Recovery of walking ability using a robotic device in subacute stroke patients: A randomized controlled study

Disability and Rehabilitation: Assistive Technology

Volumn 10, Issue 2, 2015, Pages 141-148

  Van Nunen, Michiel P M ^a,b   Gerrits, Karin H L ^a,b   Konijnenbelt, Manin ^b   Janssen, Thomas W J ^a,b   De Haan, Arnold ^a,c  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b Amsterdam Rehabilitation Research Center Reade   (Netherlands)

^c MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

Lokomat; Randomized controlled trial; Stroke; Walking

Indexed keywords

ADULT; CONTROLLED STUDY; CONVALESCENCE; DEVICES; FEMALE; HUMAN; MALE; MIDDLE AGED; PHYSIOTHERAPY; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; ROBOTICS; STROKE; WALKING;

ADULT; FEMALE; HUMANS; MALE; MIDDLE AGED; PHYSICAL THERAPY MODALITIES; QUALITY OF LIFE; RECOVERY OF FUNCTION; ROBOTICS; STROKE; WALKING;

EID: 84922059062     PISSN: 17483107     EISSN: 17483115     Source Type: Journal    
DOI: 10.3109/17483107.2013.873489     Document Type: Article

References (41)

1. Roerdink M, Beek PJ. Understanding inconsistent step-length asymmetries across hemiplegic stroke patients: impairments and compensatory gait. Neurorehabil Neural Repair 2011;25:253-8.
2. Patterson KK, Gage WH, Brooks D, et al. Changes in gait symmetry and velocity after stroke: a cross-sectional study from weeks to years after stroke. Neurorehabil Neural Repair 2010;24:783-90.
3. Belda-Lois JM, Mena-del Horno S, Bermejo-Bosch I, et al. Rehabilitation of gait after stroke: a review towards a top-down approach. J Neuroeng Rehabil 2011;8:66 (1-19).
4. Van de Port IG, Wood-Dauphinee S, Lindeman E, Kwakkel G. Effects of exercise training programs on walking competency after stroke: a systematic review. Am J Phys Med Rehabil 2007;86:935-51.
5. Langhorne P, Bernhardt J, Kwakkel G. Stroke rehabilitation. The Lancet 2011;377:1693-702.
6. Moseley AM, Stark A, Cameron ID, Pollock A. Treadmill training and body weight support for walking after stroke. Cochrane Database Syst Rev 2005;4:CD002840.
7. Mehrholz J, Werner C, Kugler J, Pohl M. Electromechanical-assisted training for walking after stroke. Cochrane Database Syst Rev 2007;4:CD006185.
8. Hesse S. Treadmill training with partial body weight support after stroke. NeuroRehabilitation 2008;23:55-65.
9. Colombo G, Wirz M, Dietz V. Driven gait orthosis for improvement of locomotor training in paraplegic patients. Spinal Cord 2001;39:252-5.
10. Hidler J. Automating activity-based interventions: the role of robotics. J Rehabil Res Dev 2008;45:337-44.
11. Hornby TG, Campbell DD, Kahn JH, et al. Enhanced gait-related improvements after therapist- versus robotic-assisted locomotor training in subjects with chronic stroke: a randomized controlled study. Stroke 2008;39:1786-92.
12. Colombo G, Joerg M, Schreier R, Dietz V. Treadmill training of paraplegic patients using a robotic orthosis. J Rehabil Res Dev 2000; 37:693-700.
13. Veneman JF, Kruidhof R, Hekman EE, et al. Design and evaluation of the LOPES exoskeleton robot for interactive gait rehabilitation. IEEE Trans Neural Syst Rehabil Eng 2007;15:379-86.
14. Mayr A, Kofler M, Quirbach E, et al. Prospective, blinded, randomized crossover study of gait rehabilitation in stroke patients using the Lokomat gait orthosis. Neurorehabil Neural Repair 2007; 21:307-14.
15. Husemann B, Müller F, Krewer C, et al. Effects of locomotion training with assistance of a robot-driven gait orthosis in hemiparetic patients after stroke: a randomized controlled pilot study. Stroke 2007;38:349-54.
16. Hidler J, Nichols D, Pelliccio M, et al. Multicenter randomized clinical trial evaluating the effectiveness of the Lokomat in subacute stroke. Neurorehabil Neural Repair 2009;23:5-13.
17. Schwartz I, Sajin A, Fisher I, et al. The effectiveness of locomotor therapy using robotic-assisted gait training in subacute stroke patients: a randomized controlled trial. PM&R 2009;1:516-23.
18. Westlake KP, Patten C. Pilot study of Lokomat versus manual-assisted treadmill training for locomotor recovery post-stroke. J Neuroeng Rehabil 2009;6:18 (1-11).
19. Chang WH, Kim MS, Huh JP, et al. Effects of robot-assisted gait training on cardiopulmonary fitness in subacute stroke patients: a randomized controlled study. Neurorehabil Neural Repair 2012;26:318-24.
20. Krakauer JW, Carmichael ST, Corbett D, Wittenberg GF. Getting neurorehabilitation right what can be learned from animal models? Neurorehabil Neural Repair 2012;26:923-31.
21. Cai LL, Fong AJ, Otoshi CK, et al. Implications of assist-as-needed robotic step training after a complete spinal cord injury on intrinsic strategies of motor learning. J Neurosci 2006;26:10564-8.
22. Duncan PW, Sullivan KJ, Behrman AL, et al. Body-weightsupported treadmill rehabilitation after stroke. N Eng J Med 2011;364:2026-36.
23. Behrman AL, Lawless-Dixon AR, Davis SB, et al. Locomotor training progression and outcomes after incomplete spinal cord injury. Phys Ther 2005;85:1356-71.
24. Pohl M, Werner C, Holzgraefe M, et al. Repetitive locomotor training and physiotherapy improve walking and basic activities of daily living after stroke: a single-blind, randomized multicentre trial (DEutsche GAngtrainerStudie, DEGAS). Clin Rehabil 2007;21:17-27.
25. Peppen RPS, Kwakkel G, Harmeling-vander Wel B, et al. KNGF Clinical Practice Guideline for physical therapy in patients with stroke. Review of the evidence [Translation 2008]. Nederlands Tijdschrift voor Fysiotherapie 2004;2004:126-53.
26. Horstman AM, Beltman MJ, Gerrits KH, et al. Intrinsic muscle strength and voluntary activation of both lower limbs and functional performance after stroke. Clin Physiol Funct Imaging 2008;28:251-61.
27. Twisk JW, de Vente W. The analysis of randomised controlled trial data with more than one follow-up measurement. A comparison between different approaches. Eur J Epidemiol 2008;23:655-60.
28. Vickers AJ. Parametric versus non-parametric statistics in the analysis of randomized trials with non-normally distributed data. BMC Med Res Methodol 2005;5:35.
29. Van Breukelen GJ. ANCOVA versus change from baseline: more power in randomized studies, more bias in nonrandomized studies [corrected]. J Clin Epidemiol 2006;59:920-5.
30. Field A. Discovering statistics using SPSS. London, England: Sage Publications Limited; 2009.
31. Kollen B, van de Port I, Lindeman E, et al. Predicting improvement in gait after stroke: a longitudinal prospective study. Stroke 2005;36:2676-80.
32. Kwakkel G, Kollen BJ, Wagenaar RC. Understanding the pattern of functional recovery after stroke facts and theories. Restorative Neurol Neurosci 2004;22:281-99.
33. Dean CM, Ada L, Bampton J, et al. Treadmill walking with body weight support in subacute non-ambulatory stroke improves walking capacity more than overground walking: a randomised trial. J Physiother 2010;56:97-103.
34. Ada L, Dean CM, Morris ME, et al. Randomized trial of treadmill walking with body weight support to establish walking in subacute stroke: the MOBILISE trial. Stroke 2010;41:1237-42.
35. Franceschini M, Carda S, Agosti M, et al. Walking after stroke: what does treadmill training with body weight support add to overground gait training in patients early after stroke? A single-blind, randomized, controlled trial. Stroke 2009;40:3079-85.
36. Veerbeek JM, Koolstra M, Ket JCF, et al. Effects of augmented exercise therapy on outcome of gait and gait-related in the first 6 months after stroke. A meta-analysis. Stroke 2011;42:3311-15.
37. Kwakkel G, Kollen BJ, Wagenaar RC. Long term effects of intensity of arm and leg training in stroke patients. J Neurol Neurosurg Psychiatry 2002;72:473-9.
38. Dobkin BH, Duncan PW. Should body weight-supported treadmill training and robotic-assistive steppers for locomotor training trot back to the starting gate? Neurorehabil Neural Repair 2012;26:308-7.
39. Schuck A, Labruyère R, Vallery H, et al. Feasibility and effects of patient-cooperative robot-aided gait training applied in a 4-week pilot trial. J Neuroeng Rehabil 2012;9:31 (1-14).
40. Zorner B, Schwab ME. Anti-Nogo on the go: from animal models to a clinical trial. Ann N Y Acad Sci 2010;1198:E22-34.
41. Rogers LM, Madhavan S, Roth H, Stinear JW. Transforming neurorehabilitation of walking following stroke: the promise of non-invasive brain stimulation - a review. Restor Neurol Neurosci 2011;29:507-16.