Activation of prostaglandin e2 -ep4 signaling reduces chemokine production in adipose tissue

Journal of Lipid Research

Volumn 56, Issue 2, 2015, Pages 358-368

  Tang, Eva H C ^a,b   Cai, Yin ^a   Wong, Chi Kin ^a   Rocha, Viviane Z ^c   Sukhova, Galina K ^a,b   Shimizu, Koichi ^b   Xuan, Ge ^a,d   Vanhoutte, Paul M ^a,e   Libby, Peter ^b   Xu, Aimin ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b The Research Centre of Heart Brain Hormone and Healthy Aging The University of Hong Kong ^*  (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Chemokines; Eicosanoids; EP4 receptor; Fat; Prostanoids

Indexed keywords

CAY 10580; CD8 ANTIGEN; CHEMOKINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOSOLIC PROSTAGLANDIN E2 SYNTHASE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOPROTEIN P 15095; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MEMBRANE PROSTAGLANDIN E2 SYNTHASE 1; MEMBRANE PROSTAGLANDIN E2 SYNTHASE 2; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTAGLANDIN E RECEPTOR 1; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 3; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E SYNTHASE; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; SERUM AMYLOID A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2 PYRROLIDONE DERIVATIVE; CAY10598; INTERLEUKIN 10; L-161982; TETRAZOLE DERIVATIVE; THIOPHENE DERIVATIVE; TRIAZOLE DERIVATIVE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIET INDUCED OBESITY; EPIDIDYMIS FAT; FAT MASS; GENE EXPRESSION; INFLAMMATION; LIPID DIET; LIPID STORAGE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STROMA CELL; STROMAL VASCULAR CELL; SUBCUTANEOUS FAT; WEIGHT REDUCTION; WHITE ADIPOSE TISSUE; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; IN VITRO STUDY; METABOLISM; PHYSIOLOGY;

ADIPOSE TISSUE; ANIMALS; CHEMOKINE CCL3; CHEMOKINE CXCL10; CHEMOKINES; DINOPROSTONE; IN VITRO TECHNIQUES; INTERLEUKIN-10; INTERLEUKIN-6; INTERLEUKIN-8; MALE; PYRROLIDINONES; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SERUM AMYLOID A PROTEIN; SIGNAL TRANSDUCTION; TETRAZOLES; THIOPHENES; TRIAZOLES;

EID: 84921922997     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M054817     Document Type: Article

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