A small molecule binding HMGB1 and HMGB2 inhibits microglia-mediated neuroinflammation

Nature chemical biology

Volumn 10, Issue 12, 2014, Pages 1055-1060

  Lee, Sanghee ^a   Nam, Youngpyo ^a   Koo, Ja Y oung ^a   Lim, Donghyun ^a   Park, Jongmin ^a   Ock, Jiyeon ^a   Kim, Jaehong ^a   Suk, Kyoungho ^a   Park, Seung B um ^a  

^a Kyungpook National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FUSED HETEROCYCLIC RINGS; HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP B2 PROTEIN; HMGB1 PROTEIN, MOUSE; INFLACHROMENE; LIPOPOLYSACCHARIDE; NEUROPROTECTIVE AGENT; PROTEIN BINDING; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; BIOSYNTHESIS; BRAIN; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED; COCULTURE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; IMMUNOLOGY; IMMUNOMODULATION; INFLAMMATION; MALE; METABOLISM; MICROGLIA; MOUSE; NERVE CELL; PATHOLOGY; PROTEIN PROCESSING;

ANIMALS; BRAIN; CELL LINE; COCULTURE TECHNIQUES; GENE EXPRESSION; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HMGB1 PROTEIN; HMGB2 PROTEIN; INFLAMMATION; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED C57BL; MICROGLIA; NEUROIMMUNOMODULATION; NEURONS; NEUROPROTECTIVE AGENTS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84922479862     PISSN: None     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1669     Document Type: Article

References (0)