Metabolomic serum profiling detects early-stage high-grade serous ovarian cancer in a mouse model

Journal of Proteome Research

Volumn 14, Issue 2, 2015, Pages 917-927

  Jones, Christina M ^a   Monge, María Eugenia ^a,c   Kim, Jaeyeon ^b   Matzuk, Martin M ^b   Fernández, Facundo M ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c Universidad Nacional de Río Cuarto Consejo Nacional de Investigaciones Científicas y Técnicas   (Argentina)

Author keywords

Biomarkers; early detection; Liquid chromatography; Mass spectrometry; Mouse models; Ovarian cancer; Untargeted metabolomics

Indexed keywords

BILE ACID; FATTY ACID; GLYCEROPHOSPHOLIPID; PEPTIDE; PLANT MEDICINAL PRODUCT; TUMOR MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ENERGY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; KNOCKOUT MOUSE; MASS SPECTROMETRY; MEASUREMENT ACCURACY; METABOLISM; METABOLITE; METABOLOMICS; MOUSE; MOUSE MODEL; NONHUMAN; NORMAL HUMAN; OVARY CANCER; OXIDATIVE STRESS; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; BLOOD; EARLY CANCER DIAGNOSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEAST SQUARE ANALYSIS; MALE; METABOLOME; OVARY TUMOR; PHYSIOLOGY; PROCEDURES;

MUS;

ANIMALS; BIOMARKERS, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EARLY DETECTION OF CANCER; FEMALE; HUMANS; LEAST-SQUARES ANALYSIS; MALE; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; MICE; OVARIAN NEOPLASMS;

EID: 84922614589     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5009948     Document Type: Article

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