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Volumn 8, Issue 6, 2014, Pages 432-441

Characterization of a composite injury model of severe lower limb bone and nerve trauma

Author keywords

Animal model; Bone; Composite tissue trauma; Peripheral nerve; Tissue engineering; Wound healing

Indexed keywords

BIOMECHANICS; BONE; COMPUTERIZED TOMOGRAPHY; ELECTROPHYSIOLOGY;

EID: 84922482035     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1537     Document Type: Article
Times cited : (10)

References (47)
  • 1
    • 0642343446 scopus 로고    scopus 로고
    • Regulating bone formation via controlled scaffold degradation
    • Alsberg E, Kong HJ, Hirano Y et al. 2003; Regulating bone formation via controlled scaffold degradation. J Dent Res 82: 903-908.
    • (2003) J Dent Res , vol.82 , pp. 903-908
    • Alsberg, E.1    Kong, H.J.2    Hirano, Y.3
  • 2
    • 73349126425 scopus 로고    scopus 로고
    • Effect of selective sensory denervation on fracture-healing: an experimental study of rats
    • Apel PJ, Crane D, Northam CN et al. 2009; Effect of selective sensory denervation on fracture-healing: an experimental study of rats. J Bone Joint Surg Am 91: 2886-2895.
    • (2009) J Bone Joint Surg Am , vol.91 , pp. 2886-2895
    • Apel, P.J.1    Crane, D.2    Northam, C.N.3
  • 3
    • 0033046940 scopus 로고    scopus 로고
    • Targeted expression of calcitonin gene-related peptide to osteoblasts increases bone density in mice
    • Ballica R, Valentijn K, Khachatryan A et al. 1999; Targeted expression of calcitonin gene-related peptide to osteoblasts increases bone density in mice. J Bone Miner Res 14: 1067-1074.
    • (1999) J Bone Miner Res , vol.14 , pp. 1067-1074
    • Ballica, R.1    Valentijn, K.2    Khachatryan, A.3
  • 4
    • 0025112812 scopus 로고
    • The osteogenic stimulating effect of neuroactive calcitonin gene-related peptide
    • Bernard GW, Shih C. 1990; The osteogenic stimulating effect of neuroactive calcitonin gene-related peptide. Peptides 11: 625-632.
    • (1990) Peptides , vol.11 , pp. 625-632
    • Bernard, G.W.1    Shih, C.2
  • 5
    • 0023870809 scopus 로고
    • Substance P- and CGRP-immunoreactive nerves in bone
    • Bjurholm A, Kreicbergs A, Brodin E et al. 1988; Substance P- and CGRP-immunoreactive nerves in bone. Peptides 9: 165-171.
    • (1988) Peptides , vol.9 , pp. 165-171
    • Bjurholm, A.1    Kreicbergs, A.2    Brodin, E.3
  • 6
    • 84861095141 scopus 로고    scopus 로고
    • Effects of in vivo mechanical loading on large bone defect regeneration
    • Boerckel JD, Kolambkar YM, Stevens HY et al. 2012; Effects of in vivo mechanical loading on large bone defect regeneration. J Orthop Res 30(7): 1067-1075.
    • (2012) J Orthop Res , vol.30 , Issue.7 , pp. 1067-1075
    • Boerckel, J.D.1    Kolambkar, Y.M.2    Stevens, H.Y.3
  • 7
    • 0037069763 scopus 로고    scopus 로고
    • An analysis of outcomes of reconstruction or amputation after leg-threatening injuries
    • Bosse MJ, MacKenzie EJ, Kellam JF et al. 2002; An analysis of outcomes of reconstruction or amputation after leg-threatening injuries. N Engl J Med 347: 1924-1931.
    • (2002) N Engl J Med , vol.347 , pp. 1924-1931
    • Bosse, M.J.1    MacKenzie, E.J.2    Kellam, J.F.3
  • 8
    • 54049091492 scopus 로고    scopus 로고
    • CatWalk gait analysis in assessment of functional recovery after sciatic nerve injury
    • Bozkurt A, Deumens R, Scheffel J et al. 2008; CatWalk gait analysis in assessment of functional recovery after sciatic nerve injury. J Neurosci Methods 173: 91-98.
    • (2008) J Neurosci Methods , vol.173 , pp. 91-98
    • Bozkurt, A.1    Deumens, R.2    Scheffel, J.3
  • 9
    • 78651249788 scopus 로고    scopus 로고
    • Aspects of static and dynamic motor function in peripheral nerve regeneration: SSI and CatWalk gait analysis
    • Bozkurt A, Scheffel J, Brook GA et al. 2011; Aspects of static and dynamic motor function in peripheral nerve regeneration: SSI and CatWalk gait analysis. Behav Brain Res 219: 55-62.
    • (2011) Behav Brain Res , vol.219 , pp. 55-62
    • Bozkurt, A.1    Scheffel, J.2    Brook, G.A.3
  • 10
    • 0021997471 scopus 로고
    • Calcitonin gene-related peptide is a potent vasodilator
    • Brain SD, Williams TJ, Tippins JR et al. 1985; Calcitonin gene-related peptide is a potent vasodilator. Nature 313: 54-56.
    • (1985) Nature , vol.313 , pp. 54-56
    • Brain, S.D.1    Williams, T.J.2    Tippins, J.R.3
  • 11
    • 34548535885 scopus 로고    scopus 로고
    • Automatic segmentation of cortical and trabecular compartments based on a dual threshold technique for in vivo micro-CT bone analysis
    • Buie HR, Campbell GM, Klinck RJ et al. 2007; Automatic segmentation of cortical and trabecular compartments based on a dual threshold technique for in vivo micro-CT bone analysis. Bone 41: 505-515.
    • (2007) Bone , vol.41 , pp. 505-515
    • Buie, H.R.1    Campbell, G.M.2    Klinck, R.J.3
  • 12
    • 0028960715 scopus 로고
    • Lower extremity injuries in drivers of airbag-equipped automobiles: clinical and crash reconstruction correlations
    • Burgess AR, Dischinger PC, O'Quinn TD et al. 1995; Lower extremity injuries in drivers of airbag-equipped automobiles: clinical and crash reconstruction correlations. J Trauma 38: 509-516.
    • (1995) J Trauma , vol.38 , pp. 509-516
    • Burgess, A.R.1    Dischinger, P.C.2    O'Quinn, T.D.3
  • 13
    • 66049143399 scopus 로고    scopus 로고
    • Thin-film enhanced nerve guidance channels for peripheral nerve repair
    • Clements IP, Kim YT, English AW et al. 2009; Thin-film enhanced nerve guidance channels for peripheral nerve repair. Biomaterials 30: 3834-3846.
    • (2009) Biomaterials , vol.30 , pp. 3834-3846
    • Clements, I.P.1    Kim, Y.T.2    English, A.W.3
  • 14
    • 33646065652 scopus 로고    scopus 로고
    • Radial nerve injuries associated with humeral fractures
    • DeFranco MJ, Lawton JN. 2006; Radial nerve injuries associated with humeral fractures. J Hand Surg Am 31: 655-663.
    • (2006) J Hand Surg Am , vol.31 , pp. 655-663
    • DeFranco, M.J.1    Lawton, J.N.2
  • 15
    • 34250637509 scopus 로고    scopus 로고
    • The CatWalk gait analysis in assessment of both dynamic and static gait changes after adult rat sciatic nerve resection
    • Deumens R, Jaken RJ, Marcus MA et al. 2007; The CatWalk gait analysis in assessment of both dynamic and static gait changes after adult rat sciatic nerve resection. J Neurosci Methods 164: 120-130.
    • (2007) J Neurosci Methods , vol.164 , pp. 120-130
    • Deumens, R.1    Jaken, R.J.2    Marcus, M.A.3
  • 16
    • 35349005760 scopus 로고    scopus 로고
    • Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps
    • Dodla MC, Bellamkonda RV. 2008; Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps. Biomaterials 29: 33-46.
    • (2008) Biomaterials , vol.29 , pp. 33-46
    • Dodla, M.C.1    Bellamkonda, R.V.2
  • 17
    • 50949118377 scopus 로고    scopus 로고
    • Regulation of bone remodeling by the central and peripheral nervous system
    • Elefteriou F. 2008; Regulation of bone remodeling by the central and peripheral nervous system. Arch Biochem Biophys 473: 231-236.
    • (2008) Arch Biochem Biophys , vol.473 , pp. 231-236
    • Elefteriou, F.1
  • 18
    • 78650173659 scopus 로고    scopus 로고
    • Gait analysis and pain response of two rodent models of osteoarthritis
    • Ferland CE, Laverty S, Beaudry F et al. 2011; Gait analysis and pain response of two rodent models of osteoarthritis. Pharmacol Biochem Behav 97: 603-610.
    • (2011) Pharmacol Biochem Behav , vol.97 , pp. 603-610
    • Ferland, C.E.1    Laverty, S.2    Beaudry, F.3
  • 19
    • 0025294775 scopus 로고
    • Calcitonin gene-related peptide stimulates proliferation of human endothelial cells
    • Haegerstrand A, Dalsgaard CJ, Jonzon B et al. 1990; Calcitonin gene-related peptide stimulates proliferation of human endothelial cells. Proc Natl Acad Sci USA 87: 3299-3303.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3299-3303
    • Haegerstrand, A.1    Dalsgaard, C.J.2    Jonzon, B.3
  • 20
    • 0035112684 scopus 로고    scopus 로고
    • Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries
    • Hamers FP, Lankhorst AJ, van Laar TJ et al. 2001; Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries. J Neurotrauma 18: 187-201.
    • (2001) J Neurotrauma , vol.18 , pp. 187-201
    • Hamers, F.P.1    Lankhorst, A.J.2    van Laar, T.J.3
  • 21
    • 0032933281 scopus 로고    scopus 로고
    • Outcome after major trauma: 12-month and 18-month follow-up results from the Trauma Recovery Project
    • Holbrook TL, Anderson JP, Sieber WJ et al. 1999; Outcome after major trauma: 12-month and 18-month follow-up results from the Trauma Recovery Project. J Trauma 46: 765-773.
    • (1999) J Trauma , vol.46 , pp. 765-773
    • Holbrook, T.L.1    Anderson, J.P.2    Sieber, W.J.3
  • 22
    • 0028798067 scopus 로고
    • Effect of sciatic nerve section on neural ingrowth into the rat tibial fracture callus
    • Hukkanen M, Konttinen YT, Santavirta S et al. 1995; Effect of sciatic nerve section on neural ingrowth into the rat tibial fracture callus. Clin Orthop Relat Res 311: 247-257.
    • (1995) Clin Orthop Relat Res , vol.311 , pp. 247-257
    • Hukkanen, M.1    Konttinen, Y.T.2    Santavirta, S.3
  • 23
    • 0027311068 scopus 로고
    • Rapid proliferation of calcitonin gene-related peptide-immunoreactive nerves during healing of rat tibial fracture suggests neural involvement in bone growth and remodelling
    • Hukkanen M, Konttinen YT, Santavirta S et al. 1993; Rapid proliferation of calcitonin gene-related peptide-immunoreactive nerves during healing of rat tibial fracture suggests neural involvement in bone growth and remodelling. Neuroscience 54: 969-979.
    • (1993) Neuroscience , vol.54 , pp. 969-979
    • Hukkanen, M.1    Konttinen, Y.T.2    Santavirta, S.3
  • 24
    • 0037098914 scopus 로고    scopus 로고
    • Neuronal regulation of bone metabolism and anabolism: calcitonin gene-related peptide-, substance P-, and tyrosine hydroxylase-containing nerves and the bone
    • Imai S, Matsusue Y. 2002; Neuronal regulation of bone metabolism and anabolism: calcitonin gene-related peptide-, substance P-, and tyrosine hydroxylase-containing nerves and the bone. Microsc Res Tech 58: 61-69.
    • (2002) Microsc Res Tech , vol.58 , pp. 61-69
    • Imai, S.1    Matsusue, Y.2
  • 25
    • 43149106918 scopus 로고    scopus 로고
    • The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps
    • Kim YT, Haftel VK, Kumar S et al. 2008; The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps. Biomaterials 29: 3117-3127.
    • (2008) Biomaterials , vol.29 , pp. 3117-3127
    • Kim, Y.T.1    Haftel, V.K.2    Kumar, S.3
  • 26
    • 78349309536 scopus 로고    scopus 로고
    • An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects
    • Kolambkar YM, Dupont KM, Boerckel JD et al. 2011; An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects. Biomaterials 32: 65-74.
    • (2011) Biomaterials , vol.32 , pp. 65-74
    • Kolambkar, Y.M.1    Dupont, K.M.2    Boerckel, J.D.3
  • 27
    • 14744288038 scopus 로고    scopus 로고
    • The assessment of locomotor function in spinal cord injured rats: the importance of objective analysis of coordination
    • Koopmans GC, Deumens R, Honig WM et al. 2005; The assessment of locomotor function in spinal cord injured rats: the importance of objective analysis of coordination. J Neurotrauma 22: 214-225.
    • (2005) J Neurotrauma , vol.22 , pp. 214-225
    • Koopmans, G.C.1    Deumens, R.2    Honig, W.M.3
  • 28
    • 0037008424 scopus 로고    scopus 로고
    • Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur
    • Mach DB, Rogers SD, Sabino MC et al. 2002; Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience 113: 155-166.
    • (2002) Neuroscience , vol.113 , pp. 155-166
    • Mach, D.B.1    Rogers, S.D.2    Sabino, M.C.3
  • 29
    • 23044435924 scopus 로고    scopus 로고
    • Long-term persistence of disability following severe lower-limb trauma. Results of a seven-year follow-up
    • MacKenzie EJ, Bosse MJ, Pollak AN et al. 2005; Long-term persistence of disability following severe lower-limb trauma. Results of a seven-year follow-up. J Bone Joint Surg Am 87: 1801-1809.
    • (2005) J Bone Joint Surg Am , vol.87 , pp. 1801-1809
    • MacKenzie, E.J.1    Bosse, M.J.2    Pollak, A.N.3
  • 30
    • 34547788641 scopus 로고    scopus 로고
    • Health-care costs associated with amputation or reconstruction of a limb-threatening injury
    • MacKenzie EJ, Jones AS, Bosse MJ et al. 2007; Health-care costs associated with amputation or reconstruction of a limb-threatening injury. J Bone Joint Surg Am 89: 1685-1692.
    • (2007) J Bone Joint Surg Am , vol.89 , pp. 1685-1692
    • MacKenzie, E.J.1    Jones, A.S.2    Bosse, M.J.3
  • 31
    • 0025955394 scopus 로고
    • Changes in nerve fiber numbers distal to a nerve repair in the rat sciatic nerve model
    • Mackinnon SE, Dellon AL, O'Brien JP. 1991; Changes in nerve fiber numbers distal to a nerve repair in the rat sciatic nerve model. Muscle Nerve 14: 1116-1122.
    • (1991) Muscle Nerve , vol.14 , pp. 1116-1122
    • Mackinnon, S.E.1    Dellon, A.L.2    O'Brien, J.P.3
  • 32
    • 0031780548 scopus 로고    scopus 로고
    • Fracture healing and callus innervation after peripheral nerve resection in rats
    • Madsen JE, Hukkanen M, Aune AK et al. 1998; Fracture healing and callus innervation after peripheral nerve resection in rats. Clin Orthop Relat Res 351: 230-240.
    • (1998) Clin Orthop Relat Res , vol.351 , pp. 230-240
    • Madsen, J.E.1    Hukkanen, M.2    Aune, A.K.3
  • 33
    • 66149119453 scopus 로고    scopus 로고
    • Resource utilization and disability outcome assessment of combat casualties from Operation Iraqi Freedom and Operation Enduring Freedom
    • Masini BD, Waterman SM, Wenke JC et al. 2009; Resource utilization and disability outcome assessment of combat casualties from Operation Iraqi Freedom and Operation Enduring Freedom. J Orthop Trauma 23: 261-266.
    • (2009) J Orthop Trauma , vol.23 , pp. 261-266
    • Masini, B.D.1    Waterman, S.M.2    Wenke, J.C.3
  • 34
    • 0028362334 scopus 로고
    • The neuronal regulation of fracture healing. Effects of sciatic nerve resection in rat tibia
    • Nordsletten L, Madsen JE, Almaas R et al. 1994; The neuronal regulation of fracture healing. Effects of sciatic nerve resection in rat tibia. Acta Orthop Scand 65: 299-304.
    • (1994) Acta Orthop Scand , vol.65 , pp. 299-304
    • Nordsletten, L.1    Madsen, J.E.2    Almaas, R.3
  • 35
    • 34447253328 scopus 로고    scopus 로고
    • Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects
    • Oest ME, Dupont KM, Kong HJ et al. 2007; Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects. J Orthop Res 25: 941-950.
    • (2007) J Orthop Res , vol.25 , pp. 941-950
    • Oest, M.E.1    Dupont, K.M.2    Kong, H.J.3
  • 36
    • 34247156602 scopus 로고    scopus 로고
    • Characterization of extremity wounds in operation Iraqi Freedom and operation Enduring Freedom
    • Owens BD, Kragh JF Jr, Macaitis J et al. 2007; Characterization of extremity wounds in operation Iraqi Freedom and operation Enduring Freedom. J Orthop Trauma 21: 254-257.
    • (2007) J Orthop Trauma , vol.21 , pp. 254-257
    • Owens, B.D.1    Kragh Jr, J.F.2    Macaitis, J.3
  • 37
    • 43149122483 scopus 로고    scopus 로고
    • Combat wounds in operation Iraqi Freedom and operation Enduring Freedom
    • Owens BD, Kragh JF Jr, Wenke JC et al. 2008; Combat wounds in operation Iraqi Freedom and operation Enduring Freedom. J Trauma 64: 295-299.
    • (2008) J Trauma , vol.64 , pp. 295-299
    • Owens, B.D.1    Kragh Jr, J.F.2    Wenke, J.C.3
  • 38
    • 14744286141 scopus 로고    scopus 로고
    • Improvements in passive car safety led to decreased injury severity - a comparison between the 1970s and 1990s
    • Richter M, Pape HC, Otte D et al. 2005; Improvements in passive car safety led to decreased injury severity - a comparison between the 1970s and 1990s. Injury 36: 484-488.
    • (2005) Injury , vol.36 , pp. 484-488
    • Richter, M.1    Pape, H.C.2    Otte, D.3
  • 39
  • 40
    • 84944495904 scopus 로고
    • A theory of the effects of fibre size in medullated nerve
    • Rushton WA. 1951; A theory of the effects of fibre size in medullated nerve. J Physiol 115: 101-122.
    • (1951) J Physiol , vol.115 , pp. 101-122
    • Rushton, W.A.1
  • 41
    • 50249185592 scopus 로고    scopus 로고
    • Functional adaptation to loading of a single bone is neuronally regulated and involves multiple bones
    • Sample SJ, Behan M, Smith L et al. 2008; Functional adaptation to loading of a single bone is neuronally regulated and involves multiple bones. J Bone Miner Res 23: 1372-1381.
    • (2008) J Bone Miner Res , vol.23 , pp. 1372-1381
    • Sample, S.J.1    Behan, M.2    Smith, L.3
  • 42
    • 0442292141 scopus 로고    scopus 로고
    • Emerging neuroskeletal signalling pathways: a review
    • Spencer GJ, Hitchcock IS, Genever PG. 2004; Emerging neuroskeletal signalling pathways: a review. FEBS Lett 559: 6-12.
    • (2004) FEBS Lett , vol.559 , pp. 6-12
    • Spencer, G.J.1    Hitchcock, I.S.2    Genever, P.G.3
  • 43
    • 77955299009 scopus 로고    scopus 로고
    • Automated quantitative gait analysis in animal models of movement disorders
    • Vandeputte C, Taymans JM, Casteels C et al. 2010; Automated quantitative gait analysis in animal models of movement disorders. BMC Neurosci 11: 92.
    • (2010) BMC Neurosci , vol.11 , pp. 92
    • Vandeputte, C.1    Taymans, J.M.2    Casteels, C.3
  • 44
    • 5644273227 scopus 로고    scopus 로고
    • Sciatic nerve regeneration in mice and rats: recovery of sensory innervation is followed by a slowly retreating neuropathic pain-like syndrome
    • Vogelaar CF, Vrinten DH, Hoekman MF et al. 2004; Sciatic nerve regeneration in mice and rats: recovery of sensory innervation is followed by a slowly retreating neuropathic pain-like syndrome. Brain Res 1027: 67-72.
    • (2004) Brain Res , vol.1027 , pp. 67-72
    • Vogelaar, C.F.1    Vrinten, D.H.2    Hoekman, M.F.3
  • 45
    • 79951698211 scopus 로고    scopus 로고
    • Fluoxetine increases hippocampal neurogenesis and induces epigenetic factors but does not improve functional recovery after traumatic brain injury
    • Wang Y, Neumann M, Hansen K et al. 2011; Fluoxetine increases hippocampal neurogenesis and induces epigenetic factors but does not improve functional recovery after traumatic brain injury. J Neurotrauma 28: 259-268.
    • (2011) J Neurotrauma , vol.28 , pp. 259-268
    • Wang, Y.1    Neumann, M.2    Hansen, K.3
  • 46
    • 32844463801 scopus 로고    scopus 로고
    • Neuropathy-induced osteopenia in rats is not due to a reduction in weight born on the affected limb
    • Whiteside GT, Boulet JM, Sellers R et al. 2006; Neuropathy-induced osteopenia in rats is not due to a reduction in weight born on the affected limb. Bone 38: 387-393.
    • (2006) Bone , vol.38 , pp. 387-393
    • Whiteside, G.T.1    Boulet, J.M.2    Sellers, R.3
  • 47
    • 14944362356 scopus 로고    scopus 로고
    • One-stage reconstruction of composite bone and soft-tissue defects in traumatic lower extremities
    • Yazar S, Lin CH, Wei FC. 2004; One-stage reconstruction of composite bone and soft-tissue defects in traumatic lower extremities. Plast Reconstr Surg 114: 1457-1466.
    • (2004) Plast Reconstr Surg , vol.114 , pp. 1457-1466
    • Yazar, S.1    Lin, C.H.2    Wei, F.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.