Analysis of changes in phosphorylation of receptor tyrosine kinases: Antibody arrays

Receptor Tyrosine Kinases: Methods and Protocols

Volumn , Issue , 2014, Pages 15-23

  Rani, Sweta ^a,b   O'Driscoll, Lorraine ^b  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Cell lysis; Kinase Activity; Phosphorylation; Protein arrays; Receptor tyrosine kinase

Indexed keywords

EID: 84921774836     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4939-1789-1_2     Document Type: Chapter

References (5)

1. Linger RM, Keating AK, Earp HS et al (2008) TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer. Adv Cancer Res 100:35-83
2. Grassot J, Gouy M, Perriere G et al (2006) Origin and molecular evolution of receptor tyrosine kinases with immunoglobulin-like domains. Mol Biol Evol 23:1232-1241
3. Lemmon MA, Schlessinger J (2010) Cell signaling by receptor tyrosine kinases. Cell 141: 1117-1134
4. Koytiger G, Kaushansky A, Gordus A et al (2013) Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected. Mol Cell Proteomics 12: 1204-1213
5. Konecny GE, Pegram MD, Venkatesan N et al (2006) Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2- overexpressing and trastuzumab-treated breast cancer cells. Cancer Res 66: 1630-1639