Structural analysis of the complex between Penta-Ef-Hand Alg-2 protein and sec31a peptide reveals a novel target recognition mechanism of Alg-2

International Journal of Molecular Sciences

Volumn 16, Issue 2, 2015, Pages 3677-3699

  Takeshi, Takahashi ^a   Kojima, Kyosuke ^a   Zhang, Wei ^a   Sasaki, Kanae ^a   Ito, Masaru ^a   Suzuki, Hironori ^b,c   Kawasaki, Masato ^b   Wakatsuki, Soichi ^b,d   Takahara, Terunao ^a   Shibata, Hideki ^a   Maki, Masatoshi ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b INSTITUTE OF MATERIALS STRUCTURE SCIENCE   (Japan)

^c UNIVERSITY OF CANTERBURY   (New Zealand)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adaptor protein; Calcium binding protein; COPII; Crystal structure; EF hand; Motif; Protein protein interaction

Indexed keywords

ADAPTOR PROTEIN; ALIX PEPTIDE; CALCIUM BINDING PROTEIN; COAT PROTEIN COMPLEX II; GLUTATHIONE TRANSFERASE ALPHA; OLIGONUCLEOTIDE; PENTA EF HAND PROTEIN ALG 2; PROTEIN; RECOMBINANT PROTEIN; SEC31A PEPTIDE; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CELL CYCLE PROTEIN; ESCRT PROTEIN; PDCD6 PROTEIN, HUMAN; PDCD6IP PROTEIN, HUMAN; PEPTIDE; PROTEIN BINDING; SEC31A PROTEIN, HUMAN; VESICULAR TRANSPORT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CHEMICAL ANALYSIS; CONTROLLED STUDY; CRYSTALLIZATION; DNA TRANSFECTION; ESCHERICHIA COLI; FAR WESTERN BLOTTING; GENETIC ANALYSIS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MUTAGENESIS; NONHUMAN; PLASMID; PROTEIN INTERACTION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DNA MUTATIONAL ANALYSIS; GENETICS; HEK293 CELL LINE; METABOLISM; X RAY CRYSTALLOGRAPHY;

MAMMALIA;

AMINO ACID SUBSTITUTION; APOPTOSIS REGULATORY PROTEINS; BINDING SITES; CALCIUM-BINDING PROTEINS; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; DNA MUTATIONAL ANALYSIS; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; VESICULAR TRANSPORT PROTEINS;

EID: 84922367951     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms16023677     Document Type: Article

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