Gender differences in patients with first-episode psychosis in the Singapore Early Psychosis Intervention Programme

Early Intervention in Psychiatry

Volumn 10, Issue 6, 2016, Pages 528-534

  Pang, Shirlene ^a   Subramaniam, Mythily ^a   Abdin, Edimansyah ^a   Poon, Lye Yin ^a   Chong, Siow Ann ^a   Verma, Swapna ^a  

^a INSTITUTE OF MENTAL HEALTH   (Singapore)

Author keywords

early intervention; early psychosis; first episode psychosis; gender difference; remission

Indexed keywords

ADOLESCENT; ADULT; AGE; ARTICLE; DISEASE COURSE; EARLY INTERVENTION; EMPLOYMENT; FEMALE; FUNCTIONAL STATUS; GENERAL PRACTITIONER; GLOBAL ASSESSMENT OF FUNCTIONING; HUMAN; MAJOR CLINICAL STUDY; MALE; MARRIED PERSON; OUTPATIENT DEPARTMENT; PATIENT REFERRAL; POSITIVE AND NEGATIVE SYNDROME SCALE; PRIORITY JOURNAL; PSYCHOSIS; REMISSION; SEX DIFFERENCE; SINGAPOREAN; PROGNOSIS; PSYCHOLOGICAL RATING SCALE; PSYCHOTIC DISORDERS; SEXUAL DEVELOPMENT; SINGAPORE; YOUNG ADULT;

ADOLESCENT; ADULT; FEMALE; HUMANS; MALE; PROGNOSIS; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; SEX CHARACTERISTICS; SINGAPORE; YOUNG ADULT;

EID: 84921764631     PISSN: 17517885     EISSN: 17517893     Source Type: Journal    
DOI: 10.1111/eip.12208     Document Type: Article

References (28)

1. Szymanski S, Lieberman JA, Alvir JM et al. Gender differences in onset of illness, treatment response, course, and biological indexes in first-episode schizophrenic patients. Am J Psychiatry 1995; 152: 698–703.
2. Ochoa S, Usall J, Cobo J, Labad X, Kulkarni J. Gender differences in schizophrenia and first-episode psychosis: a comprehensive literature review. Schizophr Res Treatment 2012; 2012: 916198. doi: 10.1155/2012/916198.
3. Thorup A, Petersen L, Jeppesen P, Labad X, Kulkarni J. Gender differences in young adults with first-episode schizophrenia spectrum disorders at baseline in the Danish OPUS Study. J Nerv Ment Dis 2007; 195: 396–405.
4. McGorry PD, Edwards J, Mihalopoulos C, Harrigan S, Jackson HJ. The Early Psychosis Prevention and Intervention Centre (EPPIC): an evolving system of early detection and optimal management. Schizophr Bull 1996; 22: 305–326.
5. Cotton SM, Lambert M, Schimmelmann BG et al. Gender differences in premorbid, entry, treatment, and outcome characteristics in a treated epidemiological sample of 661 patients with first episode psychosis. Schizophr Res 2009; 114: 17–24.
6. Malla AK, Norman RMG, Manchanda R et al. One year outcome in first episode psychosis: influence of DUP and other predictors. Schizophr Res 2002; 54: 231–242.
7. Thomas SP, Nandhra HS. Early intervention in psychosis: a retrospective analysis of clinical and social factors influencing duration of untreated psychosis. Prim Care Companion J Clin Psychiatry 2009; 11: 212–214.
8. Larsen TK, McGlashan TH, Moe LC. First-episode schizophrenia: 1. Early course parameters. Schizophr Bull 1996; 22: 241–256.
9. Køster A, Lajer M, Lindhardt A, Rosenbaum B. Gender differences in first episode psychosis. Soc Psychiatry Psychiatr Epidemiol 2008; 43: 940–946.
10. Leung A, Chue P. Sex differences in schizophrenia: a review of the literature. Acta Psychiatr Scand Suppl 2000; 101: 3–38.
11. Cascio MT, Cella M, Preti A, Meneghelli A, Cocchi A. Gender and duration of untreated psychosis: a systematic review and meta-analysis. Early Interv Psychiatry 2012; 6: 115–127.
12. Verma S, Poon LY, Subramaniam M, Abdin E, Chong SA. The Singapore Early Psychosis Intervention Programme (EPIP): a programme evaluation. Asian J Psychiatr 2012; 5: 63–67.
13. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987; 13: 261–276.
14. Frances A, Pincus HA, First MB. The Global Assessment of Functioning Scale (GAF) in Diagnostic and Statistical Manual of Mental Disorder-IV. Washington, DC: American Psychiatric Association, 1994.
15. Subramaniam M, Pek E, Verma S, Chan YH, Chong SA. Diagnostic stability 2 years after treatment initiation in the Early Psychosis Intervention Programme in Singapore. Aust N Z J Psychiatry 2007; 41: 495–500.
16. Verma S, Poon LY, Subramaniam M, Abdin E. Symptomatic and functional remission in patients with first-episode psychosis. Acta Psychiatr Scand 2012; 126: 282–289.
17. Andreasen NC, Carpenter WT, Kane JM, Lasser RA, Marder SR, Weinberger DR. Remission in schizophrenia: proposed criteria and rationale for consensus. Am J Psychiatry 2005; 162: 441–449.
18. Halbreich U, Kahn LS. Hormonal aspects of schizophrenia: an overview. Psychoneuroendocrinology 2003; 28 (Suppl. 2): 1–16.
19. Thorup A, Albert N, Bertelsena M et al. Gender differences in first-episode psychosis at 5-year follow-up – two different courses of disease? Results from the OPUS study at 5-year follow-up. Eur Psychiatry 2014; 29: 44–51.
20. Wang S, Li W, Zhao J et al. Association of estrogen receptor alpha gene polymorphism with age at onset, general psychopathology symptoms, and therapeutic effect of schizophrenia. Behav Brain Funct 2013; 9: 12.
21. Thomas P, Wood J, Chandra A, Nimgaonkar VL, Deshpande SN. Differences among men and women with schizophrenia: a study of US and Indian samples. Psychiatry Investig 2010; 7: 9–16.
22. Howard L, Leese M, Thornicroft G. Social networks and functional status in patients with psychosis. Acta Psychiatr Scand 2000; 102: 376–385.
23. Lim CS, Subraniam M, Poon LY, Chong SA, Verma S. Cross-ethnic differences in severity of symptomatology of individuals with first-episode schizophrenia spectrum disorder. Early Interv Psychiatry 2011; 5: 242–248.
24. Chang WC, Tang JY, Hui CL et al. Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow up study. Aust N Z J Psychiatry 2011; 45: 199–205.
25. Haro JM, Ciudad A, Alonso J et al. Remission and relapse in the ambulatory treatment of patients with schizophrenia. Outcomes at 3 years. Actas Esp Psiquiatr 2008; 36: 187–196.
26. Zheng S, Poon LY, Verma S. Rates and predictors of service disengagement among patients with first-episode psychosis. Psychiatr Serv 2013; 64: 812–815.
27. Wisdom JP, Manuel JI. Prevalence of substance use in people with first-episode psychosis. J Dual Diagn 2011; 7: 39–49.
28. Verma S, Subramaniam M, Chong SA, Kua EH. Substance abuse in schizophrenia: a Singapore perspective. Soc Psychiatry Psychiatr Epidemiol 2002; 37: 326–328.