Biomarkers: More than just markers!

Nephrology Dialysis Transplantation

Volumn 30, Issue 1, 2015, Pages 33-38

  Haase, Michael ^a   Mertens, Peter R ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

acute kidney injury; chemotaxis; kidney injury molecule 1; renal fibrosis; unilateral ureteral obstruction

Indexed keywords

ALKALINE PHOSPHATASE; BIOLOGICAL MARKER; CYSTATIN C; INTERLEUKIN 18; INTERLEUKIN 6; KIDNEY INJURY MOLECULE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN MOLECULE 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; MEMBRANE PROTEIN;

ACUTE KIDNEY FAILURE; CHRONIC KIDNEY DISEASE; CYTOKINE RELEASE; EARLY DIAGNOSIS; HUMAN; INTERSTITIAL NEPHRITIS; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY ISCHEMIA; NONHUMAN; PLASMA CELL DYSCRASIA; PROGNOSIS; PROTEINURIA; REVIEW; SARCOIDOSIS; URETER OBSTRUCTION; ANIMAL; CHRONIC KIDNEY FAILURE; KIDNEY; METABOLISM;

ANIMALS; KIDNEY; KIDNEY FAILURE, CHRONIC; MEMBRANE PROTEINS;

EID: 84922464456     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfu085     Document Type: Review

References (26)

1. Humphreys BD, Xu F, Sabbisetti V et al. Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. J Clin Invest 2013; 123: 4023-4035
2. Mehta RL, Kellum JA, Shah SV et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007; 11: R31
3. McCullough PA, Shaw AD, Haase M et al. Diagnosis of acute kidney injury using functional and injury biomarkers: workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference. Contrib Nephrol 2013; 182: 13-29
4. Zhang Z, Lu B, Sheng X et al. Cystatin C in prediction of acute kidney injury: a systemic review and meta-Analysis. Am J Kidney Dis 2011; 58: 356-365
5. Lieske JC, Chawla L, Kashani K et al. Biomarkers for acute kidney injury: where are we today? Where should we go? Clin Chem 2014; 60: 294-300
6. McCullough PA, Bouchard J, Waikar SS et al. Implementation of novel biomarkers in the diagnosis, prognosis, and management of acute kidney injury: executive summary from the tenth consensus conference of the Acute Dialysis Quality Initiative (ADQI). Contrib Nephrol 2013; 182: 5-12
7. Goldstein SL, Chawla LS. Renal angina. Clin J Am Soc Nephrol 2010; 5: 943-949
8. Coca SG. Is it AKI or nonrecovery of renal function that is important for long-term outcomes? Clin J Am Soc Nephrol 2012; 8: 173-176
9. Coca SG, Garg AX, Thiessen-Philbrook H et al. (December 19, 2013) Urinary biomarkers of AKI and mortality 3 years after cardiac surgery. J Am Soc Nephrol. doi: 10.1681/ASN.2013070742 [Epub ahead of print]
10. Ishani A, Xue JL, Himmelfarb J et al. Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol 2009; 20: 223-228
11. Bucaloiu ID, Kirchner HL, Norfolk ER et al. Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury. Kidney Int 2012; 81: 477-485
12. Kuehn EW, Park KM, Somlo S et al. Kidney injury molecule-1 expression in murine polycystic kidney disease. Am J Physiol Renal Physiol 2002; 283: F1326-F1336
13. Huby AC, Kavvadas P, Alfieri C et al. The RenTg mice: a powerful tool to study renin-dependent chronic kidney disease. PLoS ONE 2012; 7: e52362
14. Kobayashi A, Valerius MT, Mugford JW et al. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell 2008; 3: 169-181
15. Ichimura T, Bonventre JV, Bailly V et al. Kidney injury molecule-1 (KIM- 1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J Biol Chem 1998; 273: 4135-4142
16. Feng BS, Chen X, He SH et al. Disruption of T-cell immunoglobulin and mucin domain molecule (TIM)-1/TIM4 interaction as a therapeutic strategy in a dendritic cell-induced peanut allergy model. J Allergy Clin Immunol 2008; 122: 55-61, 61 e1-7
17. Fukushima A, Sumi T, Fukuda K et al. Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis. Biochem Biophys Res Commun 2007; 353: 211-216
18. Lucas M, Stuart LM, Savill J et al. Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion. J Immunol 2003; 171: 2610-2615
19. Sonar SS, Hsu YM, Conrad ML et al. Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma. J Clin Invest 2010; 120: 2767-2781
20. Rennert PD. Novel roles for TIM-1 in immunity and infection. Immunol Lett 2011; 141: 28-35
21. Ichimura T, Asseldonk EJ, Humphreys BD et al. Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest 2008; 118: 1657-1668
22. Rees AJ, Kain R. Kim-1/Tim-1: from biomarker to therapeutic target? Nephrol Dial Transplant 2008; 23: 3394-3396
23. de Geus HR, Fortrie G, Betjes MG et al. Time of injury affects urinary biomarker predictive values for acute kidney injury in critically ill, non-septic patients. BMC Nephrol 2013; 14: 273
24. HanWK, Bailly V, Abichandani R et al. Kidney InjuryMolecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int 2002; 62: 237-244
25. Han WK, Waikar SS, Johnson A et al. Urinary biomarkers in the early diagnosis of acute kidney injury. Kidney Int 2008; 73: 863-869
26. Liang XL, Liu SX, Chen YH et al. Combination of urinary kidney injury molecule-1 and interleukin-18 as early biomarker for the diagnosis and progressive assessment of acute kidney injury following cardiopulmonary bypass surgery: a prospective nested case-control study. Biomarkers 2010; 15: 332-339