Gut symbionts from distinct hosts exhibit genotoxic activity via divergent colibactin biosynthesis pathways

Applied and Environmental Microbiology

Volumn 81, Issue 4, 2015, Pages 1502-1512

  Engel, Philipp ^a,c   Vizcaino, Maria I ^a   Crawford, Jason M ^a,b  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOMOLECULES; BIOSYNTHESIS; DISEASES; ESCHERICHIA COLI; GENES; KETONES; MAMMALS;

BIOSYNTHESIS PATHWAYS; COMPARATIVE METABOLOMICS; FUNCTIONAL CAPABILITIES; MICROBIAL INTERACTIONS; NONRIBOSOMAL PEPTIDE SYNTHETASES; POLYKETIDE SYNTHASES; SECONDARY METABOLITES; SYMBIOTIC ASSOCIATION;

METABOLITES;

BIOTECHNOLOGY; CANCER; FECAL COLIFORM; GENOTOXICITY; PEPTIDE; SECONDARY METABOLITE; SYMBIONT; TUMOR;

ANIMALIA; APIS MELLIFERA; BACTERIA (MICROORGANISMS); ENTEROBACTERIACEAE; ESCHERICHIA COLI; EUKARYOTA; MAMMALIA; PSEUDOVIBRIO;

COLIBACTIN; PEPTIDE; POLYKETIDE;

ANIMAL; BEE; BIOSYNTHESIS; CLASSIFICATION; COMPARATIVE STUDY; DNA DAMAGE; DRUG EFFECTS; ENTEROBACTERIACEAE; ESCHERICHIA COLI; GAMMAPROTEOBACTERIA; GASTROINTESTINAL TRACT; GENETICS; GENOMIC ISLAND; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; PHYLOGENY; RHODOBACTERACEAE; SPECIES DIFFERENCE; SYMBIOSIS;

ANIMALS; BEES; BIOSYNTHETIC PATHWAYS; DNA DAMAGE; ENTEROBACTERIACEAE; ESCHERICHIA COLI; GAMMAPROTEOBACTERIA; GASTROINTESTINAL TRACT; GENOMIC ISLANDS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDES; PHYLOGENY; POLYKETIDES; RHODOBACTERACEAE; SPECIES SPECIFICITY; SYMBIOSIS;

EID: 84922023867     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.03283-14     Document Type: Article

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