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Volumn 36, Issue 2, 2015, Pages 179-188

Association between ubiquitin carboxy-terminal hydrolase-L1 S18Y variant and risk of Parkinson’s disease: the impact of ethnicity and onset age

Author keywords

Meta analysis; Parkinson s disease; Polymorphism; UCHL1

Indexed keywords

UBIQUITIN CARBOXY TERMINAL HYDROLASE L1; UBIQUITIN THIOLESTERASE; UNCLASSIFIED DRUG; UCHL1 PROTEIN, HUMAN;

EID: 84922071307     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-014-1987-y     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 33644610520 scopus 로고    scopus 로고
    • The genetics of Parkinson disease: implications for neurological care
    • COI: 1:CAS:528:DC%2BD28Xis1yjsb8%3D, PID: 16932540
    • Klein C, Schlossmacher MG (2006) The genetics of Parkinson disease: implications for neurological care. Nat Clin Pract Neurol 2:136–146
    • (2006) Nat Clin Pract Neurol , vol.2 , pp. 136-146
    • Klein, C.1    Schlossmacher, M.G.2
  • 3
  • 4
    • 84879334553 scopus 로고    scopus 로고
    • Environmental-genetic interactions in the pathogenesis of Parkinson’s disease
    • PID: 23055790
    • Tsuboi Y (2012) Environmental-genetic interactions in the pathogenesis of Parkinson’s disease. Exp Neurobiol 21:123–128
    • (2012) Exp Neurobiol , vol.21 , pp. 123-128
    • Tsuboi, Y.1
  • 5
    • 84894075304 scopus 로고    scopus 로고
    • Genetic insights into sporadic Parkinson’s disease pathogenesis
    • COI: 1:CAS:528:DC%2BC2cXjtl2ks7Y%3D, PID: 24532982
    • Chai C, Lim KL (2013) Genetic insights into sporadic Parkinson’s disease pathogenesis. Curr Genomics 14:486–501
    • (2013) Curr Genomics , vol.14 , pp. 486-501
    • Chai, C.1    Lim, K.L.2
  • 6
    • 79959728747 scopus 로고    scopus 로고
    • Epidemiology and etiology of Parkinson’s disease: a review of the evidence
    • PID: 21626386
    • Wirdefeldt K, Adami HO, Cole P, Trichopoulos D, Mandel J (2011) Epidemiology and etiology of Parkinson’s disease: a review of the evidence. Eur J Epidemiol 26(Suppl 1):S1–S58
    • (2011) Eur J Epidemiol , vol.26 , pp. S1-S58
    • Wirdefeldt, K.1    Adami, H.O.2    Cole, P.3    Trichopoulos, D.4    Mandel, J.5
  • 7
    • 84862689309 scopus 로고    scopus 로고
    • The neuropathology of genetic Parkinson’s disease
    • COI: 1:CAS:528:DC%2BC38Xhs1GhtrbO, PID: 22451330
    • Poulopoulos M, Levy OA, Alcalay RN (2012) The neuropathology of genetic Parkinson’s disease. Mov Disord 27:831–842
    • (2012) Mov Disord , vol.27 , pp. 831-842
    • Poulopoulos, M.1    Levy, O.A.2    Alcalay, R.N.3
  • 8
    • 33644919942 scopus 로고    scopus 로고
    • Implications of genetics on the diagnosis and care of patients with Parkinson disease
    • PID: 16533959
    • Klein C (2006) Implications of genetics on the diagnosis and care of patients with Parkinson disease. Arch Neurol 63:328–334
    • (2006) Arch Neurol , vol.63 , pp. 328-334
    • Klein, C.1
  • 9
    • 73449149047 scopus 로고    scopus 로고
    • Gene therapy for neurological disorders: challenges and future prospects for the use of growth factors for the treatment of Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD1MXhsFGqtLfM, PID: 19860652
    • Manfredsson FP, Okun MS, Mandel RJ (2009) Gene therapy for neurological disorders: challenges and future prospects for the use of growth factors for the treatment of Parkinson’s disease. Curr Gene Ther 9:375–388
    • (2009) Curr Gene Ther , vol.9 , pp. 375-388
    • Manfredsson, F.P.1    Okun, M.S.2    Mandel, R.J.3
  • 10
    • 84879489900 scopus 로고    scopus 로고
    • Genetic variations of GAK in two Chinese Parkinson’s disease populations: a case-control study
    • COI: 1:CAS:528:DC%2BC3sXhtV2qtbrP, PID: 23826309
    • Tseng WE, Chen CM, Chen YC, Yi Z, Tan EK, Wu YR (2013) Genetic variations of GAK in two Chinese Parkinson’s disease populations: a case-control study. PLoS One 8:e67506
    • (2013) PLoS One , vol.8 , pp. e67506
    • Tseng, W.E.1    Chen, C.M.2    Chen, Y.C.3    Yi, Z.4    Tan, E.K.5    Wu, Y.R.6
  • 11
    • 84886092912 scopus 로고    scopus 로고
    • Fibroblast growth factor 20 polymorphism in sporadic Parkinson’s disease in Northern Han Chinese
    • COI: 1:CAS:528:DC%2BC3sXht1GgtrzI, PID: 23938014
    • Xu X, Wang N, Xu H, Xie A, Jiang H, Xie J (2013) Fibroblast growth factor 20 polymorphism in sporadic Parkinson’s disease in Northern Han Chinese. J Clin Neurosci 20:1588–1590
    • (2013) J Clin Neurosci , vol.20 , pp. 1588-1590
    • Xu, X.1    Wang, N.2    Xu, H.3    Xie, A.4    Jiang, H.5    Xie, J.6
  • 12
    • 84868205698 scopus 로고    scopus 로고
    • Genetic risk factors in Parkinson’s disease: single gene effects and interactions of genotypes
    • PID: 22878430
    • Gobel A, Macklin EA, Winkler S, Betensky RA, Klein C, Lohmann K et al (2012) Genetic risk factors in Parkinson’s disease: single gene effects and interactions of genotypes. J Neurol 259:2503–2505
    • (2012) J Neurol , vol.259 , pp. 2503-2505
    • Gobel, A.1    Macklin, E.A.2    Winkler, S.3    Betensky, R.A.4    Klein, C.5    Lohmann, K.6
  • 13
    • 84860470675 scopus 로고    scopus 로고
    • Mutation analysis of LRRK2, SCNA, UCHL1, HtrA2 and GIGYF2 genes in Chinese patients with autosomal dorminant Parkinson’s disease
    • COI: 1:CAS:528:DC%2BC38XmtFams78%3D, PID: 22503729
    • Tian JY, Guo JF, Wang L, Sun QY, Yao LY, Luo LZ et al (2012) Mutation analysis of LRRK2, SCNA, UCHL1, HtrA2 and GIGYF2 genes in Chinese patients with autosomal dorminant Parkinson’s disease. Neurosci Lett 516:207–211
    • (2012) Neurosci Lett , vol.516 , pp. 207-211
    • Tian, J.Y.1    Guo, J.F.2    Wang, L.3    Sun, Q.Y.4    Yao, L.Y.5    Luo, L.Z.6
  • 14
    • 0032190090 scopus 로고    scopus 로고
    • The ubiquitin pathway in Parkinson’s disease
    • COI: 1:CAS:528:DyaK1cXms1antLo%3D, PID: 9774100
    • Leroy E, Boyer R, Auburger G, Leube B, Ulm G, Mezey E et al (1998) The ubiquitin pathway in Parkinson’s disease. Nature 395:451–452
    • (1998) Nature , vol.395 , pp. 451-452
    • Leroy, E.1    Boyer, R.2    Auburger, G.3    Leube, B.4    Ulm, G.5    Mezey, E.6
  • 15
    • 0033525009 scopus 로고    scopus 로고
    • Low frequency of pathogenic mutations in the ubiquitin carboxy-terminal hydrolase gene in familial Parkinson’s disease
    • COI: 1:STN:280:DyaK1M3hvVSisw%3D%3D, PID: 10203348
    • Lincoln S, Vaughan J, Wood N, Baker M, Adamson J, Gwinn-Hardy K et al (1999) Low frequency of pathogenic mutations in the ubiquitin carboxy-terminal hydrolase gene in familial Parkinson’s disease. Neuroreport 10:427–429
    • (1999) Neuroreport , vol.10 , pp. 427-429
    • Lincoln, S.1    Vaughan, J.2    Wood, N.3    Baker, M.4    Adamson, J.5    Gwinn-Hardy, K.6
  • 16
    • 0033544368 scopus 로고    scopus 로고
    • Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson’s disease
    • COI: 1:CAS:528:DyaK1MXnvVKns70%3D, PID: 10563640
    • Maraganore DM, Farrer MJ, Hardy JA, Lincoln SJ, McDonnell SK, Rocca WA (1999) Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson’s disease. Neurology 53:1858–1860
    • (1999) Neurology , vol.53 , pp. 1858-1860
    • Maraganore, D.M.1    Farrer, M.J.2    Hardy, J.A.3    Lincoln, S.J.4    McDonnell, S.K.5    Rocca, W.A.6
  • 17
    • 77957661914 scopus 로고    scopus 로고
    • Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses
    • PID: 20652370
    • Stang A (2010) Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol 25:603–605
    • (2010) Eur J Epidemiol , vol.25 , pp. 603-605
    • Stang, A.1
  • 18
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • COI: 1:STN:280:DyaG1M%2FosVOhtQ%3D%3D, PID: 13655060
    • Mantel N, Haenszel W (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 22:719–748
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 19
    • 33845571913 scopus 로고    scopus 로고
    • Random-effects model for meta-analysis of clinical trials: an update
    • PID: 16807131
    • DerSimonian R, Kacker R (2007) Random-effects model for meta-analysis of clinical trials: an update. Contemp Clin Trials 28:105–114
    • (2007) Contemp Clin Trials , vol.28 , pp. 105-114
    • DerSimonian, R.1    Kacker, R.2
  • 20
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • PID: 12111919
    • Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539–1558
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 21
    • 0025066941 scopus 로고
    • More powerful procedures for multiple significance testing
    • COI: 1:STN:280:DyaK3M%2FhvFSgsA%3D%3D, PID: 2218183
    • Hochberg Y, Benjamini Y (1990) More powerful procedures for multiple significance testing. Stat Med 9(7):811–818
    • (1990) Stat Med , vol.9 , Issue.7 , pp. 811-818
    • Hochberg, Y.1    Benjamini, Y.2
  • 22
    • 84977804725 scopus 로고
    • A simple sequentially rejective bonferroni test procedure
    • Holm S (1979) A simple sequentially rejective bonferroni test procedure. Scand J Stat 6:65–70
    • (1979) Scand J Stat , vol.6 , pp. 65-70
    • Holm, S.1
  • 23
    • 0036135090 scopus 로고    scopus 로고
    • Association studies of multiple candidate genes for Parkinson’s disease using single nucleotide polymorphisms
    • COI: 1:CAS:528:DC%2BD38XmvVOgsA%3D%3D, PID: 11782995
    • Momose Y, Murata M, Kobayashi K, Tachikawa M, Nakabayashi Y, Kanazawa I et al (2002) Association studies of multiple candidate genes for Parkinson’s disease using single nucleotide polymorphisms. Ann Neurol 51:133–136
    • (2002) Ann Neurol , vol.51 , pp. 133-136
    • Momose, Y.1    Murata, M.2    Kobayashi, K.3    Tachikawa, M.4    Nakabayashi, Y.5    Kanazawa, I.6
  • 24
    • 0142125347 scopus 로고    scopus 로고
    • Toward identification of susceptibility genes for sporadic Parkinson’s disease
    • PID: 14579123
    • Toda T, Momose Y, Murata M, Tamiya G, Yamamoto M, Hattori N et al (2003) Toward identification of susceptibility genes for sporadic Parkinson’s disease. J Neurol 250(Suppl 3):III40–III43
    • (2003) J Neurol , vol.250 , pp. III40-III43
    • Toda, T.1    Momose, Y.2    Murata, M.3    Tamiya, G.4    Yamamoto, M.5    Hattori, N.6
  • 25
    • 0033947504 scopus 로고    scopus 로고
    • Association between a polymorphism of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) gene and sporadic Parkinson’s disease
    • PID: 10900392
    • Zhang J, Hattori N, Leroy E, Morris HR, Kubo S, Kobayashi T et al (2000) Association between a polymorphism of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) gene and sporadic Parkinson’s disease. Parkinsonism Relat Disord 6:195–197
    • (2000) Parkinsonism Relat Disord , vol.6 , pp. 195-197
    • Zhang, J.1    Hattori, N.2    Leroy, E.3    Morris, H.R.4    Kubo, S.5    Kobayashi, T.6
  • 26
    • 0035881339 scopus 로고    scopus 로고
    • A polymorphic variation of serine to tyrosine at codon 18 in the ubiquitin C-terminal hydrolase-L1 gene is associated with a reduced risk of sporadic Parkinson’s disease in a Japanese population
    • COI: 1:CAS:528:DC%2BD3MXmsFelsro%3D, PID: 11535241
    • Satoh J, Kuroda Y (2001) A polymorphic variation of serine to tyrosine at codon 18 in the ubiquitin C-terminal hydrolase-L1 gene is associated with a reduced risk of sporadic Parkinson’s disease in a Japanese population. J Neurol Sci 189:113–117
    • (2001) J Neurol Sci , vol.189 , pp. 113-117
    • Satoh, J.1    Kuroda, Y.2
  • 27
    • 54249162651 scopus 로고    scopus 로고
    • Association of the ubiquitin carboxy-terminal hydrolase-L1 genetic polymorphism with the susceptibility of Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD1MXhtVagur7O, PID: 18841579
    • Xiao Y, Zhang B (2008) Association of the ubiquitin carboxy-terminal hydrolase-L1 genetic polymorphism with the susceptibility of Parkinson’s disease. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25:586–587
    • (2008) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.25 , pp. 586-587
    • Xiao, Y.1    Zhang, B.2
  • 28
    • 48749132960 scopus 로고    scopus 로고
    • Lack of evidence for association of a UCH-L1 S18Y polymorphism with Parkinson’s disease in a Han-Chinese population
    • COI: 1:CAS:528:DC%2BD1cXps1Ggtbg%3D, PID: 18638528
    • Zhang ZJ, Burgunder JM, An XK, Wu Y, Chen WJ, Zhang JH (2008) Lack of evidence for association of a UCH-L1 S18Y polymorphism with Parkinson’s disease in a Han-Chinese population. Neurosci Lett 442:200–202
    • (2008) Neurosci Lett , vol.442 , pp. 200-202
    • Zhang, Z.J.1    Burgunder, J.M.2    An, X.K.3    Wu, Y.4    Chen, W.J.5    Zhang, J.H.6
  • 29
    • 0036654541 scopus 로고    scopus 로고
    • ACT and UCH-L1 polymorphisms in Parkinson’s disease and age of onset
    • PID: 12210873
    • Wang J, Zhao CY, Si YM, Liu ZL, Chen B, Yu L (2002) ACT and UCH-L1 polymorphisms in Parkinson’s disease and age of onset. Mov Disord 17:767–771
    • (2002) Mov Disord , vol.17 , pp. 767-771
    • Wang, J.1    Zhao, C.Y.2    Si, Y.M.3    Liu, Z.L.4    Chen, B.5    Yu, L.6
  • 30
    • 33645111633 scopus 로고    scopus 로고
    • Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD28Xis1Shsrg%3D, PID: 16500997
    • Mizuta I, Satake W, Nakabayashi Y, Ito C, Suzuki S, Momose Y et al (2006) Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson’s disease. Hum Mol Genet 15:1151–1158
    • (2006) Hum Mol Genet , vol.15 , pp. 1151-1158
    • Mizuta, I.1    Satake, W.2    Nakabayashi, Y.3    Ito, C.4    Suzuki, S.5    Momose, Y.6
  • 31
    • 33751008344 scopus 로고    scopus 로고
    • Case–control study of UCHL1 S18Y variant in Parkinson’s disease
    • PID: 16941465
    • Tan EK, Puong KY, Fook-Chong S, Chua E, Shen H, Yuen Y (2006) Case–control study of UCHL1 S18Y variant in Parkinson’s disease. Mov Disord 21:1765–1768
    • (2006) Mov Disord , vol.21 , pp. 1765-1768
    • Tan, E.K.1    Puong, K.Y.2    Fook-Chong, S.3    Chua, E.4    Shen, H.5    Yuen, Y.6
  • 32
    • 77952546613 scopus 로고    scopus 로고
    • Ubiquitin specific proteases USP24 and USP40 and ubiquitin thiolesterase UCHL1 polymorphisms have synergic effect on the risk of Parkinson’s disease among Taiwanese
    • COI: 1:CAS:528:DC%2BC3cXlsFOju74%3D, PID: 20302855
    • Wu YR, Chen CM, Chen YC, Chao CY, Ro LS, Fung HC (2010) Ubiquitin specific proteases USP24 and USP40 and ubiquitin thiolesterase UCHL1 polymorphisms have synergic effect on the risk of Parkinson’s disease among Taiwanese. Clin Chim Acta 411:955–958
    • (2010) Clin Chim Acta , vol.411 , pp. 955-958
    • Wu, Y.R.1    Chen, C.M.2    Chen, Y.C.3    Chao, C.Y.4    Ro, L.S.5    Fung, H.C.6
  • 33
    • 79952184830 scopus 로고    scopus 로고
    • Case-control study of the UCH-L1 S18Y variant in sporadic Parkinson’s disease in the Chinese population
    • PID: 21315600
    • Wang L, Guo JF, Nie LL, Luo L, Zuo X, Shen L et al (2011) Case-control study of the UCH-L1 S18Y variant in sporadic Parkinson’s disease in the Chinese population. J Clin Neurosci 18:541–544
    • (2011) J Clin Neurosci , vol.18 , pp. 541-544
    • Wang, L.1    Guo, J.F.2    Nie, L.L.3    Luo, L.4    Zuo, X.5    Shen, L.6
  • 34
    • 84868523706 scopus 로고    scopus 로고
    • UCHL1 S18Y variant is a risk factor for Parkinson’s disease in Japan
    • COI: 1:CAS:528:DC%2BC38XhslCisLzP, PID: 22839974
    • Miyake Y, Tanaka K, Fukushima W, Kiyohara C, Sasaki S, Tsuboi Y et al (2012) UCHL1 S18Y variant is a risk factor for Parkinson’s disease in Japan. BMC Neurol 12:62
    • (2012) BMC Neurol , vol.12 , pp. 62
    • Miyake, Y.1    Tanaka, K.2    Fukushima, W.3    Kiyohara, C.4    Sasaki, S.5    Tsuboi, Y.6
  • 35
    • 0034722106 scopus 로고    scopus 로고
    • The ubiquitin carboxy-terminal hydrolase-L1 gene S18Y polymorphism does not confer protection against idiopathic Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD3cXntF2gt7w%3D, PID: 11027850
    • Mellick GD, Silburn PA (2000) The ubiquitin carboxy-terminal hydrolase-L1 gene S18Y polymorphism does not confer protection against idiopathic Parkinson’s disease. Neurosci Lett 293:127–130
    • (2000) Neurosci Lett , vol.293 , pp. 127-130
    • Mellick, G.D.1    Silburn, P.A.2
  • 36
    • 0034647948 scopus 로고    scopus 로고
    • Mutation analysis and association studies of the UCHL1 gene in German Parkinson’s disease patients
    • COI: 1:CAS:528:DC%2BD3cXls1Ojt74%3D, PID: 10923647
    • Wintermeyer P, Krüger R, Kuhn W, Müller T, Woitalla D, Berg D et al (2000) Mutation analysis and association studies of the UCHL1 gene in German Parkinson’s disease patients. NeuroReport 11:2079–2082
    • (2000) NeuroReport , vol.11 , pp. 2079-2082
    • Wintermeyer, P.1    Krüger, R.2    Kuhn, W.3    Müller, T.4    Woitalla, D.5    Berg, D.6
  • 37
    • 0034864346 scopus 로고    scopus 로고
    • No genetic association of the ubiquitin carboxy-terminal hydrolase-L1 gene S18Y polymorphism with familial Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD3MXotlGjs70%3D, PID: 11716150
    • Levecque C, Destée A, Mouroux V, Becquet E, Defebvre L, Amouyel P (2001) No genetic association of the ubiquitin carboxy-terminal hydrolase-L1 gene S18Y polymorphism with familial Parkinson’s disease. J Neural Transm 108:979–984
    • (2001) J Neural Transm , vol.108 , pp. 979-984
    • Levecque, C.1    Destée, A.2    Mouroux, V.3    Becquet, E.4    Defebvre, L.5    Amouyel, P.6
  • 38
    • 0035859766 scopus 로고    scopus 로고
    • Lack of association between ubiquitin carboxy-terminal hydrolase L1 gene polymorphism and PD
    • COI: 1:STN:280:DC%2BD3MvlslaitA%3D%3D, PID: 11502942
    • Savettieri G, De Marco EV, Civitelli D, Salemi G, Nicoletti G, Annesi G et al (2001) Lack of association between ubiquitin carboxy-terminal hydrolase L1 gene polymorphism and PD. Neurology 57:560–561
    • (2001) Neurology , vol.57 , pp. 560-561
    • Savettieri, G.1    De Marco, E.V.2    Civitelli, D.3    Salemi, G.4    Nicoletti, G.5    Annesi, G.6
  • 39
    • 0345269293 scopus 로고    scopus 로고
    • S18Y polymorphism in the UCH-L1 gene and Parkinson’s disease: evidence for an age-dependent relationship
    • PID: 12539205
    • Elbaz A, Levecque C, Clavel J, Vidal JS, Richard F, Correze JR (2003) S18Y polymorphism in the UCH-L1 gene and Parkinson’s disease: evidence for an age-dependent relationship. Mov Disord 18:130–137
    • (2003) Mov Disord , vol.18 , pp. 130-137
    • Elbaz, A.1    Levecque, C.2    Clavel, J.3    Vidal, J.S.4    Richard, F.5    Correze, J.R.6
  • 41
    • 21044450497 scopus 로고    scopus 로고
    • UCHL1 is associated with Parkinson’s disease: a case-unaffected sibling and case-unrelated control study
    • COI: 1:CAS:528:DC%2BD2MXktVOmtLg%3D, PID: 15882803
    • Facheris M, Strain KJ, Lesnick TG, de Andrade M, Bower JH, Ahlskog JE et al (2005) UCHL1 is associated with Parkinson’s disease: a case-unaffected sibling and case-unrelated control study. Neurosci Lett 381:131–134
    • (2005) Neurosci Lett , vol.381 , pp. 131-134
    • Facheris, M.1    Strain, K.J.2    Lesnick, T.G.3    de Andrade, M.4    Bower, J.H.5    Ahlskog, J.E.6
  • 42
    • 38349134580 scopus 로고    scopus 로고
    • Lack of evidence for an association between UCHL1 S18Y and Parkinson’s disease
    • PID: 18093156
    • Hutter CM, Samii A, Factor SA, Nutt JG, Higgins DS, Bird TD et al (2008) Lack of evidence for an association between UCHL1 S18Y and Parkinson’s disease. Eur J Neurol 15:134–139
    • (2008) Eur J Neurol , vol.15 , pp. 134-139
    • Hutter, C.M.1    Samii, A.2    Factor, S.A.3    Nutt, J.G.4    Higgins, D.S.5    Bird, T.D.6
  • 43
    • 34347257768 scopus 로고    scopus 로고
    • S18Y in ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) associated with decreased risk of Parkinson’s disease in Sweden
    • PID: 17287139
    • Carmine Belin A, Westerlund M, Bergman O, Nissbrandt H, Lind C, Sydow O (2007) S18Y in ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) associated with decreased risk of Parkinson’s disease in Sweden. Parkinsonism Relat Disord 13:295–298
    • (2007) Parkinsonism Relat Disord , vol.13 , pp. 295-298
    • Carmine Belin, A.1    Westerlund, M.2    Bergman, O.3    Nissbrandt, H.4    Lind, C.5    Sydow, O.6
  • 44
    • 78349294117 scopus 로고    scopus 로고
    • Exploration of genetic susceptibility factors for Parkinson’s disease in a South American sample
    • PID: 20861575
    • Benitez BA, Forero DA, Arboleda GH, Granados LA, Yunis JJ, Fernandez W et al (2010) Exploration of genetic susceptibility factors for Parkinson’s disease in a South American sample. J Genet 89:229–232
    • (2010) J Genet , vol.89 , pp. 229-232
    • Benitez, B.A.1    Forero, D.A.2    Arboleda, G.H.3    Granados, L.A.4    Yunis, J.J.5    Fernandez, W.6
  • 45
    • 84887624616 scopus 로고    scopus 로고
    • Analysis of genome-wide association study-linked loci in Parkinson’s disease of Mainland China
    • COI: 1:CAS:528:DC%2BC3sXhsl2hur%2FL, PID: 23853107
    • Liu J, Xiao Q, Wang Y, Xu ZM, Wang Y, Yang Q (2013) Analysis of genome-wide association study-linked loci in Parkinson’s disease of Mainland China. Mov Disord 28:1892–1895
    • (2013) Mov Disord , vol.28 , pp. 1892-1895
    • Liu, J.1    Xiao, Q.2    Wang, Y.3    Xu, Z.M.4    Wang, Y.5    Yang, Q.6
  • 46
    • 84858667775 scopus 로고    scopus 로고
    • Genetic basis of Parkinson’s disease: inheritance, penetrance, and expression
    • COI: 1:CAS:528:DC%2BC3MXnt1Gqtbg%3D, PID: 23776368
    • Schulte C, Gasser T (2011) Genetic basis of Parkinson’s disease: inheritance, penetrance, and expression. Appl Clin Genet 4:67–80
    • (2011) Appl Clin Genet , vol.4 , pp. 67-80
    • Schulte, C.1    Gasser, T.2
  • 47
    • 64849090236 scopus 로고    scopus 로고
    • Causative gene and its associated gene for Parkinson disease and dystonia
    • COI: 1:CAS:528:DC%2BD1MXmsFKrsbo%3D, PID: 19378815
    • Hasegawa K, Toyoshima I (2009) Causative gene and its associated gene for Parkinson disease and dystonia. Brain Nerve 61:447–463
    • (2009) Brain Nerve , vol.61 , pp. 447-463
    • Hasegawa, K.1    Toyoshima, I.2
  • 48
    • 0037131567 scopus 로고    scopus 로고
    • The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson’s disease susceptibility
    • COI: 1:CAS:528:DC%2BD38Xotlahsr0%3D, PID: 12408865
    • Liu Y, Fallon L, Lashuel HA, Liu Z, Lansbury PT Jr (2002) The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson’s disease susceptibility. Cell 111:209–218
    • (2002) Cell , vol.111 , pp. 209-218
    • Liu, Y.1    Fallon, L.2    Lashuel, H.A.3    Liu, Z.4    Lansbury, P.T.5
  • 49
    • 0037466510 scopus 로고    scopus 로고
    • Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants
    • COI: 1:CAS:528:DC%2BD3sXivV2nu7w%3D, PID: 12705903
    • Nishikawa K, Li H, Kawamura R, Osaka H, Wang YL, Hara Y et al (2003) Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants. Biochem Biophys Res Commun 304:176–183
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 176-183
    • Nishikawa, K.1    Li, H.2    Kawamura, R.3    Osaka, H.4    Wang, Y.L.5    Hara, Y.6
  • 50
    • 5444235520 scopus 로고    scopus 로고
    • Genetic causes of Parkinson’s disease: uCHL-1
    • COI: 1:CAS:528:DC%2BD2cXos1aqsLs%3D, PID: 15221445
    • Healy DG, Abou-Sleiman PM, Wood NW (2004) Genetic causes of Parkinson’s disease: uCHL-1. Cell Tissue Res 318:189–194
    • (2004) Cell Tissue Res , vol.318 , pp. 189-194
    • Healy, D.G.1    Abou-Sleiman, P.M.2    Wood, N.W.3
  • 52
    • 41149151293 scopus 로고    scopus 로고
    • Exploring gene-environment interactions in Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD1cXjsFGiur0%3D, PID: 18210157
    • McCulloch CC, Kay DM, Factor SA, Samii A, Nutt JG, Higgins DS et al (2008) Exploring gene-environment interactions in Parkinson’s disease. Hum Genet 123:257–265
    • (2008) Hum Genet , vol.123 , pp. 257-265
    • McCulloch, C.C.1    Kay, D.M.2    Factor, S.A.3    Samii, A.4    Nutt, J.G.5    Higgins, D.S.6
  • 53
    • 0026514953 scopus 로고
    • Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: a clinico-pathological study of 100 cases
    • COI: 1:STN:280:DyaK383is1Omsg%3D%3D, PID: 1564476
    • Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992) Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55:181–184
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , pp. 181-184
    • Hughes, A.J.1    Daniel, S.E.2    Kilford, L.3    Lees, A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.