Routine labour epidural analgesia versus labour analgesia on request: A randomised non-inferiority trial

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 122, Issue 3, 2015, Pages 344-350

  Wassen, M M L H ^a   Smits, L J M ^a   Scheepers, H C J ^a   Marcus, M A E ^a   Van Neer, J ^b   Nijhuis, J G ^a   Roumen, F J M E ^b  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Sittard Geleen Heerlen   (Netherlands)

Author keywords

Caesarean section; epidural analgesia; instrumental vaginal delivery; labour analgesia analgesia; mode of delivery; operative delivery

Indexed keywords

BUPIVACAINE; OPIATE; OXYTOCIN; ROPIVACAINE; SUFENTANIL;

ADULT; ANALGESIA; ARTICLE; BLEEDING; CESAREAN SECTION; COMPARATIVE STUDY; CONTINUOUS INFUSION; CONTROLLED STUDY; EPIDURAL ANESTHESIA; FEMALE; FEVER; GESTATION PERIOD; GESTATIONAL AGE; HEADACHE; HUMAN; HYPOTENSION; INFECTION; INSTRUMENTAL DELIVERY; INTENTION TO TREAT ANALYSIS; LABOR EPIDURAL ANALGESIA; LABOR PAIN; LABOR STAGE 2; MAJOR CLINICAL STUDY; OBSTETRIC ANALGESIA; OPEN STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; UTERINE CERVIX DILATATION; VAGINAL DELIVERY; CLINICAL TRIAL; DELIVERY; MULTICENTER STUDY; NETHERLANDS; PREGNANCY; PROCEDURES; TIME TO TREATMENT; TREATMENT OUTCOME;

ADULT; ANALGESIA, EPIDURAL; ANALGESIA, OBSTETRICAL; CESAREAN SECTION; DELIVERY, OBSTETRIC; FEMALE; HUMANS; LABOR PAIN; NETHERLANDS; PAIN MANAGEMENT; PREGNANCY; TIME-TO-TREATMENT; TREATMENT OUTCOME;

EID: 84922610820     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/1471-0528.12854     Document Type: Article

References (16)

1. Anim-Somuah M, Smyth RMD, Jones L,. Epidural versus non-epidural or no analgesia in labour. Cochrane Database Syst Rev 2011: CD000331.
2. Leighton BL, Halpern SH,. The effects of epidural analgesia on labor, maternal, and neonatal outcomes: a systematic review. Am J Obstet Gynecol 2002; 186 (5 Suppl Nature): S69-77.
3. ACOG committee opinion # 295: pain relief during labor. Obstet Gynecol 2004; 104: 213.
4. Alexander JM, Sharma SK, McIntire DD, Wiley J, Leveno KJ,. Intensity of labor pain and cesarean delivery. Anesth Analg 2001; 92: 1524-8.
5. The Netherlands Perinatal Registry. Perinatal Care in the Netherlands 2003-2009. Utrecht: The Netherlands Perinatal Registry, 2013 (In Dutch).
6. Blondel B, Supernant K, Du Mazaubrun C, Breart G,. Trends in perinatal health in metropolitan France between 1995 and 2003: results from the National Perinatal Surveys. J Gynecol Obstet Biol Reprod (Paris) 2006; 35: 373-87. (In French).
7. Vuori E, Gissler M,. Perinatal statistics: parturients, deliveries and newborns. 2012 [ www.thl.fi/en-us/web/en/statitics/topics/reproductive-health/deliveries ]. Accessed 27 September 2013.
8. Cammu H, Martens E, Martens G, Van Mol C, Jacquemyn Y,. Perinatal Activities in Flanders 2011. Brussel: Study centre Perinatal Epidemiology, 2011. (In Dutch: Perinatale activiteiten in Vlaanderen 2011. Studiecentrum voor Perinatale Epidemiologie, Brussel, SPE 2011).
9. Wassen MM, Zuijlen J, Roumen FJ, Smits LJ, Marcus MA, Nijhuis JG,. Early versus late epidural analgesia and risk on instrumental delivery in nulliparous women: a systematic review. BJOG 2011; 118: 655-61.
10. Piaggio G, Elbourne DR, Pocock SJ, Evans SJW, Altman DG,; CONSORT group. Reporting of noninferiority and equivalence randomized trials: an extension of the CONSORT 2010 statement. JAMA 2012; 308: 2594-604.
11. The Netherlands Perinatal Registry. Landelijke verloskunde registratie tweede lijn (LVR-2) 2008. Utrecht: The Netherlands Perinatal Registry, 2008.
12. Scott IA,. Non-inferiority trials: determining whether alternative treatments are good enough. Med J Aust 2009; 190: 326-30.
13. Van der Vyver M, Halpern S, Joseph G,. Patient-controlled epidural analgesia versus continuous infusion for labour analgesia: a meta-analysis. Br J Anaesth 2002; 89: 459-65.
14. George RB, Allen TK, Habib AS,. Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: a systematic review and meta-analysis. Anesth Analg 2013; 116: 133-44.
15. Gogarten W, Van de Velde M, Soetens F, Van Aken H, Brodner G, Gramke HF, et al. A multicentre trial comparing different concentrations of ropivacaine plus sufentanil with bupivacaine plus sufentanil for patient-controlled epidural analgesia in labour. Eur J Anaesthesiol 2004; 21: 38-45.
16. de Neef T,. Figures and trends of pain relief in the Netherlands. In, Slager E, editor. Reproductieve Geneeskunde, Gynaecologie en Obstetrie Anno 2013. Haarlem: DCHG, medische communicatie; 2013. pp. 882-6.