A zebrafish model exemplifies the long preclinical period of motor neuron disease

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 85, Issue 11, 2014, Pages 1288-1289

  Ramesh, Tennore M ^a   Shaw, Pamela J ^a   McDearmid, Jonathan ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL; HUMAN; PATHOLOGY; PRODROMAL SYMPTOM;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; HUMANS; PRODROMAL SYMPTOMS;

EID: 84922481732     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp-2014-308288     Document Type: Letter

References (4)

1. Eisen A, Kiernan M, Mitsumoto H, et al. Amyotrophic lateral sclerosis: a long preclinical period? J Neurol Neurosurg Psychiatry 2014;85:1232-8.
2. Ramesh T, Lyon AN, Pineda RH, et al. A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease. Dis Model Mech 2010;3:652-62.
3. McGown A, McDearmid JR, Panagiotaki N, et al. Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish model. Ann Neurol 2013;73:246-58.
4. Batulan Z, Shinder GA, Minotti S, et al. High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1. J Neurosci 2003;23:5789-98.