메뉴 건너뛰기




Volumn 70, Issue 2, 2015, Pages 225-231

Platelet-monocyte aggregate formation and mortality risk in older patients with severe sepsis and septic shock

Author keywords

Inflammation; Mortality; Platelet; Platelet monocyte aggregates; Sepsis

Indexed keywords

BIOLOGICAL MARKER; INTERLEUKIN 6; INTERLEUKIN 8;

EID: 84922464391     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glu082     Document Type: Article
Times cited : (64)

References (36)
  • 1
    • 79953305437 scopus 로고    scopus 로고
    • The septic milieu triggers expression of spliced tissue factor mRNA in human platelets
    • Rondina MT, Schwertz H, Harris ES, et al. The septic milieu triggers expression of spliced tissue factor mRNA in human platelets. J Thromb Haemost. 2011; 9: 748-758. doi: 10.1111/j.1538-7836.2011.04208.x
    • (2011) J Thromb Haemost. , vol.9 , pp. 748-758
    • Rondina, M.T.1    Schwertz, H.2    Harris, E.S.3
  • 3
    • 79952989700 scopus 로고    scopus 로고
    • Pathogen sensing, subsequent signalling, and signalosome in human platelets
    • Garraud O, Berthet J, Hamzeh-Cognasse H, Cognasse F. Pathogen sensing, subsequent signalling, and signalosome in human platelets. Thromb Res. 2011; 127: 283-286. doi: 10.1016/j.thromres.2010.10.015
    • (2011) Thromb Res. , vol.127 , pp. 283-286
    • Garraud, O.1    Berthet, J.2    Hamzeh-Cognasse, H.3    Cognasse, F.4
  • 4
    • 0035949524 scopus 로고    scopus 로고
    • Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: Studies in baboons, human coronary intervention, and human acute myocardial infarction
    • Michelson AD, Barnard MR, Krueger LA, Valeri CR, Furman MI. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation. 2001; 104: 1533-1537.
    • (2001) Circulation , vol.104 , pp. 1533-1537
    • Michelson, A.D.1    Barnard, M.R.2    Krueger, L.A.3    Valeri, C.R.4    Furman, M.I.5
  • 5
    • 84861333498 scopus 로고    scopus 로고
    • Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques
    • Rondina MT, Grissom CK, Men S, et al. Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques. Thromb Res. 2012; 129: 729-735. doi: 10.1016/j.thromres.2011.11.031
    • (2012) Thromb Res. , vol.129 , pp. 729-735
    • Rondina, M.T.1    Grissom, C.K.2    Men, S.3
  • 6
    • 0029993531 scopus 로고    scopus 로고
    • Activated platelets signal chemokine synthesis by human monocytes
    • Weyrich AS, Elstad MR, McEver RP, et al. Activated platelets signal chemokine synthesis by human monocytes. J Clin Invest. 1996; 97: 1525-1534.
    • (1996) J Clin Invest , vol.97 , pp. 1525-1534
    • Weyrich, A.S.1    Elstad, M.R.2    McEver, R.P.3
  • 7
    • 15044359591 scopus 로고    scopus 로고
    • Insights into severe sepsis in older patients: From epidemiology to evidence-based management
    • Girard TD, Opal SM, Ely EW. Insights into severe sepsis in older patients: from epidemiology to evidence-based management. Clin Infect Dis. 2005; 40: 719-727.
    • (2005) Clin Infect Dis , vol.40 , pp. 719-727
    • Girard, T.D.1    Opal, S.M.2    Ely, E.W.3
  • 8
    • 29744447480 scopus 로고    scopus 로고
    • The effect of age on the development and outcome of adult sepsis
    • Martin GS, Mannino DM, Moss M. The effect of age on the development and outcome of adult sepsis. Crit Care Med. 2006; 34: 15-21.
    • (2006) Crit Care Med , vol.34 , pp. 15-21
    • Martin, G.S.1    Mannino, D.M.2    Moss, M.3
  • 9
    • 63049100253 scopus 로고    scopus 로고
    • Pathophysiology of sepsis in the elderly: Clinical impact and therapeutic considerations
    • De Gaudio AR, Rinaldi S, Chelazzi C, Borracci T. Pathophysiology of sepsis in the elderly: clinical impact and therapeutic considerations. Curr Drug Targets. 2009; 10: 60-70.
    • (2009) Curr Drug Targets , vol.10 , pp. 60-70
    • De Gaudio, A.R.1    Rinaldi, S.2    Chelazzi, C.3    Borracci, T.4
  • 10
    • 84875969526 scopus 로고    scopus 로고
    • A prognostic model for 6-month mortality in elderly survivors of critical illness
    • Baldwin MR, Narain WR, Wunsch H, et al. A prognostic model for 6-month mortality in elderly survivors of critical illness. Chest. 2013; 143: 910-919. doi: 10.1378/chest.12-1668
    • (2013) Chest , vol.143 , pp. 910-919
    • Baldwin, M.R.1    Narain, W.R.2    Wunsch, H.3
  • 11
    • 77953669656 scopus 로고    scopus 로고
    • Age-dependent alterations of monocyte subsets and monocyterelated chemokine pathways in healthy adults
    • Seidler S, Zimmermann HW, Bartneck M, Trautwein C, Tacke F. Age-dependent alterations of monocyte subsets and monocyterelated chemokine pathways in healthy adults. BMC Immunol. 2010; 11: 30. doi: 10.1186/1471-2172-11-30
    • (2010) BMC Immunol. , vol.11 , pp. 30
    • Seidler, S.1    Zimmermann, H.W.2    Bartneck, M.3    Trautwein, C.4    Tacke, F.5
  • 13
    • 84888320636 scopus 로고    scopus 로고
    • Age-dependent dysregulation of innate immunity
    • Shaw AC, Goldstein DR, Montgomery RR. Age-dependent dysregulation of innate immunity. Nat Rev Immunol. 2013; 13: 875-887. doi: 10.1038/nri3547
    • (2013) Nat Rev Immunol. , vol.13 , pp. 875-887
    • Shaw, A.C.1    Goldstein, D.R.2    Montgomery, R.R.3
  • 14
    • 33646686146 scopus 로고    scopus 로고
    • Oxidative damage and platelet activation as new predictors of mobility disability and mortality in elders
    • Cesari M, Kritchevsky SB, Leeuwenburgh C, Pahor M. Oxidative damage and platelet activation as new predictors of mobility disability and mortality in elders. Antioxid Redox Signal. 2006; 8: 609-619.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 609-619
    • Cesari, M.1    Kritchevsky, S.B.2    Leeuwenburgh, C.3    Pahor, M.4
  • 15
    • 0022446534 scopus 로고
    • Increased thromboxane biosynthesis in a human preparation of platelet activation: Biochemical and functional consequences of selective inhibition of thromboxane synthase
    • Reilly IA, Doran JB, Smith B, FitzGerald GA. Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase. Circulation. 1986; 73: 1300-1309.
    • (1986) Circulation , vol.73 , pp. 1300-1309
    • Reilly, I.A.1    Doran, J.B.2    Smith, B.3    Fitzgerald, G.A.4
  • 16
    • 84896404308 scopus 로고    scopus 로고
    • Alterations in platelet function during aging: Clinical correlations with thromboinflammatory disease in older adults
    • Mohebali D, Kaplan D, Carlisle M, Supiano MA, Rondina MT. Alterations in platelet function during aging: clinical correlations with thromboinflammatory disease in older adults. J Am Geriatr Soc. 2014; 62: 529-535. doi: 10.1111/jgs.12700
    • (2014) J Am Geriatr Soc. , vol.62 , pp. 529-535
    • Mohebali, D.1    Kaplan, D.2    Carlisle, M.3    Supiano, M.A.4    Rondina, M.T.5
  • 17
    • 0026874127 scopus 로고
    • American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
    • Bone RC, Balk RA, Cerra FB, et al. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992; 20: 864-874.
    • (1992) Crit Care Med , vol.20 , pp. 864-874
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3
  • 18
    • 84862023500 scopus 로고    scopus 로고
    • In vivo platelet activation in critically ill patients with primary 2009 influenza a (H1N1)
    • Rondina MT, Brewster B, Grissom CK, et al. In Vivo Platelet Activation in Critically Ill Patients With Primary 2009 Influenza A (H1N1). Chest. 2012, 141: 1490-1495. doi: 10.1378/chest.11-2860
    • (2012) Chest , vol.141 , pp. 1490-1495
    • Rondina, M.T.1    Brewster, B.2    Grissom, C.K.3
  • 19
    • 84878659017 scopus 로고    scopus 로고
    • Platelets as cellular effectors of inflammation in vascular diseases
    • Rondina MT, Weyrich AS, Zimmerman GA. Platelets as cellular effectors of inflammation in vascular diseases. Circ Res. 2013; 112: 1506-1519. doi: 10.1161/CIRCRESAHA.113.300512
    • (2013) Circ Res , vol.112 , pp. 1506-1519
    • Rondina, M.T.1    Weyrich, A.S.2    Zimmerman, G.A.3
  • 22
    • 39449095307 scopus 로고    scopus 로고
    • Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes
    • Schmidt R, Bultmann A, Fischel S, et al. Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes. Circ Res. 2008; 102: 302-309.
    • (2008) Circ Res , vol.102 , pp. 302-309
    • Schmidt, R.1    Bultmann, A.2    Fischel, S.3
  • 23
    • 34249318067 scopus 로고    scopus 로고
    • Cytokine profiles as markers of disease severity in sepsis: A multiplex analysis
    • Bozza FA, Salluh JI, Japiassu AM, et al. Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis. Crit Care. 2007; 11: R49.
    • (2007) Crit Care , vol.11 , pp. R49
    • Bozza, F.A.1    Salluh, J.I.2    Japiassu, A.M.3
  • 24
    • 0016440823 scopus 로고
    • Sex and age differences in human platelet aggregation
    • Johnson M, Ramey E, Ramwell PW. Sex and age differences in human platelet aggregation. Nature. 1975; 253: 355-357.
    • (1975) Nature , vol.253 , pp. 355-357
    • Johnson, M.1    Ramey, E.2    Ramwell, P.W.3
  • 25
    • 0019416358 scopus 로고
    • Evaluation of some platelet parameters in a group of elderly people
    • Sie P, Montagut J, Blanc M, et al. Evaluation of some platelet parameters in a group of elderly people. Thromb Haemost. 1981; 45: 197-199.
    • (1981) Thromb Haemost , vol.45 , pp. 197-199
    • Sie, P.1    Montagut, J.2    Blanc, M.3
  • 26
    • 0027265827 scopus 로고
    • Increased cytokine production in mononuclear cells of healthy elderly people
    • Fagiolo U, Cossarizza A, Scala E, et al. Increased cytokine production in mononuclear cells of healthy elderly people. Eur J Immunol. 1993; 23: 2375-2378.
    • (1993) Eur J Immunol , vol.23 , pp. 2375-2378
    • Fagiolo, U.1    Cossarizza, A.2    Scala, E.3
  • 27
    • 84857554756 scopus 로고    scopus 로고
    • Temporal trends in patient characteristics and survival of intensive care admissions with sepsis: A multicenter analysis
    • Dreiher J, Almog Y, Sprung CL, et al.; SEPSIS-ISR Group. Temporal trends in patient characteristics and survival of intensive care admissions with sepsis: a multicenter analysis. Crit Care Med. 2012; 40: 855-860. doi: 10.1097/CCM.0b013e318236f7b8
    • (2012) Crit Care Med. , vol.40 , pp. 855-860
    • Dreiher, J.1    Almog, Y.2    Sprung, C.L.3
  • 28
    • 0037035464 scopus 로고    scopus 로고
    • Platelet-monocyte aggregates: Bridging thrombosis and inflammation
    • Freedman JE, Loscalzo J. Platelet-monocyte aggregates: bridging thrombosis and inflammation. Circulation. 2002; 105: 2130-2132.
    • (2002) Circulation , vol.105 , pp. 2130-2132
    • Freedman, J.E.1    Loscalzo, J.2
  • 29
    • 13444281904 scopus 로고    scopus 로고
    • Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates
    • Weyrich AS, Denis MM, Kuhlmann-Eyre JR, et al. Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates. Circulation. 2005; 111: 633-642.
    • (2005) Circulation , vol.111 , pp. 633-642
    • Weyrich, A.S.1    Denis, M.M.2    Kuhlmann-Eyre, J.R.3
  • 30
    • 0034805421 scopus 로고    scopus 로고
    • Circulating monocyteplatelet aggregates are an early marker of acute myocardial infarction
    • Furman MI, Barnard MR, Krueger LA, et al. Circulating monocyteplatelet aggregates are an early marker of acute myocardial infarction. J Am Coll Cardiol. 2001; 38: 1002-1006.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 1002-1006
    • Furman, M.I.1    Barnard, M.R.2    Krueger, L.A.3
  • 31
    • 84856686739 scopus 로고    scopus 로고
    • Upregulation of CD40 ligand and enhanced monocyte-platelet aggregate formation are associated with worse clinical outcome after ischaemic stroke
    • Lukasik M, Dworacki G, Kufel-Grabowska J, Watala C, Kozubski W. Upregulation of CD40 ligand and enhanced monocyte-platelet aggregate formation are associated with worse clinical outcome after ischaemic stroke. Thromb Haemost. 2012; 107: 346-355. doi: 10.1160/TH11-05-0345
    • (2012) Thromb Haemost. , vol.107 , pp. 346-355
    • Lukasik, M.1    Dworacki, G.2    Kufel-Grabowska, J.3    Watala, C.4    Kozubski, W.5
  • 32
    • 84856381402 scopus 로고    scopus 로고
    • A combined score of pro- and anti-inflammatory interleukins improves mortality prediction in severe sepsis
    • Andaluz-Ojeda D, Bobillo F, Iglesias V, et al. A combined score of pro- and anti-inflammatory interleukins improves mortality prediction in severe sepsis. Cytokine. 2012; 57: 332-336. doi: 10.1016/j. cyto.2011.12.002
    • (2012) Cytokine , vol.57 , pp. 332-336
    • Andaluz-Ojeda, D.1    Bobillo, F.2    Iglesias, V.3
  • 33
    • 79953202811 scopus 로고    scopus 로고
    • Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury
    • National Heart Blood and Lung Institute Acute Respiratory Distress Syndrome Network
    • Calfee CS, Ware LB, Glidden DV, et al.; National Heart, Blood, and Lung Institute Acute Respiratory Distress Syndrome Network. Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury. Crit Care Med. 2011; 39: 711-717. doi: 10.1097/CCM.0b013e318207ec3c
    • (2011) Crit Care Med , vol.39 , pp. 711-717
    • Calfee, C.S.1    Ware, L.B.2    Glidden, D.V.3
  • 34
    • 0036068710 scopus 로고    scopus 로고
    • Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: A pilot study
    • Leng S, Chaves P, Koenig K, Walston J. Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study. J Am Geriatr Soc. 2002; 50: 1268-1271.
    • (2002) J Am Geriatr Soc , vol.50 , pp. 1268-1271
    • Leng, S.1    Chaves, P.2    Koenig, K.3    Walston, J.4
  • 35
    • 0037374428 scopus 로고    scopus 로고
    • Clopidogrel but not aspirin reduces P-selectin expression and formation of platelet-leukocyte aggregates in patients with atherosclerotic vascular disease
    • Klinkhardt U, Bauersachs R, Adams J, Graff J, Lindhoff-Last E, Harder S. Clopidogrel but not aspirin reduces P-selectin expression and formation of platelet-leukocyte aggregates in patients with atherosclerotic vascular disease. Clin Pharmacol Ther. 2003; 73: 232-241.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 232-241
    • Klinkhardt, U.1    Bauersachs, R.2    Adams, J.3    Graff, J.4    Lindhoff-Last, E.5    Harder, S.6
  • 36
    • 17144392613 scopus 로고    scopus 로고
    • Total and differential white blood cell counts and their associations with circulating interleukin-6 levels in community-dwelling older women
    • Leng S, Xue QL, Huang Y, et al. Total and differential white blood cell counts and their associations with circulating interleukin-6 levels in community-dwelling older women. J Gerontol A Biol Sci Med Sci. 2005; 60: 195-199.
    • (2005) J Gerontol A Biol Sci Med Sci , vol.60 , pp. 195-199
    • Leng, S.1    Xue, Q.L.2    Huang, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.