Paenilamicin: Structure and biosynthesis of a hybrid nonribosomal peptide/polyketide antibiotic from the bee pathogen paenibacillus larvae

Angewandte Chemie - International Edition

Volumn 53, Issue 40, 2014, Pages 10821-10825

  Müller, Sebastian ^a   Garcia Gonzalez, Eva ^b   Mainz, Andi ^a   Hertlein, Gillian ^b   Heid, Nina C ^b   Mösker, Eva ^a   Van Den Elst, Hans ^c   Overkleeft, Herman S ^c   Genersch, Elke ^b,d   Süssmuth, Roderich D ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b Institute for Bee Research   (Germany)

^c LEIDEN UNIVERSITY   (Netherlands)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

antibacterial agents; nonribosomal peptide synthesis; Paenibacillus larvae; polyketide synthesis; virulence factors

Indexed keywords

BACTERIA; BIOCHEMISTRY; FOOD PRODUCTS; FUNGI; GENES; KETONES; MACHINERY; METABOLITES; PEPTIDES;

ANTI-BACTERIAL AGENTS; NONRIBOSOMAL PEPTIDE; PAENIBACILLUS LARVAE; POLYKETIDE SYNTHESIS; VIRULENCE FACTORS;

BIOSYNTHESIS;

ANTIINFECTIVE AGENT; PEPTIDE; POLYKETIDE; VIRULENCE FACTOR;

ANIMAL; BACTERIAL GENE; BEE; BIOSYNTHESIS; CHEMISTRY; GENETICS; GRAM POSITIVE INFECTION; GROWTH, DEVELOPMENT AND AGING; LARVA; METABOLISM; MICROBIOLOGY; MULTIGENE FAMILY; PAENIBACILLUS; PATHOGENICITY; VETERINARY;

ANIMALS; ANTI-BACTERIAL AGENTS; BEES; BIOSYNTHETIC PATHWAYS; GENES, BACTERIAL; GRAM-POSITIVE BACTERIAL INFECTIONS; LARVA; MULTIGENE FAMILY; PAENIBACILLUS; PEPTIDES; POLYKETIDES; VIRULENCE FACTORS;

EID: 84922034920     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201404572     Document Type: Article

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