; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE TARGETING; GROWTH INHIBITION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MAPK13 GENE; MOUSE; NONHUMAN; TUMOR SUPPRESSOR GENE; UPREGULATION; BIOSYNTHESIS; BREAST TUMOR; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; MCF 7 CELL LINE; METABOLISM; PATHOLOGY;

BIOMARKERS, TUMOR; BREAST NEOPLASMS; CARRIER PROTEINS; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P15; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; MCF-7 CELLS; NEOPLASM PROTEINS; RNA, MESSENGER;

EID: 84922631890     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-015-3281-y     Document Type: Article

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