Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease

Brain

Volumn 138, Issue 2, 2015, Pages 440-455

  Richetin, Kevin ^a   Leclerc, Clémence ^a,b   Toni, Nicolas ^c   Gallopin, Thierry ^b   Pech, Stéphane ^a   Roybon, Laurent ^d   Rampon, Claire ^a  

^a Université Paul Sabatier   (France)

^b Brain Plasticity Unit   (France)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

^d LUND UNIVERSITY   (Sweden)

Author keywords

Adult neurogenesis; Alzheimer's disease; Hippocampus; Memory; Neurod1

Indexed keywords

ALZHEIMER DISEASE; AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL MATURATION; CHROMOSOME PAIRING; DENDRITIC SPINE; FEMALE; GENE; GENETIC MANIPULATION; HIPPOCAMPUS; IN VIVO STUDY; MEMORY; MOUSE; NEURAL STEM CELL; NEUROD2 GENE; NEUROGENIC DIFFERENTIATION FACTOR GENE; NEUROGENIN 2 GENE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; COGNITIVE DEFECT; CYTOLOGY; DENTATE GYRUS; GENE TRANSFER; GENE VECTOR; GENETICS; MEMORY DISORDERS; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PHYSIOLOGY; PSYCHOLOGY; TRANSPLANTATION;

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; NERVE PROTEIN; NEUROD1 PROTEIN, MOUSE; NEUROD2 PROTEIN, MOUSE; NEUROG2 PROTEIN, MOUSE; NEUROPEPTIDE;

ALZHEIMER DISEASE; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; COGNITION DISORDERS; DENTATE GYRUS; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HIPPOCAMPUS; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NEUROGENESIS; NEURONS; NEUROPEPTIDES;

EID: 84922379340     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awu354     Document Type: Article

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