ACUTE LYMPHOBLASTIC LEUKEMIA;
CANCER CHEMOTHERAPY;
CANCER PATIENT;
CANCER RESISTANCE;
CELL ADHESION;
CELL VIABILITY;
COMPARATIVE STUDY;
DOSE RESPONSE;
DRUG EFFICACY;
DRUG HALF LIFE;
HUMAN;
IN VITRO STUDY;
IN VIVO STUDY;
LETTER;
LEUKEMIA CELL;
LIGAND BINDING;
MOLECULAR MODEL;
NONHUMAN;
PRE B LYMPHOCYTE;
PRIORITY JOURNAL;
STROMA CELL;
SURVIVAL TIME;
ANALOGS AND DERIVATIVES;
ANIMAL;
CANCER TRANSPLANTATION;
CHEMISTRY;
COCULTURE;
CYTOLOGY;
DRUG EFFECTS;
DRUG RESISTANCE;
INFLAMMATION;
LEUKEMIA;
METABOLISM;
MOUSE;
PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA;
Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy
Hsieh YT, Gang EJ, Geng H, Park E, Huantes S, Chudziak D et al. Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy. Blood 2013; 121: 1814-1818
Potent in vivo suppression of inflammation by selectively targeting the high affinity conformation of integrin alpha4beta1
Vanderslice P, Woodside DG, Caivano AR, Decker ER, Munsch CL, Sherwood SJ et al. Potent in vivo suppression of inflammation by selectively targeting the high affinity conformation of integrin alpha4beta1. Biochem Biophys Res Commun 2010; 400: 619-624
Differential efficacy of a synthetic antagonist of VLA-4 during the course of chronic relapsing experimental autoimmune encephalomyelitis
Cannella B, Gaupp S, Tilton RG, Raine CS. Differential efficacy of a synthetic antagonist of VLA-4 during the course of chronic relapsing experimental autoimmune encephalomyelitis. J Neurosci Res 2003; 71: 407-416
Multiple activation states of VLA-4.Mechanistic differences between adhesion to CS1/fibronectin and to vascular cell adhesion molecule-1
Masumoto A, Hemler ME. Multiple activation states of VLA-4. Mechanistic differences between adhesion to CS1/fibronectin and to vascular cell adhesion molecule-1. J Biol Chem 1993; 268: 228-234
Integrin activation by dithiothreitol or Mn2 induces a ligand-occupied conformation and exposure of a novel NH2-terminal regulatory site on the beta1 integrin chain
Ni H, Li A, Simonsen N, Wilkins JA. Integrin activation by dithiothreitol or Mn2 induces a ligand-occupied conformation and exposure of a novel NH2-terminal regulatory site on the beta1 integrin chain. J Biol Chem 1998; 273: 7981-7987
The role of alpha 4-integrin in T lymphocyte migration into the inflamed and noninflamed central nervous system
Engelhardt B. The role of alpha 4-integrin in T lymphocyte migration into the inflamed and noninflamed central nervous system. Curr Top Microbiol Immunol 1998; 231: 51-64
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia
Park E, Gang EJ, Hsieh YT, Schaefer P, Chae S, Klemm L et al. Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia. Blood 2011; 118: 2191-2199
Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia
Gang EJ, Hsieh YT, Pham J, Zhao Y, Nguyen C, Huantes S et al. Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia. Oncogene 2013; 33: 2169-2178.