Budesonide-loaded guar gum microspheres for colon delivery: Preparation, characterization and in vitro/in vivo evaluation

International Journal of Molecular Sciences

Volumn 16, Issue 2, 2015, Pages 2693-2704

  Liu, Ye ^a   Zhou, Hong ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Budesonide; Colon delivery; In vitro release; Microspheres; Pharmacokinetics

Indexed keywords

BUDESONIDE; GUAR GUM MICROSPHERE; MICROSPHERE; UNCLASSIFIED DRUG; DRUG CARRIER; GALACTAN; GUAR GUM; MANNAN; PLANT GUM;

ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; COLON DRUG DELIVERY SYSTEM; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG HALF LIFE; DRUG SOLUBILITY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LASER DIFFRACTION; LOADING TEST; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PARTICLE SIZE; RAT; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; ANIMAL; CHEMISTRY; COLON; HALF LIFE TIME; METABOLISM; ORAL DRUG ADMINISTRATION; PATHOLOGY; PH; RECEIVER OPERATING CHARACTERISTIC; SMALL INTESTINE; SPRAGUE DAWLEY RAT; STOMACH;

CYAMOPSIS TETRAGONOLOBA;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BUDESONIDE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLON; DRUG CARRIERS; GALACTANS; HALF-LIFE; HYDROGEN-ION CONCENTRATION; INTESTINE, SMALL; MANNANS; MICROSPHERES; PARTICLE SIZE; PLANT GUMS; RATS; RATS, SPRAGUE-DAWLEY; ROC CURVE; STOMACH;

EID: 84921928366     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms16022693     Document Type: Article

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