Potential role of fluctuations in the composition of renal tubular fluid through the nephron in the initiation of Randall’s plugs and calcium oxalate crystalluria in a computer model of renal function

Urolithiasis

Volumn 43, Issue 1, 2014, Pages 93-107

  Robertson, W G ^a,b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b NONE   (United Kingdom)

Author keywords

Calcium; Crystallisation; Oxalate; Phosphate; Randall s plugs; Relative supersaturation

Indexed keywords

CALCIUM; CALCIUM OXALATE; CALCIUM PHOSPHATE; OXALIC ACID; PHOSPHATE;

CALCIUM BLOOD LEVEL; COMPUTER MODEL; CONTROLLED STUDY; CRYSTAL; CRYSTALLURIA; HENLE LOOP; HUMAN; HYDRODYNAMICS; KIDNEY FUNCTION; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE EXCRETION; LIQUID; NEPHROLITHIASIS; NEPHRON; PHOSPHATE BLOOD LEVEL; PREDICTION; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; REVIEW; URINE; BIOLOGICAL MODEL; BODY FLUID; CALCINOSIS; CHEMISTRY; CRYSTALLIZATION; KIDNEY; KIDNEY DISEASES; KIDNEY MEDULLA; METABOLISM; PHYSIOLOGY;

BODY FLUIDS; CALCINOSIS; CALCIUM OXALATE; CRYSTALLIZATION; KIDNEY; KIDNEY DISEASES; KIDNEY MEDULLA; KIDNEY TUBULES; MODELS, BIOLOGICAL; NEPHRONS;

EID: 84922103667     PISSN: 21947228     EISSN: 21947236     Source Type: Journal    
DOI: 10.1007/s00240-014-0737-1     Document Type: Review

References (46)

1. Boyce WH, King JS Jr (1963) Present concepts concerning the origin of matrix and stones. Ann NY Acad Sci 104:563–578
2. Keutel HJ, King JS Jr, Boyce WH (1964) Further studies of uromucoid in normal and stone urine. Urol Int 17:324–341
3. Howard JE, Thomas WC Jr, Mukai T, Johnston RA Jr, Pascoe BJ (1962) The calcification of cartilage by urine, and a suggestion for therapy in patients with certain kinds of calculi. Trans Assoc Am Physicians 75:301–306
4. Fleisch H, Bisaz S (1964) The inhibitory effect of pyrophosphate on calcium oxalate precipitation and its relation to urolithiasis. Experientia 15:276–277
5. Vermeulen CW, Lyon ES, Gill WB (1964) Artificial urinary concretions. Invest Urol 1:370–386
6. Robertson WG, Peacock M, Nordin BEC (1968) Activity products in stone-forming and non-stone-forming urine. Clin Sci 34:579–594
7. Kolbach AM, Afzal O, Sorokina E, Kleinman JG, Wesson JA (2012) Relative deficiency of acidic forms of osteopontin from stone former urine. Urol Res 40:447–454
8. Ryall RL (2008) The future of stone research: rummaging in the attic, Randall’s plaque, nanobacteria, and lessons from phylogeny. Urol Res 36:77–97
9. Finlayson B, Reid F (1978) The expectation of free and fixed particles in urinary stone disease. Invest Urol 15:442–448
10. Robertson WG, Peacock M, Nordin BEC (1969) Calcium crystalluria in recurrent renal stone-formers. Lancet 2:21–24
11. Kok DJ, Papapoulos SE, Bijvoet OLM (1990) Crystal agglomeration is a major element in calcium oxalate urinary stone formation. Kidney Int 37:51–56
12. Kumar S, Sigmon D, Miller T, Carpenter B, Khan S, Malhotra R, Scheid C, Menon M (1991) A new model of nephrolithiasis involving tubular dysfunction/injury. J Urol 146:1384–1389
13. Bigelow MW, Wiessner JH, Kleinman JG, Mandel NS (1998) Calcium oxalate crystal attachment to cultured kidney epithelial cell lines. J Urol 160:1528–1532
14. Verkoelen CF, van der Boom BG, Houtsmuller AB, Schröder FH, Romijn JC (1998) Increased calcium oxalate monohydrate crystal binding to injured tubular epithelial cells in culture. Am J Physiol 274:F958–F965
15. Scheid C, Koul H, Hill WA, Luber-Narod J, Jonassen J, Honeyman T, Kennington L, Kohli R, Hodapp J, Ayvazian P, Menon M (1996) Oxalate toxicity in LLC-PK1 cells: role of free radicals. Kidney Int 49:413–419
16. Lieske JC, Leonard R, Swift HS, Toback FG (1996) Adhesion of calcium oxalate monohydrate crystals to anionic sites of renal epithelial cells. Am J Physiol 270:F192–F199
17. Koul H, Kennington L, Honeyman T, Jonassen J, Menon M, Scheid C (1996) Activation of c-myc gene mediates the mitogenic effects of oxalate in LLC-PK1 cells, a line of renal epithelial cells. Kidney Int 50:1525–1530
18. Kok DJ, Khan SR (1994) Calcium oxalate nephrolithiasis, a free or fixed particle disease. Kidney Int 46:847–854
19. Robertson WG (2004) Kidney models of calcium oxalate stone-formation. Nephron Physiol 98:21–30
20. Randall A (1936) An hypothesis for the origin of renal calculus. N Engl J Med 214:234–237
21. Randall A (1937) The origin and growth of renal calculi. Ann Surg 105:1009–1027
22. Cifuentes Delatte L, Minon-Cifuentes J, Medina JA (1985) Papillary stones: calcified renal tubules in Randall’s plaques. J Urol 133:490–494
23. Evan AP, Lingeman JE, Coe FL, Parks JH, Bledsoe SB, Shao Y, Sommer AJ, Paterson RF, Kuo RL, Grynpas M (2003) Randall’s plaque of patients with nephrolithiasis begins in basement membranes of thin Loops of Henle. J Clin Invest 111:607–616
24. Evan AP, Lingeman JE, Coe FL, Shao Y, Parks JH, Bledsoe SB, Phillips CL, Bonsib S, Worcester EM, Sommer AJ, Kim SC, Tinmouth WW, Grynpas M (2005) Crystal-associated nephropathy in patients with brushite nephrolithiasis. Kidney Int 67:576–591
25. Knight TF, Sansom SC, Senekjian HO, Weinman EJ (1981) Oxalate secretion in the rat proximal tubule. Am J Physiol 240:F295–F298
26. Holmes RP, Ambrosius WT, Assimos DG (2005) Dietary loads and renal oxalate handling. J Urol 174:943–947
27. Worcester EM, Evan AP, Coe FL, Lingeman JE, Krambeck A, Sommers A, Phillips CL, Milliner D (2013) A test of the hypothesis that oxalate secretion produces proximal tubule crystallization in primary hyperoxaluria type 1. Am J Physiol Renal Physiol 305:F1574–F1584
28. Robertson WG, Peacock M, Nordin BEC (1971) Calcium oxalate crystalluria and urine saturation in recurrent stone-formers. Clin Sci 40:365–374
29. Robertson WG (2012) Stone-formation in the Middle Eastern Gulf States—a review. Arab J Urol 10:265–272
30. Robertson WG (1969) Measurement of ionized calcium in biological fluids. Clin Chim Acta 24:149–157
31. Robertson WG (1969) Physicochemical aspects of renal stone-formation. Ph.D. Thesis, University of Leeds, UK
32. Hautmann RE (1993) The stomach: a new and powerful oxalate absorption site in man. J Urol 149:1401–1404
33. Chen Z, Ye Z, Zeng L, Yang W (2003) Clinical investigation on gastric oxalate absorption. Chin Med J (Engl) 116:1749–1751
34. Freel RW, Hatch M, Earnest DL, Goldner AM (1980) Oxalate transport across the isolated rat colon. A re-examination. Biochim Biophys Acta 600:838–843
35. Hatch M, Freel RW, Vaziri ND (1993) Characteristics of the transport of oxalate and other ions across rabbit proximal colon. Pflugers Arch 423:206–212
36. Tomson MB, Nancollas GH (1978) Mineralization kinetics: a constant composition approach. Science 200:1059–1060
37. Asplin JR, Mandel NS, Coe FL (1996) Evidence of calcium phosphate supersaturation in the Loop of Henle. Am J Physiol 270:F604–F613
38. Robertson WG, Nordin BEC (1969) Activity products in urine. In: Hodgkinson A, Nordin BEC (eds) Proceedings of the renal stone research symposium. Churchill, London, pp 221–232
39. Schulz E, Hengst E, Brundig P, Haerting R, Pirlich W, Günther H (1987) Disturbed urinary transport in the pelvi-calcyceal system in calcium oxalate stone patients. Urol Res 15:109–113
40. Graves FT (1982) An experimental study of the anatomy of the tubules of the human kidney and its relation to calculus formation. Br J Urol 54:569–574
41. Sengbusch R, Timmermann A (1957) Das Kristalline Calciumoxalat im menschlichen Harn und seine Beziehung zur Oxalatstein-Bildung. Urol Int 4:76–95
42. Tiselius HG (1999) Crystalluria in patients with calcium stone disease. J Urol 161:1432
43. Robertson WG (unpublished data)
44. Robertson WG, Peacock M, Marshall RW, Knowles F (1974) The effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) on calcium oxalate crystalluria in recurrent renal stone-formers. Clin Sci 47:13–22
45. Buckley CM, Hawthorne A, Colyer A, Stevenson AE (2011) Effect of dietary water intake on urinary output, specific gravity and relative supersaturation for calcium oxalate and struvite in the cat. Br J Nutr 106(Suppl 1):S128–S130
46. Tiselius HG (2013) The role of calcium phosphate in the development of Randall’s plaques. Urolithiasis 41:369–377