Ipilimumab-induced hypophysitis: Early Australian experience

Medical Journal of Australia

Volumn 201, Issue 4, 2014, Pages 198-199

  De Sousa, Sunita M C ^a   Long, Georgina V ^b   Tonks, Katherine T ^c  

^a ST VINCENT S HOSPITAL   (Australia)

^b MELANOMA INSTITUTE AUSTRALIA   (Australia)

^c GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DEXAMETHASONE; FOLLITROPIN; HYDROCORTISONE; IPILIMUMAB; LIOTHYRONINE; PREDNISOLONE; TESTOSTERONE; THYROTROPIN; THYROXINE; ANTINEOPLASTIC AGENT; GLUCOCORTICOID; MONOCLONAL ANTIBODY;

ADULT; ANDROGEN THERAPY; ANOREXIA; ASTHENIA; CASE REPORT; CELL PROLIFERATION; DIZZINESS; DRUG DOSE REDUCTION; DRUG MEGADOSE; FATIGUE; HEADACHE; HUMAN; HYPOGONADISM; HYPOPHYSITIS; INSULIN TOLERANCE TEST; LETTER; LUMBAR PUNCTURE; MALE; METASTATIC MELANOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; T LYMPHOCYTE ACTIVATION; TUMOR GROWTH; VOMITING; AUSTRALIA; CHEMICALLY INDUCED; DISEASE COURSE; HYPOPITUITARISM; IMMUNOLOGY; MELANOMA; MIDDLE AGED; PATHOLOGY; SECONDARY; SKIN NEOPLASMS;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; AUSTRALIA; DISEASE PROGRESSION; GLUCOCORTICOIDS; HUMANS; HYPOPITUITARISM; MALE; MELANOMA; MIDDLE AGED; PREDNISOLONE; SKIN NEOPLASMS;

EID: 84922251051     PISSN: 0025729X     EISSN: 13265377     Source Type: Journal    
DOI: 10.5694/mja14.00803     Document Type: Letter

References (5)

1. Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma.N Engl J Med2010; 363: 711-723.
2. Ryder M, Callahan M, Postow MA, et al. Endocrine-related adverse events following ipilimumab in patients with advanced melanoma: a comprehensive retrospective review from a single institution.Endocr Relat Cancer2014; 21: 371-381.
3. Gutenberg A, Larsen J, Lupi I, et al. A radiologic score to distinguish autoimmune hypophysitis from nonsecreting pituitary adenoma preoperatively.Am J Neuroradiol2009; 30: 1766-1772.
4. Torino F, Barnabei A, De Vecchis L, et al. Hypophysitis induced by monoclonal antibodies to cytotoxic T lymphocyte antigen 4: challenges from a new cause of a rare disease.Oncologist2012; 17: 525-535.
5. Blansfield JA, Beck KE, Tran K, et al. Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer.J Immunother2005; 28: 593-598