Abnormal activation of the social brain network in children with autism spectrum disorder: An fMRI study

Psychiatry Investigation

Volumn 12, Issue 1, 2015, Pages 37-45

  Kim, Sun Young ^a   Choi, Uk Su ^b   Park, Sung Yeon ^b   Oh, Se Hong ^b   Yoon, Hyo Woon ^c   Koh, Yun Joo ^d   Im, Woo Young ^e   Park, Jee In ^f   Song, Dong Ho ^f   Cheon, Keun Ah ^f   Lee, Chang Uk ^g  

^a Sungmo maum Oriental Clinic   (South Korea)

^b Gachon University   (South Korea)

^c Daegu Cyber University   (South Korea)

^d The Korea Institute for Children's Social Development   (South Korea)

^e Konyang University College of Medicine   (South Korea)

^f Yonsei University College of Medicine   (South Korea)

^g The Catholic University of Korea   (South Korea)

Author keywords

Autism spectrum disorder; FMRI; Social brain network; Social cognition

Indexed keywords

METHYLPHENIDATE; VALPROIC ACID;

ARACHNOID CYST; ARTICLE; ATTENTION DEFICIT DISORDER; ATTENTION DISTURBANCE; AUTISM; AUTISM DIAGNOSTIC INTERVIEW REVISED; AUTISM DIAGNOSTIC OBSERVATION SCHEDULE; AUTISM SPECTRUM SCREENING QUESTIONNAIRE; CHILD; CLINICAL ARTICLE; CONTINUOUS PERFORMANCE TEST; CONTROLLED STUDY; DSM-IV-TR; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; IMPULSIVENESS; INTELLECTUAL IMPAIRMENT; INTERVIEW; KOREA; MALE; MOOD DISORDER; PSYCHOLOGIC ASSESSMENT; PSYCHOLOGIC TEST; SCHEDULE FOR AFFECTIVE DISORDERS AND SCHIZOPHRENIA; SEMI STRUCTURED INTERVIEW; SOCIAL ADAPTATION; SOCIAL COGNITION; SOCIAL INTERACTION; SOCIAL RESPONSIVENESS SCALE; WECHSLER INTELLIGENCE SCALE;

EID: 84921950904     PISSN: 17383684     EISSN: 19763026     Source Type: Journal    
DOI: 10.4306/pi.2015.12.1.37     Document Type: Article

References (40)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, DSM-V. Washington, DC:American Psychiatric Association; 2013.
2. Philip RC, Dauvermann MR, Whalley HC, Baynham K, Lawrie SM, Stanfield AC. A systematic review and meta-analysis of the fMRI investigation of autism spectrum disorders. Neurosci Biobehav Rev 2012; 36:901-942.
3. Sato W, Toichi M, Uono S, Kochiyama T. Impaired social brain network for processing dynamic facial expressions in autism spectrum disorders. BMC Neurosci 2012;13:99.
4. Burnett S, Sebastian C, Cohen Kadosh K, Blakemore SJ. The social brain in adolescence: evidence from functional magnetic resonance imaging and behavioural studies. Neurosci Biobehav Rev 2011;35:1654-1664.
5. Johnson MH, Griffin R, Csibra G, Halit H, Farroni T, de Haan M, et al. The emergence of the social brain network: evidence from typical and atypical development. Dev Psychopathol 2005;17:599-619.
6. Ashwin C, Baron-Cohen S, Wheelwright S, O’Riordan M, Bullmore ET. Differential activation of the amygdala and the ‘social brain’ during fearful face-processing in Asperger Syndrome. Neuropsychologia 2007; 45:2-14.
7. Wang AT, Lee SS, Sigman M, Dapretto M. Reading affect in the face and voice: neural correlates of interpreting communicative intent in children and adolescents with autism spectrum disorders. Arch Gen Psychiatry 2007;64:698-708.
8. Wang AT, Dapretto M, Hariri AR, Sigman M, Bookheimer SY. Neural correlates of facial affect processing in children and adolescents with autism spectrum disorder. J Am Acad Child Adolesc Psychiatry 2004; 43:481-490.
9. Hein G, Singer T. I feel how you feel but not always: the empathic brain and its modulation. Curr Opin Neurobiol 2008;18:153-158.
10. Frith U, Frith CD. Development and neurophysiology of mentalizing. Philos Trans R Soc Lond B Biol Sci 2003;358:459-473.
11. Frith CD, Frith U. The neural basis of mentalizing. Neuron 2006;50: 531-534.
12. Vuilleumier P, Pourtois G. Distributed and interactive brain mechanisms during emotion face perception: evidence from functional neuroimaging. Neuropsychologia 2007;45:174-194.
13. Carr L, Iacoboni M, Dubeau MC, Mazziotta JC, Lenzi GL. Neural mechanisms of empathy in humans: a relay from neural systems for imitation to limbic areas. Proc Natl Acad Sci U S A 2003;100:5497-5502.
14. Rizzolatti G, Fogassi L, Gallese V. Neurophysiological mechanisms underlying the understanding and imitation of action. Nat Rev Neurosci 2001;2:661-670.
15. Kim YS, Leventhal BL, Koh YJ, Fombonne E, Laska E, Lim EC, et al. Prevalence of autism spectrum disorders in a total population sample. Am J Psychiatry 2011;168:904-912.
16. Ehlers S, Gillberg C, Wing L. A screening questionnaire for Asperger syndrome and other high-functioning autism spectrum disorders in school age children. J Autism Dev Disord 1999;29:129-141.
17. Lord C, Rutter M, Le Couteur A. Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 1994;24:659-685.
18. Lord C, Risi S, Lambrecht L, Cook EH Jr, Leventhal BL, DiLavore PC, et al. The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord 2000;30:205-223.
19. Kim YS, Cheon KA, Kim BN, Chang SA, Yoo HJ, Kim JW, et al. The reliability and validity of Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean version (K-SADS-PL-K). Yonsei Med J 2004;45:81-89.
20. Constantino JN, Davis SA, Todd RD, Schindler MK, Gross MM, Brophy SL, et al. Validation of a brief quantitative measure of autistic traits: comparison of the social responsiveness scale with the autism diagnostic interview-revised. J Autism Dev Disord 2003;33:427-433.
21. Lang PJ, Bradely MM, Cuthbert BN. International Affective Picture System (IAPS): affective ratings of pictures and instruction manual. Technical Report A-8. Gainesville: University of Florida; 2008.
22. Gazzaniga MS, Ivry RB, Mangun GR. Cognitive Neuroscience: The Biology of the Mind. New York: Norton & Company; 2008.
23. Oberman LM, Ramachandran VS. The simulating social mind: the role of the mirror neuron system and simulation in the social and communicative deficits of autism spectrum disorders. Psychol Bull 2007; 133:310-327.
24. Iacoboni M, Woods RP, Brass M, Bekkering H, Mazziotta JC, Rizzolatti G. Cortical mechanisms of human imitation. Science 1999;286:2526-2528.
25. Williams JH, Whiten A, Suddendorf T, Perrett DI. Imitation, mirror neurons and autism. Neurosci Biobehav Rev 2001;25:287-295.
26. Ramachandran VS, Oberman LM. Broken mirrors: a theory of autism. Sci Am 2006;295:62-69.
27. Dapretto M, Davies MS, Pfeifer JH, Scott AA, Sigman M, Bookheimer SY, et al. Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disorders. Nat Neurosci 2006; 9:28-30.
28. Williams JH, Waiter GD, Gilchrist A, Perrett DI, Murray AD, Whiten A. Neural mechanisms of imitation and ‘mirror neuron’ functioning in autistic spectrum disorder. Neuropsychologia 2006;44:610-621.
29. Craig AD. How do you feel--now? The anterior insula and human awareness. Nat Rev Neurosci 2009;10:59-70.
30. Pollatos O, Gramann K, Schandry R. Neural systems connecting interoceptive awareness and feelings. Hum Brain Mapp 2007;28:9-18.
31. Critchley HD, Wiens S, Rotshtein P, Ohman A, Dolan RJ. Neural systems supporting interoceptive awareness. Nat Neurosci 2004;7:189-195.
32. Ebisch SJ, Gallese V, Willems RM, Mantini D, Groen WB, Romani GL, et al. Altered intrinsic functional connectivity of anterior and posterior insula regions in high-functioning participants with autism spectrum disorder. Hum Brain Mapp 2011;32:1013-1028.
33. Silani G, Bird G, Brindley R, Singer T, Frith C, Frith U. Levels of emotional awareness and autism: an fMRI study. Soc Neurosci 2008;3:97-112.
34. Gur RC, Schroeder L, Turner T, McGrath C, Chan RM, Turetsky BI, et al. Brain activation during facial emotion processing. Neuroimage 2002; 16:651-662.
35. Schultz RT. Developmental deficits in social perception in autism: the role of the amygdala and fusiform face area. Int J Dev Neurosci 2005; 23:125-141.
36. Smith SD, Bulman-Fleming MB. A hemispheric asymmetry for the unconscious perception of emotion. Brain Cogn 2004;55:452-457.
37. Davidson RJ. Cerebral Asymmetries, Emotion, and Affective Style. Cambridge: MIT Press; 1995.
38. Smith SD, Bulman-Fleming MB. An examination of the right-hemisphere hypothesis of the lateralization of emotion. Brain Cogn 2005; 57:210-213.
39. Fusar-Poli P, Placentino A, Carletti F, Landi P, Allen P, Surguladze S, et al. Functional atlas of emotional faces processing: a voxel-based meta-analysis of 105 functional magnetic resonance imaging studies. J Psychiatry Neurosci 2009;34:418-432.
40. Lieberman MD, Cuningham WA. Type I and Type II error concerns in fMRI research: re-balancing the scale. Soc Cogn Affect Neurosci 2009; 4:423-428.