Targeting of acute myeloid leukemia in vitro and in vivo with an anti-CD123 mAb engineered for optimal ADCC

Leukemia

Volumn 28, Issue 11, 2014, Pages 2213-2221

  Busfield, S J ^a   Biondo, M ^a   Wong, M ^a   Ramshaw, H S ^a   Lee, E M ^a   Ghosh, S ^a   Braley, H ^a   Panousis, C ^a   Roberts, A W ^a   He, S Z ^a   Thomas, D ^a   Fabri, L ^a   Vairo, G ^a   Lock, R B ^a   Lopez, A F ^a   Nash, A D ^a  

^a CSL LIMITED   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD123 ANTIGEN; FC RECEPTOR; FCGR3B PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; IL3RA PROTEIN, HUMAN; MONOCLONAL ANTIBODY;

ANIMAL; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; CANCER TRANSPLANTATION; DISEASE MODEL; DRUG SCREENING; FEMALE; HUMAN; IMMUNOLOGY; LEUKEMIA, ERYTHROBLASTIC, ACUTE; LEUKEMIA, MYELOID, ACUTE; MACACA FASCICULARIS; NATURAL KILLER CELL; NONOBESE DIABETIC MOUSE; PROTEIN ENGINEERING; SCID MOUSE;

ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; DISEASE MODELS, ANIMAL; FEMALE; GPI-LINKED PROTEINS; HUMANS; INTERLEUKIN-3 RECEPTOR ALPHA SUBUNIT; KILLER CELLS, NATURAL; LEUKEMIA, ERYTHROBLASTIC, ACUTE; LEUKEMIA, MYELOID, ACUTE; MACACA FASCICULARIS; MICE, INBRED NOD; MICE, SCID; NEOPLASM TRANSPLANTATION; PROTEIN ENGINEERING; RECEPTORS, IGG; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84922283792     PISSN: None     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2014.128     Document Type: Article

References (0)