Transient CD15-positive endothelial phenotype in the human placenta correlates with physiological and pathological fetoplacental immaturity

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 180, Issue 1, 2014, Pages 172-179

  Seidmann, L ^a   Suhan, T ^a   Unger, R ^a   Gerein, V ^b   Kirkpatrick, C J ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

CD15; Diagnostic marker; Endothelium; Hematopoiesis; Placental pathologies; Villous immaturity

Indexed keywords

CD15 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; FUCOSYLTRANSFERASE; FUT4 PROTEIN, HUMAN; PTPRC PROTEIN, HUMAN;

ANTIGEN EXPRESSION; ARTICLE; CELL COUNT; CHORION VILLUS; CHORION VILLUS IMMATURITY; COMPARATIVE STUDY; CONTROLLED STUDY; EMBRYONIC AND PLACENTAL STRUCTURES; ENDOTHELIUM CELL; ERYTHROBLAST; FEMALE; FETOPLACENTAL IMMATURITY; FETUS BLOOD; FETUS DEATH; FETUS HYPOXIA; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HELLP SYNDROME; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMATURITY; IMMUNOHISTOCHEMISTRY; PHENOTYPE; PLACENTA DEVELOPMENT; PLACENTA DISORDER; PLACENTA INSUFFICIENCY; PREECLAMPSIA; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; SECOND TRIMESTER PREGNANCY; STROMA CELL; THIRD TRIMESTER PREGNANCY; ADULT; CASE CONTROL STUDY; CYTOLOGY; INTRAUTERINE GROWTH RETARDATION; METABOLISM; PLACENTA; PREGNANCY; REPRODUCTION;

ADULT; ANTIGENS, CD15; ANTIGENS, CD34; ANTIGENS, CD45; CASE-CONTROL STUDIES; DIABETES, GESTATIONAL; ENDOTHELIAL CELLS; FEMALE; FETAL GROWTH RETARDATION; FUCOSYLTRANSFERASES; GESTATIONAL AGE; HELLP SYNDROME; HUMANS; IMMUNOHISTOCHEMISTRY; PLACENTA; PLACENTATION; PRE-ECLAMPSIA; PREGNANCY;

EID: 84922462388     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2014.06.022     Document Type: Article

References (32)

1. Benirschke K, Kaufmann P, Baergen R. Pathology of the human placenta. 5th ed, New York: Springer; 2006.
2. Vogel M. Pathologie der Plazenta: Spätschwangerschaft und fetoplazentare Einheit. In: Klöppel G, Kreipe H, Remmele W, editors. Pathologie,. Heidelberg: Springer-Verlag; 2013. p. 519-39.
3. Stallmach T, Hebisch G. Rescue by birth: defective placental maturation and late fetal mortality obstetrics. Gynecology 2001;4:505-9.
4. Roescher AM, Timmer A, Hitzert MM, et al. Placental pathology and neurological morbidity in preterm infants during first two weeks after birth. Early Hum Dev 2014;1:21-5.
5. Vogel M. Atlas der morphologischen Plazentadiagnostik. 2nd ed, Heidelberg: Springer-Verlag; 1996.
6. Seidmann L, Suhan T, Unger R, Gerein V, Kirkpatrick CJ. Imbalance of expression of bFGF and PK1 is associated with defective maturation and antenatal placental insufficiency. Eur J Obstet Gynecol Reprod Biol 2013;170:352-7.
7. Wadsack C, Desoye G, Hiden U. The feto-placental endothelium in pregnancy pathologies. Wien Med Wochenshr 2012;162:220-4.
8. Gekas C, Dieterlen-Lievre F, Orkin SH, Mikkola HK. The placenta is a niche for hematopoietic stem cells. Dev Cell 2005;8:365-75. 2005.
9. Rhodes KE, Gekas C, Wang Y, et al. The emergence of hematopoietic stem cells is initiated in the placenta vasculature in the absence of circulation. Cell Stem Cell 2008;2:252-63.
10. Robin C, Bollerot K, Mendes S, et al. Human placenta is potent hematopoietic niche containing hematopoietic stem and proginetor cells throughout development. Cell Stem Cell 2009;5:386-95.
11. Challier JC, Galtier M, Cortez A, Bintein T, Rabreau M, Uzan S. Immunocytological evidence for hematopoiesis in the early human placenta. Placenta 2005;26:282-8.
12. Samokhvalov IM. Deconvoluting the ontogeny of the hematopoietic stem cells. Cell Mol Life Sci 2014;71:957-78.
13. Stocks SC, Kerr MA. Stimulation of neutrophil adhesion by antibodies recognizing CD15 (Le(X)) and CD15-expressing carcinoembryonic antigen-related glycoprotein NCA-160. Biochem J 1992;288:23-7.
14. Fox N, Damjanov I, Knowles BB, Solter D. Immunohistochemical localization of the mouse stage-specific embryonic antigen 1 in human tissues and tumors. Cancer Res 1983;43:669-78.
15. Hounsell EF, Gooi HC, Feizi T. The monoclonal antibody anti-SSEA-1 discriminates between fucosylated type 1 and type 2 blood group chains. FEBS Lett 1981;131:279-82.
16. Fox N, Damjanov I, Martinez-Hernandez A, Knowles BB, Solter D. Immunohistochemical localization of the early embryonic antigen (SSEA-1) in postimplantation mouse embryos and fetal and adult tissues. Dev Biol 1981;83:391-8.
17. Solter D, Knowles BB. Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proc Natl Acad Sci USA 1978;75:5565-9.
18. Capela A, Temple S. LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron 2002;35:865-75.
19. Imura T, Nakano I, Kornblum HI, Sofroniew MV. Phenotypic and functional heterogeneity of GFAP-expressing cells in vitro: differential expression of LeX/ CD15 by GFAP-expressing multipotent neural stem cells and non-neurogenic astrocytes. Glia 2006;53:277-93.
20. Masat T, Feliu E, Villamor N, et al. Immunophenotypic and ultrastructural study in peripheral blood neutrophil granulocytes following bone marrow transplantation. Br J Haematol 1997;98:299-307.
21. Nakayama F, Nishihara S, Iwasaki H, et al. CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX, but in promyelocytesand monocytes by alpha 1,3-fucosyltransferase IV. J Biol Chem2001;276:16100-06.
22. Thomas ML. The leukocyte common antigen family. Annu Rev Immunol 1989;7:339-69.
23. Choi KD, Vodyanik M, Slukvin II. Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells. Nat Protoc 2011;6:296-313.
24. Mathew TM. Fetoplacentla angiogenesis during gestation is biphasic, longitudinal and occurs by proliferation and remodeling of vascular endothelial cells. Placenta 2002;10:742-50.
25. Marshall CJ, Thrasher AJ. The embryonic origins of human haematopoiesis. Br J Haematol 2001;112:838-50.
26. Ottersbach K, Dzierzack E. The placenta as a haematopoietic organ. Int J Dev Biol 2010;54:1099-106.
27. Mei-Dan E, Fainaru O, Hantisteanu S, Shavit T, Ellenbogen A, Hallak M. Proangiogenic immature myeloid cells populate the human placenta and their presence correlates with placental and birth weight. Am J Obstet Gynecol 2012;207:141-5.
28. Bárcena A, Kapidzic M, Muench MO, et al. The human placenta is a hematopoietic organ during the embryonic and fetal periods of development. Dev Biol 2009;327(1):24-33.
29. Martinez-Agosto JA, Mikkola HK, Hartenstein V, Banerjee U. The hematopoietic stem cell and its niche: a comparative view. Genes Dev 2007;21: 3044-60.
30. North PE, Waner M, Mizeracki A, et al. A unique microvascular phenotype shared by juvenile hemangiomas and human placenta. Arch Dermatol 2001;137:559-70.
31. Itinteang T, Tan ST, Brasch H, Day DJ. Haemogenic endothelium in infantile haemangioma. J Clin Pathol 2010;63:982-6.
32. Barnes CM, Huang S, Kaipainen A, et al. Evidence by molecular profiling for a placental origin of infantile hemangioma. Proc Natl Acad Sci USA 2005;102: 19097-102.