Functional G-protein-coupled receptor 35 is expressed by neurons in the CA1 field of the hippocampus

Biochemical Pharmacology

Volumn 93, Issue 4, 2015, Pages 506-518

  Alkondon, Manickavasagom ^a   Pereira, Edna F R ^a   Todd, Spencer W ^a   Randall, William R ^a   Lane, Malcolm V ^a   Albuquerque, Edson X ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Action potential; Amlexanox; Dicumarol; ML145; Sildenafil; Stratum radiatum interneuron; Zaprinast

Indexed keywords

DICOUMAROL; EMBONIC ACID; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 35; SILDENAFIL; UNCLASSIFIED DRUG; ZAPRINAST; GPR35 PROTEIN, RAT;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIPPOCAMPAL CA1 REGION; IMMUNOHISTOCHEMISTRY; INTERNEURON; MALE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STRATUM ORIENS; STRATUM RADIATUM; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; HEK293 CELL LINE; HUMAN; METABOLISM; NEWBORN; ORGAN CULTURE TECHNIQUE; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; CA1 REGION, HIPPOCAMPAL; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MALE; NEURONS; ORGAN CULTURE TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84922140794     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.12.009     Document Type: Article

References (36)

1. B.F. O'Dowd, T. Nguyen, A. Marchese, R. Cheng, K.R. Lynch, and H.H. Heng Discovery of three novel G-protein-coupled receptor genes Genomics 47 1998 310 313
2. J. Wang, N. Simonavicius, X. Wu, G. Swaminath, J. Reagan, and H. Tian Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35 J Biol Chem 281 2006 22021 22028
3. E.X. Albuquerque, E.F.R. Pereira, M. Alkondon, and S.W. Rogers Mammalian nicotinic acetylcholine receptors: from structure to function Physiol Rev 89 2009 73 120
4. α13 and β-arrestin-2 Br J Pharmacol 162 2011 733 748
5. J. Guo, D.J. Williams, H.L. Puhl III, and S.R. Ikeda Inhibition of N-type calcium channels by activation of GPR35, an orphan receptor, heterologously expressed in rat sympathetic neurons J Pharmacol Exp Ther 324 2008 342 351
6. L. Vecsei, L. Szalardy, F. Fulop, and J. Toldi Kynurenines in the CNS: recent advances and new questions Nature Rev 12 2013 64 82
7. Y. Taniguchi, H. Tonai-Kachi, and K. Shinjo Zaprinast, a well-known cyclic guanosine monophosphate-specific phosphodiesterase inhibitor, is an agonist for GPR35 FEBS Lett 580 2006 5003 5008
8. H. Ohshiro, H. Tonai-Kachi, and K. Ichikawa GPR35 is a functional receptor in rat dorsal root ganglion neurons Biochem Biophy Res Com 365 2008 344 348
9. A.E. MacKenzie, J.E. Lappin, D.L. Taylor, S.A. Nicklin, and G. Milligan GPR35 as a novel therapeutic target Front Endocrinol 2 2011 1 10
10. A.E. MacKenzie, G. Caltabiano, T.C. Kent, L. Jenkins, J.E. McCallum, and B.D. Hudson The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35 Mol Pharmacol 85 2014 91 104
11. P. Zhao, H. Sharir, A. Kapur, A. Cowan, E.B. Geller, and M.W.H. Adler Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and beta-arrestin2 with antinociceptive activity Mol Pharmacol 78 2010 560 568
12. S. Heynen-Genel, R. Dahl, S. Shi, M. Sauer, S. Hariharan, and E. Sergienko Antagonists for the Orphan Receptor GPR35. Probe Reports from the NIH Molecular Libraries Program [Internet] 2010 National Center for Biotechnology Information Bethesda, MD
13. L. Jenkins, N. Harries, J.E. Lappin, A.E. MacKenzie, Z. Neetoo-Isseljee, and C. Southern Antagonists of GPR35 display high species ortholog selectivity and varying modes of action J Pharmacol Exp Ther 343 2012 683 695
14. G. Paxinos, and C. Watson The rat brain in stereotaxic coordinates Second Edition 1986 Academic Press Amsterdam
15. J. Bordeaux, A.W. Welsh, S. Agarwal, E. Killiam, M.T. Baquero, and J.A. Hanna Biotechniques 48 2010 197 209
16. M. Alkondon, E.F. Pereira, and E.X. Albuquerque Endogenous activation of nAChRs and NMDA receptors contribute to the excitability of CA1 stratum radiatum interneurons in rat hippocampal slices: effects of kynurenic acid Biochem Pharmacol 82 2011 842 851
17. A.E. Shrimpton, B.R. Braddock, L.L. Thompson, C.K. Stein, and J.J. Hoo Molecular delineation of deletions on 2q37.3 in three cases with an Albright hereditary osteodystrophy-like phenotype Clin Genet 66 2004 537 544
18. 2+ transients and contributes to the kynurenic acid-dependent reduction of synaptic activity at CA3-CA1-synapses PLoS ONE 8 11 2013 e82180
19. α13 Biochem J 432 2010 451 459
20. Y. Yang, J.Y. Lu, X. Wu, S. Summer, J. Whoriskey, and C. Saris G-protein-coupled receptor 35 is s target of the asthma drugs cromolyn disodium and nedocromil sodium Pharmacology 86 2010 1 5
21. Z. Neetoo-Isseljee, A.E. MacKenzie, C. Southern, J. Jerman, E.G. McIver, and N. Harries High-throughput identification and characterization of novel, species-selective GPR35 agonists J Pharmacol Exp Ther 344 2013 568 578
22. M. Funke, D. Thimm, A.C. Schiedel, and C.E. Muller 8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35 J Med Chem 56 2013 5182 5197
23. H.Y. Hu, J.K. Horton, M.R. Gryk, R. Prasad, J.M. Naron, and D.-A. Sun Identification of small molecule synthetic inhibitors of DNA polymerase β by NMR chemical shift mapping J Biol Chem 279 2004 39736 39744
24. I.V. Turko, S.A. Ballard, S.H. Francis, and J.D. Corbin Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds Mol Pharmacol 56 1999 124 130
25. E.O. de Aspuru, and A.M.L. Zaton Effect of the antiallergic drug disodium cromoglycate on phosphodiesterase activity J Enzyme Inhib Med Chem 10 1996 135 139
26. h) to membrane potential and GABA release in hippocampal interneurons J Neurophysiol 86 2001 261 268
27. h J Neurophysiol 101 2009 67 83
28. S.K. Halder, H. Matsunaga, and H. Ueda Neuron-specific non-classical release of prothymosin alpha: a novel neuroprotective damage-associated molecular patterns J Neurochem 123 2012 262 275
29. V.-P. Ronkainen, T. Tuomainen, J. Huusko, S. Laidinen, M. Malinen, and J.J. Palvimo Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression in an early marker of progressive cardiac remodeling Cardiovas Res 101 2014 69 77
30. E.X. Albuquerque, and R. Schwarcz Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges Biochem Pharmacol 85 2013 1027 1032
31. S. Erhardt, K. Blennow, C. Nordin, E. Skogh, L.H. Lindström, and G. Engberg Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia Neurosci Lett 313 2001 96 98
32. K.R. Linderholm, E. Skogh, S.K. Olsson, M.L. Dahl, M. Holtze, and G. Engberg Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia Schizophr Bull 38 2012 426 432
33. R. Schwarcz, A. Rassoulpour, H.Q. Wu, D. Medoff, C.A. Tamminga, and R.C. Roberts Increased cortical kynurenate content in schizophrenia Biol Psychiatry 50 2001 521 530
34. R. Freedman, C.E. Adams, and S. Leonard The α7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia J Chem Neuroanat 20 2000 299 306
35. R. Nguyen, M.D. Morrissey, V. Mahadevan, J.D. Cajanding, M.A. Woodin, and J.S. Yeomans Parvalbumin and GAD65 interneuron inhibition in the ventral hippocampus induces distinct behavioral deficits relevant to schizophrenia J Neurosci 34 2014 14948 14960
36. M.C. Barth, N. Ahluwalia, T.J.T. Anderson, G.J. Hardy, S. Sinha, and J.A. Alvarez-Cardona Kynurenic acid triggers firm arrest of leukocytes to vascular endothelium under flow conditions J Biol Chem 284 2009 19189 19195