Acquired cystic disease-associated renal cell carcinoma with a focal sarcomatoid component: Report of a case showing more pronounced polysomy of chromosomes 3 and 16 in the sarcomatoid component

Pathology International

Volumn 65, Issue 2, 2015, Pages 89-94

  Tajima, Shogo ^a,c   Waki, Michihiko ^b   Doi, Wataru ^a   Hayashi, Kazumasa ^a   Takenaka, Syunsuke ^a   Fukaya, Yoshie ^a   Kimura, Ryosuke ^a  

^a SHIZUOKA SAISEIKAI GENERAL HOSPITAL   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Acquired cystic disease associated renal cell carcinoma; Chromosome 16; Chromosome 3; E cadherin; N cadherin; Polysomy; Sarcomatoid

Indexed keywords

PROTEIN P53; TP53 PROTEIN, HUMAN;

ACQUIRED CYSTIC DISEASE ASSOCIATED RENAL CELL CARCINOMA; AGED; ARTICLE; CANCER GROWTH; CANCER SIZE; CASE REPORT; CHROMOSOME 16; CHROMOSOME 16 POLYSOMY; CHROMOSOME 3; CHROMOSOME 3 POLYSOMY; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; LAPAROSCOPY; MALE; NEPHRECTOMY; NUMERICAL CHROMOSOME ABERRATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SARCOMATOID CARCINOMA; TRISOMY; TUMOR INVASION; CHROMOSOME ABERRATION; COMPLICATION; GENETICS; KIDNEY POLYCYSTIC DISEASE; KIDNEY TUMOR; PATHOLOGY;

AGED; CARCINOMA, RENAL CELL; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 16; CHROMOSOMES, HUMAN, PAIR 3; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KIDNEY DISEASES, CYSTIC; KIDNEY NEOPLASMS; MALE; TRISOMY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84921953877     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/pin.12232     Document Type: Article

References (20)

1. Truong LD, Krishnan B, Cao JT, Barrios R, Suki WN. Renal neoplasm in acquired cystic kidney disease. Am J Kidney Dis 1995; 26: 1-12.
2. Hughson MD, Schmidt L, Zbar B etal. Renal cell carcinoma of end-stage renal disease: A histopathologic and molecular genetic study. J Am Soc Nephrol 1996; 7: 2461-2468.
3. Truong LD, Choi YJ, Shen SS, Ayala G, Amato R, Krishnan B. Renal cystic neoplasms and renal neoplasms associated with cystic renal diseases: Pathogenetic and molecular links. Adv Anat Pathol 2003; 10: 135-159.
4. Sule N, Yakupoglu U, Shen SS etal. Calcium oxalate deposition in renal cell carcinoma associated with acquired cystic kidney disease: A comprehensive study. Am J Surg Pathol 2005; 29: 443-451.
5. Petrolla AA, Maclennan GT. Renal cell carcinoma associated with end stage renal disease. J Urol 2006; 176: 345.
6. Tickoo SK, dePeralta-Venturina MN, Harik LR etal. Spectrum of epithelial neoplasms in end-stage renal disease: An experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. Am J Surg Pathol 2006; 30: 141-153.
7. Kuroda N, Ohe C, Mikami S etal. Review of acquired cystic disease-associated renal cell carcinoma with focus on pathobiological aspects. Histol Histopathol 2011; 26: 1215-1218.
8. Kuroda N, Yamashita M, Kakehi Y, Hes O, Michal M, Lee GH. Acquired cystic disease-associated renal cell carcinoma: An immunohistochemical and fluorescence in situ hybridization study. Med Mol Morphol 2011; 44: 228-232.
9. Suvarna SK, Ahuja M, Brown CB. Sarcomatoid renal cell carcinoma arising in hemodialysis-associated acquired cystic kidney disease presenting with disseminated bone marrow infiltration. Am J Kidney Dis 1994; 24: 581-585.
10. Kuroda N, Tamura M, Taguchi T etal. Sarcomatoid acquired cystic disease-associated renal cell carcinoma. Histol Histopathol 2008; 23: 1327-1331.
11. Kuroda N, Tamura M, Hamaguchi N etal. Acquired cystic disease-associated renal cell carcinoma with sarcomatoid change and rhabdoid features. Ann Diagn Pathol 2011; 15: 462-466.
12. Rioux-Leclercq NC, Epstein JI. Renal cell carcinoma with intratumoral calcium oxalate crystal deposition in patients with acquired cystic disease of the kidney. Arch Pathol Lab Med 2003; 127: E89-92.
13. Hosseini M, Antic T, Paner GP, Chang A. Pathologic spectrum of cysts in end-stage kidneys: Possible precursors to renal neoplasia. Hum Pathol 2014; 45: 1406-1413.
14. Pan CC, Chen YJ, Chang LC, Chang YH, Ho DM. Immunohistochemical and molecular genetic profiling of acquired cystic disease-associated renal cell carcinoma. Histopathology 2009; 55: 145-153.
15. Behnes CL, Hemmerlein B, Strauss A, Radzun HJ, Bremmer F. N-cadherin is differentially expressed in histological subtypes of papillary renal cell carcinoma. Diagn Pathol 2012; 7: 95-100.
16. Prozialeck WC, Lamar PC, Appelt DM. Differential expression of E-cadherin, N-cadherin and beta-catenin in proximal and distal segments of the rat nephron. BMC Physiol 2004; 4: 10.
17. Kuroda N, Shiotsu T, Hes O, Michal M, Shuin T, Lee GH. Acquired cystic disease-associated renal cell carcinoma with gain of chromosomes 3, 7, and 16, gain of chromosome X, and loss of chromosome Y. Med Mol Morphol 2010; 43: 231-234.
18. Kuroda N, Toi M, Hiroi M, Enzan H. Review of sarcomatoid renal cell carcinoma with focus on clinical and pathobiological aspects. Histol Histopathol 2003; 18: 551-555.
19. Oda H, Nakatsuru Y, Ishikawa T. Mutations of the p53 gene and p53 protein overexpression are associated with sarcomatoid transformation in renal cell carcinomas. Cancer Res 1995; 55: 658-662.
20. Ricke RM, van Deursen JM. Aneuploidy in health, disease, and aging. J Cell Biol 2013; 201: 11-21.