Tumor location and IDH1 mutation may predict intraoperative seizures during awake craniotomy

Journal of Neurosurgery

Volumn 121, Issue 5, 2014, Pages 1133-1138

  Gonen, Tal ^a,b,d   Grossman, Rachel ^a   Sitt, Razi ^a   Nossek, Erez ^a   Yanaki, Raneen ^a   Cagnano, Emanuela ^a   Korn, Akiva ^a   Hayat, Daniel ^c   Ram, Zvi ^a  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b Wohl Institute for Advanced Imaging   (Israel)

^c Department of Anesthesia and Intensive Care ^*  (Hong Kong)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

Awake craniotomy; Brain tumors; Isocitrate dehydrogenase 1 mutation; Oncology; Seizures; Supplementary motor area

Indexed keywords

CARBAMAZEPINE; ISOCITRATE DEHYDROGENASE 1; PHENYTOIN; VALPROIC ACID; IDH1 PROTEIN, HUMAN; ISOCITRATE DEHYDROGENASE;

ADULT; ANTICONVULSANT THERAPY; ARTICLE; BRAIN TUMOR; CANCER SURGERY; CRANIOTOMY; FEMALE; FRONTAL LOBE; GENE MUTATION; HUMAN; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MIDDLE AGED; OUTCOME ASSESSMENT; PARIETAL LOBE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEIZURE; SUPPLEMENTARY MOTOR AREA; TEMPORAL LOBE; AGED; BRAIN NEOPLASMS; ELECTROSTIMULATION; GENETICS; INTRAOPERATIVE COMPLICATIONS; MOTOR CORTEX; MUTATION; NEUROSURGERY; PATHOLOGY; PREDICTIVE VALUE; SEIZURES; TREATMENT OUTCOME;

ADULT; AGED; BRAIN NEOPLASMS; CRANIOTOMY; ELECTRIC STIMULATION; FEMALE; HUMANS; INTRAOPERATIVE COMPLICATIONS; ISOCITRATE DEHYDROGENASE; MALE; MIDDLE AGED; MOTOR CORTEX; MUTATION; NEUROSURGICAL PROCEDURES; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SEIZURES; TREATMENT OUTCOME;

EID: 84922391529     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2014.7.JNS132657     Document Type: Article

References (25)

1. Blanshard HJ, Chung F, Manninen PH, Taylor MD, Bernstein M: Awake craniotomy for removal of intracranial tumor: considerations for early discharge. Anesth Analg 92:89-94, 2001
2. Bulsara KR, Johnson J, Villavicencio AT: Improvements in brain tumor surgery: the modern history of awake craniotomies. Neurosurg Focus 18(4):E5, 2005
3. Capper D, Weissert S, Balss J, Habel A, Meyer J, Jäger D, et al: Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors. Brain Pathol 20:245-254, 2010
4. Chang EF, Potts MB, Keles GE, Lamborn KR, Chang SM, Barbaro NM, et al: Seizure characteristics and control following resection in 332 patients with low-grade gliomas. J Neurosurg 108:227-235, 2008
5. Cordella R, Acerbi F, Marras CE, Carozzi C, Vailati D, Saini M, et al: Risk of seizures during intraoperative electrocortical stimulation of brain motor areas: a retrospective study on 50 patients. Neurol Sci 34:63-70, 2013
6. De Benedictis A, Moritz-Gasser S, Duffau H: Awake mapping optimizes the extent of resection for low-grade gliomas in eloquent areas. Neurosurgery 66:1074-1084, 2010
7. De Witt Hamer PC, Robles SG, Zwinderman AH, Duffau H, Berger MS: Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis. J Clin Oncol 30:2559-2565, 2012
8. DeAngelis LM: Brain tumors. N Engl J Med 344:114-123, 2001
9. Grossman R, Nossek E, Sitt R, Hayat D, Shahar T, Barzilai O, et al: Outcome of elderly patients undergoing awake-craniotomy for tumor resection. Ann Surg Oncol 20:1722-1728, 2013
10. Kleihues P, Burger PC, Scheithauer BW: The new WHO classification of brain tumours. Brain Pathol 3:255-268, 1993
11. Kölker S, Pawlak V, Ahlemeyer B, Okun JG, Hörster F, Mayatepek E, et al: NMDA receptor activation and respiratory chain complex V inhibition contribute to neurodegeneration in d-2-hydroxyglutaric aciduria. Eur J Neurosci 16:21-28, 2002
12. Labussière M, Idbaih A, Wang XW, Marie Y, Boisselier B, Falet C, et al: All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2. Neurology 74:1886-1890, 2010
13. Lee JW, Wen PY, Hurwitz S, Black P, Kesari S, Drappatz J, et al: Morphological characteristics of brain tumors causing seizures. Arch Neurol 67:336-342, 2010
14. Liigant A, Haldre S, Oun A, Linnamägi U, Saar A, Asser T, et al: Seizure disorders in patients with brain tumors. Eur Neurol 45:46-51, 2001
15. Nossek E, Matot I, Shahar T, Barzilai O, Rapoport Y, Gonen T, et al: Failed awake craniotomy: a retrospective analysis in 424 patients undergoing craniotomy for brain tumor. Clinical article. J Neurosurg 118:243-249, 2013
16. Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, et al: An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-1812, 2008
17. Rosenberg K, Nossek E, Liebling R, Fried I, Shapira-Lichter I, Hendler T, et al: Prediction of neurological deficits and recovery after surgery in the supplementary motor area: a prospective study in 26 patients. Clinical article. J Neurosurg 113:1152-1163, 2010
18. Sacko O, Lauwers-Cances V, Brauge D, Sesay M, Brenner A, Roux FE: Awake craniotomy vs surgery under general anesthesia for resection of supratentorial lesions. Neurosurgery 68:1192-1199, 2011
19. Sanai N, Chang S, Berger MS: Low-grade gliomas in adults. A review. J Neurosurg 115:948-965, 2011
20. Serletis D, Bernstein M: Prospective study of awake craniotomy used routinely and nonselectively for supratentorial tumors. J Neurosurg 107:1-6, 2007
21. Stockhammer F, Misch M, Helms HJ, Lengler U, Prall F, von Deimling A, et al: IDH1/2 mutations in WHO grade II astrocytomas associated with localization and seizure as the initial symptom. Seizure 21:194-197, 2012
22. Stockhammer F, von Deimling A, van Landeghem FK: Decreased expression of the active subunit of the cystine/glutamate antiporter xCT is associated with loss of heterozygosity of 1p in oligodendroglial tumours WHO grade II. Histopathology 54:241-247, 2009
23. Szelényi A, Bello L, Duffau H, Fava E, Feigl GC, Galanda M, et al: Intraoperative electrical stimulation in awake craniotomy: methodological aspects of current practice. Neurosurg Focus 28(2):E7, 2010
24. van Breemen MS, Wilms EB, Vecht CJ: Epilepsy in patients with brain tumours: epidemiology, mechanisms, and management. Lancet Neurol 6:421-430, 2007
25. Zilles K, Schlaug G, Matelli M, Luppino G, Schleicher A, Qü M, et al: Mapping of human and macaque sensorimotor areas by integrating architectonic, transmitter receptor, MRI and PET data. J Anat 187:515-537, 1995