Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients

Science Translational Medicine

Volumn 7, Issue 272, 2015, Pages

  Morris, Heather ^a   DeWolf, Susan ^a   Robins, Harlan ^b   Sprangers, Ben ^a   LoCascio, Samuel A ^a   Shonts, Brittany A ^a   Kawai, Tatsuo ^c   Wong, Waichi ^a   Yang, Suxiao ^a   Zuber, Julien ^a   Shen, Yufeng ^a   Sykes, Megan ^a  

^a NewYork Presbyterian Hospital   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASILIXIMAB; CORTICOSTEROID; IMMUNOGLOBULIN; METHYLPREDNISOLONE; MYCOPHENOLIC ACID; RITUXIMAB; T LYMPHOCYTE RECEPTOR BETA CHAIN; TACROLIMUS; THYMOCYTE ANTIBODY; COMPLEMENTARITY DETERMINING REGION; IMMUNOSUPPRESSIVE AGENT; LYMPHOCYTE ANTIGEN RECEPTOR;

ACUTE GRAFT REJECTION; ARTICLE; BONE MARROW TRANSPLANTATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MEDIATED LYMPHOLYSIS; CELL TRACKING; CLINICAL ARTICLE; COMBINED KIDNEY AND BONE MARROW TRANSPLANTATION; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; DONOR REACTIVE T CELL; FEMALE; GRAFT FAILURE; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LIVING DONOR; LYMPHOCYTE CLONE; MIXED LYMPHOCYTE REACTION; PLASMAPHERESIS; T CELL DEPLETION; T LYMPHOCYTE; UNRELATED DONORS; ALLOGRAFT; CYTOLOGY; GRAFT REJECTION; IMMUNOLOGY; KIDNEY FAILURE, CHRONIC; MAJOR HISTOCOMPATIBILITY COMPLEX; METABOLISM; MIXED LYMPHOCYTE CULTURE; TRANSPLANTATION TOLERANCE; TREATMENT OUTCOME;

ALLOGRAFTS; BONE MARROW TRANSPLANTATION; CLONAL DELETION; COMPLEMENTARITY DETERMINING REGIONS; GRAFT REJECTION; HUMANS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; LYMPHOCYTE CULTURE TEST, MIXED; MAJOR HISTOCOMPATIBILITY COMPLEX; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; TRANSPLANTATION TOLERANCE; TREATMENT OUTCOME;

EID: 84921818917     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3010760     Document Type: Article

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