Novel genotype-phenotype associations demonstrated by high-throughput sequencing in patients with hypertrophic cardiomyopathy

Heart

Volumn 101, Issue 4, 2015, Pages 294-301

  Lopes, Luis R ^a   Syrris, Petros ^a   Guttmann, Oliver P ^a   O'Mahony, Constantinos ^a,b   Tang, Hak Chiaw ^a,c   Dalageorgou, Chrysoula ^a   Jenkins, Sharon ^a   Hubank, Mike ^d   Monserrat, Lorenzo ^e   McKenna, William J ^a   Plagnol, Vincent ^a   Elliott, Perry M ^a,f  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b LONDON CHEST HOSPITAL   (United Kingdom)

^c DEPARTMENT OF CARDIOLOGY   (Singapore)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e HOSPITAL JUAN CANALEJO   (Spain)

^f UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ANK2 GENE; ARTICLE; CARDIOVASCULAR MORTALITY; CHILD; CLINICAL EXAMINATION; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; GENE; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HEART VENTRICLE HYPERTROPHY; HIGH THROUGHPUT SEQUENCING; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; INCIDENCE; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRESCHOOL CHILD; PREVALENCE; PROSPECTIVE STUDY; SCHOOL CHILD; SEX DIFFERENCE; SP GENE; SUDDEN CARDIAC DEATH; VERY ELDERLY; AGE; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; DEATH, SUDDEN, CARDIAC; DNA MUTATIONAL ANALYSIS; ENGLAND; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; MUTATION; PEDIGREE; PHENOTYPE; PREDICTIVE VALUE; PROCEDURES; RETROSPECTIVE STUDY; RISK FACTOR; YOUNG ADULT;

MUSCLE PROTEIN;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; CHILD; DEATH, SUDDEN, CARDIAC; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; KAPLAN-MEIER ESTIMATE; LONDON; MALE; MIDDLE AGED; MUSCLE PROTEINS; MUTATION; PEDIGREE; PHENOTYPE; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 84921912496     PISSN: 13556037     EISSN: 1468201X     Source Type: Journal    
DOI: 10.1136/heartjnl-2014-306387     Document Type: Article

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